Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Toce_1054degV family protein; COGs: COG1307 conserved hypothetical protein; InterPro IPR003797; KEGG: nth:Nther_1346 DegV family protein; PFAM: DegV family protein; SPTR: DegV family protein; TIGRFAM: degV family protein; PFAM: Uncharacterised protein, DegV family COG1307; TIGRFAM: EDD domain protein, DegV family. (278 aa)    
Predicted Functional Partners:
Toce_1037
DAK2 domain fusion protein YloV; COGs: COG1461 kinase related to dihydroxyacetone kinase; InterPro IPR004007:IPR019986; KEGG: amt:Amet_2771 Dak phosphatase; PFAM: Dak phosphatase; SPTR: Dak phosphatase; TIGRFAM: DAK2 domain fusion protein YloV; PFAM: DAK2 domain; TIGRFAM: DAK2 domain fusion protein YloV.
 
 0.996
Toce_1056
COGs: COG0331 (acyl-carrier-protein) S-malonyltransferase; InterPro IPR014043:IPR004410; KEGG: tte:TTE1473 acyl-carrier-protein S-malonyltransferase; PFAM: Acyl transferase; SPTR: (Acyl-carrier-protein) S-malonyltransferase; TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase domain; TIGRFAM: malonyl CoA-acyl carrier protein transacylase.
  
    0.764
Toce_1057
3-oxoacyl-(acyl-carrier-protein) reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
    0.728
fabH
3-oxoacyl-(acyl-carrier-protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
  
    0.724
Toce_1055
Enoyl-(acyl-carrier-protein) reductase II; COGs: COG2070 Dioxygenase related to 2-nitropropane dioxygenase; InterPro IPR004136:IPR017569; KEGG: tex:Teth514_1725 2-nitropropane dioxygenase, NPD; PFAM: 2-nitropropane dioxygenase NPD; SPTR: 2-nitropropane dioxygenase, NPD; TIGRFAM: enoyl-(acyl-carrier-protein) reductase II; PFAM: 2-nitropropane dioxygenase; TIGRFAM: putative enoyl-(acyl-carrier-protein) reductase II.
       0.723
plsX
Phosphate:acyl-(acyl carrier protein) acyltransferase; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
  
    0.712
Toce_1051
Thioesterase superfamily protein; InterPro IPR001034:IPR006683:IPR017275; KEGG: tit:Thit_1285 protein for fatty acid biosynthesis transcriptional regulation; PFAM: thioesterase superfamily protein; regulatory protein DeoR; SPTR: Protein for fatty acid biosynthesis transcriptional regulation; manually curated; PFAM: Thioesterase superfamily; DeoR-like helix-turn-helix domain.
       0.705
Toce_1036
Protein of unknown function DUF322; COGs: COG1302 conserved hypothetical protein; InterPro IPR005531; KEGG: nth:Nther_1344 protein of unknown function DUF322; PFAM: protein of unknown function DUF322; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF322).
 
    0.635
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
  
    0.561
Toce_1059
3-oxoacyl-(acyl-carrier-protein) synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
  
    0.482
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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