Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Toce_1128Transposase IS4 family protein; COGs: COG3666 Transposase and inactivated derivatives; InterPro IPR002559; KEGG: tte:TTE2646 transposase; PFAM: transposase IS4 family protein; SPTR: Transposase; PFAM: Transposase DDE domain; Transposase domain (DUF772). (491 aa)    
Predicted Functional Partners:
Toce_1127
KEGG: hmo:HM1_2253 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.492
Toce_1126
Protein of unknown function DUF342; COGs: COG1315 polymerase most protein contain PALM domain HD hydrolase domain and Zn-ribbon domain; InterPro IPR005646; KEGG: cth:Cthe_0498 hypothetical protein; PFAM: protein of unknown function DUF342; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF342).
       0.483
Toce_1129
Transcriptional regulator, BadM/Rrf2 family; COGs: COG1959 transcriptional regulator protein; InterPro IPR000944; KEGG: aoe:Clos_1671 BadM/Rrf2 family transcriptional regulator; PFAM: protein of unknown function UPF0074; SPTR: Transcriptional regulator, BadM/Rrf2 family; TIGRFAM: transcriptional regulator, Rrf2 family; PFAM: Transcriptional regulator; TIGRFAM: rrf2 family protein (putative transcriptional regulator).
       0.473
Toce_1125
RNA polymerase, sigma 28 subunit, FliA/WhiG subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
       0.457
Toce_1123
COGs: COG1776 Chemotaxis protein CheC inhibitor of MCP methylation; InterPro IPR007597; KEGG: amt:Amet_2696 CheC, inhibitor of MCP methylation; PFAM: CheC domain protein; SPTR: CheC, inhibitor of MCP methylation; PFAM: CheC-like family.
       0.436
cheD
CheD; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family.
       0.436
mnmA
tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
       0.428
iscS
Cysteine desulfurase NifS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
       0.426
Toce_1131
FeS cluster assembly scaffold protein NifU; COGs: COG0822 NifU homolog involved in Fe-S cluster formation; InterPro IPR002871:IPR017787; KEGG: chy:CHY_2198 putative FeS assembly protein; PFAM: nitrogen-fixing NifU domain protein; SPTR: Putative FeS assembly protein; TIGRFAM: FeS cluster assembly scaffold protein NifU; PFAM: NifU-like N terminal domain; TIGRFAM: FeS cluster assembly scaffold IscU; FeS cluster assembly scaffold protein NifU, Clostridium type.
       0.426
Toce_1122
CheW protein; COGs: COG0835 Chemotaxis signal transduction protein; InterPro IPR002545; KEGG: nth:Nther_1419 CheW protein; PFAM: CheW domain protein; SMART: CheW domain protein; SPTR: CheW protein; PFAM: CheW-like domain.
       0.424
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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