Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (396 aa)    
Predicted Functional Partners:
Toce_1047
COGs: COG0280 Phosphotransacetylase; InterPro IPR002505:IPR012147:IPR004614; KEGG: tte:TTE1482 phosphotransacetylase; PFAM: phosphate acetyl/butaryl transferase; PRIAM: Phosphate acetyltransferase; SPTR: Phosphotransacetylase; TIGRFAM: phosphate acetyltransferase; PFAM: Phosphate acetyl/butaryl transferase; TIGRFAM: phosphate acetyltransferase.
 
 
 0.998
Toce_0555
Propanediol utilization protein; Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.
  
 0.994
Toce_1836
Succinate CoA transferase; COGs: COG0427 Acetyl-CoA hydrolase; InterPro IPR017821:IPR003702; KEGG: aoe:Clos_0435 acetyl-CoA hydrolase; PFAM: acetyl-CoA hydrolase/transferase; PRIAM: Acetyl-CoA hydrolase; SPTR: Butyryl-CoA : acetate coenzyem A transferase; TIGRFAM: succinate CoA transferase; PFAM: Acetyl-CoA hydrolase/transferase N-terminal domain; TIGRFAM: succinate CoA transferases.
     
 0.944
Toce_1565
Phosphate butyryltransferase; COGs: COG0280 Phosphotransacetylase; InterPro IPR002505:IPR012147; KEGG: tte:TTE2204 phosphate butyryltransferase; PFAM: phosphate acetyl/butaryl transferase; PRIAM: Phosphate butyryltransferase; SPTR: Phosphotransacetylase; PFAM: Phosphate acetyl/butaryl transferase; TIGRFAM: phosphate butyryltransferase.
 
 0.939
Toce_0830
Phosphate butyryltransferase; COGs: COG0280 Phosphotransacetylase; InterPro IPR012147:IPR002505; KEGG: nth:Nther_1682 phosphate butyryltransferase; PFAM: phosphate acetyl/butaryl transferase; PRIAM: Phosphate butyryltransferase; SPTR: Phosphate butyryltransferase; PFAM: Phosphate acetyl/butaryl transferase; TIGRFAM: phosphate butyryltransferase.
 
 0.937
Toce_0665
COGs: COG1254 Acylphosphatase; InterPro IPR001792:IPR017968; KEGG: tte:TTE1765 acylphosphatase; PFAM: acylphosphatase; SPTR: Acylphosphatase; PFAM: Acylphosphatase.
     
 0.921
Toce_1049
Protein of unknown function DUF177; COGs: COG1399 metal-binding possibly nucleic acid-binding protein; InterPro IPR003772; KEGG: tpd:Teth39_1294 hypothetical protein; PFAM: protein of unknown function DUF177; SPTR: Putative uncharacterized protein; PFAM: Uncharacterized ACR, COG1399.
  
    0.721
rpmF
COGs: COG0333 Ribosomal protein L32; InterPro IPR002677; KEGG: cce:Ccel_2134 ribosomal protein L32; PFAM: ribosomal L32p protein; SPTR: Ribosomal protein L32; TIGRFAM: ribosomal protein L32; PFAM: Ribosomal L32p protein family; TIGRFAM: ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family.
  
  
 0.684
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
  
  
 0.679
Toce_0871
COGs: COG0469 Pyruvate kinase; InterProIPR001697:IPR018209:IPR015793:IPR015794:IPR 008279; KEGG: tte:TTE1815 pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PEP-utilising protein mobile region; SPTR: Pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase, barrel domain; PEP-utilising enzyme, mobile domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family.
  
  
 0.619
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
Server load: low (16%) [HD]