Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cheDCheD; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family. (161 aa)    
Predicted Functional Partners:
Toce_1123
COGs: COG1776 Chemotaxis protein CheC inhibitor of MCP methylation; InterPro IPR007597; KEGG: amt:Amet_2696 CheC, inhibitor of MCP methylation; PFAM: CheC domain protein; SPTR: CheC, inhibitor of MCP methylation; PFAM: CheC-like family.
 0.999
Toce_1110
COGs: COG1776 Chemotaxis protein CheC inhibitor of MCP methylation; InterPro IPR001172:IPR007597:IPR001543:IPR012826; KEGG: tte:TTE1429 flagellar motor switch protein; PFAM: surface presentation of antigens (SPOA) protein; CheC domain protein; SPTR: Chemotaxis protein CheC, inhibitor of MCP methylation; TIGRFAM: flagellar motor switch protein FliN; PFAM: Surface presentation of antigens (SPOA); CheC-like family; TIGRFAM: flagellar motor switch protein FliN.
 
 
 0.998
Toce_1121
CheA signal transduction histidine kinase; COGs: COG0643 Chemotaxis protein histidine kinase and related kinase; InterProIPR008207:IPR003594:IPR002545:IPR004358:IPR 010808:IPR004105:IPR005467; KEGG: tpd:Teth39_1232 CheA signal transduction histidine kinase; PFAM: CheW domain protein; P2 response regulator binding domain protein; Hpt domain protein; Signal transducing histidine kinase homodimeric; ATP-binding region ATPase domain protein; SMART: CheW domain protein; Hpt domain protein; ATP-binding region ATPase domain protein; SPTR: CheA signal transduction histidine kinase; PFAM: CheW- [...]
 
  
 0.992
Toce_0468
Methyl-accepting chemotaxis sensory transducer with Cache sensor; COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR004089:IPR004010; KEGG: mta:Moth_2029 methyl-accepting chemotaxis sensory transducer; PFAM: chemotaxis sensory transducer; Cache domain protein; SMART: chemotaxis sensory transducer; SPTR: Methyl-accepting chemotaxis sensory transducer; PFAM: Cache domain; Methyl-accepting chemotaxis protein (MCP) signaling domain.
 
 0.980
Toce_0469
Methyl-accepting chemotaxis sensory transducer with Cache sensor; COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR004089:IPR003660:IPR004010; KEGG: mta:Moth_1487 methyl-accepting chemotaxis sensory transducer; PFAM: chemotaxis sensory transducer; Cache domain protein; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SPTR: Methyl-accepting chemotaxis sensory transducer; PFAM: Cache domain; HAMP domain; Methyl-accepting chemotaxis protein (MCP) signaling domain.
 
 0.980
Toce_1122
CheW protein; COGs: COG0835 Chemotaxis signal transduction protein; InterPro IPR002545; KEGG: nth:Nther_1419 CheW protein; PFAM: CheW domain protein; SMART: CheW domain protein; SPTR: CheW protein; PFAM: CheW-like domain.
 
  
 0.979
cheB
Response regulator receiver modulated CheB methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
  
 0.966
Toce_1125
RNA polymerase, sigma 28 subunit, FliA/WhiG subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
  
 0.943
flhB
Flagellar biosynthetic protein FlhB; Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the type III secretion exporter family.
  
  
 0.938
Toce_1109
COGs: COG1868 Flagellar motor switch protein; InterPro IPR001689:IPR001543; KEGG: csc:Csac_1269 flagellar motor switch protein FliM; PFAM: flagellar motor switch protein FliM; surface presentation of antigens (SPOA) protein; SPTR: Flagellar motor switch protein FliM; TIGRFAM: flagellar motor switch protein FliM; PFAM: Surface presentation of antigens (SPOA); Flagellar motor switch protein FliM; TIGRFAM: flagellar motor switch protein FliM.
 
  
 0.925
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
Server load: low (22%) [HD]