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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Toce_1127KEGG: hmo:HM1_2253 hypothetical protein; SPTR: Putative uncharacterized protein. (89 aa)    
Predicted Functional Partners:
Toce_1126
Protein of unknown function DUF342; COGs: COG1315 polymerase most protein contain PALM domain HD hydrolase domain and Zn-ribbon domain; InterPro IPR005646; KEGG: cth:Cthe_0498 hypothetical protein; PFAM: protein of unknown function DUF342; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF342).
       0.765
Toce_1125
RNA polymerase, sigma 28 subunit, FliA/WhiG subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
       0.712
Toce_1123
COGs: COG1776 Chemotaxis protein CheC inhibitor of MCP methylation; InterPro IPR007597; KEGG: amt:Amet_2696 CheC, inhibitor of MCP methylation; PFAM: CheC domain protein; SPTR: CheC, inhibitor of MCP methylation; PFAM: CheC-like family.
       0.674
cheD
CheD; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family.
       0.674
Toce_1122
CheW protein; COGs: COG0835 Chemotaxis signal transduction protein; InterPro IPR002545; KEGG: nth:Nther_1419 CheW protein; PFAM: CheW domain protein; SMART: CheW domain protein; SPTR: CheW protein; PFAM: CheW-like domain.
       0.652
Toce_1121
CheA signal transduction histidine kinase; COGs: COG0643 Chemotaxis protein histidine kinase and related kinase; InterProIPR008207:IPR003594:IPR002545:IPR004358:IPR 010808:IPR004105:IPR005467; KEGG: tpd:Teth39_1232 CheA signal transduction histidine kinase; PFAM: CheW domain protein; P2 response regulator binding domain protein; Hpt domain protein; Signal transducing histidine kinase homodimeric; ATP-binding region ATPase domain protein; SMART: CheW domain protein; Hpt domain protein; ATP-binding region ATPase domain protein; SPTR: CheA signal transduction histidine kinase; PFAM: CheW- [...]
       0.622
Toce_1120
Type IV pilus assembly PilZ; COGs: COG5581 glycosyltransferase; InterPro IPR009875; KEGG: nth:Nther_1416 type IV pilus assembly PilZ; PFAM: type IV pilus assembly PilZ; SPTR: Type IV pilus assembly PilZ; PFAM: PilZ domain.
       0.536
Toce_1115
Flagellar biosynthetic protein FliR; Role in flagellar biosynthesis. Belongs to the FliR/MopE/SpaR family.
       0.493
flhB
Flagellar biosynthetic protein FlhB; Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the type III secretion exporter family.
       0.493
flhA
Flagellar biosynthesis protein FlhA; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
       0.493
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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