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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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iscSCysteine desulfurase NifS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. (391 aa)    
Predicted Functional Partners:
Toce_1131
FeS cluster assembly scaffold protein NifU; COGs: COG0822 NifU homolog involved in Fe-S cluster formation; InterPro IPR002871:IPR017787; KEGG: chy:CHY_2198 putative FeS assembly protein; PFAM: nitrogen-fixing NifU domain protein; SPTR: Putative FeS assembly protein; TIGRFAM: FeS cluster assembly scaffold protein NifU; PFAM: NifU-like N terminal domain; TIGRFAM: FeS cluster assembly scaffold IscU; FeS cluster assembly scaffold protein NifU, Clostridium type.
 
 0.996
Toce_0538
FeS cluster assembly scaffold protein NifU; COGs: COG0822 NifU homolog involved in Fe-S cluster formation; InterPro IPR017787:IPR002871; KEGG: mta:Moth_1651 nitrogen-fixing NifU-like; PFAM: nitrogen-fixing NifU domain protein; SPTR: Nitrogen-fixing NifU-like; TIGRFAM: FeS cluster assembly scaffold protein NifU; PFAM: NifU-like N terminal domain; TIGRFAM: FeS cluster assembly scaffold protein NifU, Clostridium type.
 
 0.984
Toce_1129
Transcriptional regulator, BadM/Rrf2 family; COGs: COG1959 transcriptional regulator protein; InterPro IPR000944; KEGG: aoe:Clos_1671 BadM/Rrf2 family transcriptional regulator; PFAM: protein of unknown function UPF0074; SPTR: Transcriptional regulator, BadM/Rrf2 family; TIGRFAM: transcriptional regulator, Rrf2 family; PFAM: Transcriptional regulator; TIGRFAM: rrf2 family protein (putative transcriptional regulator).
 
  
 0.982
Toce_0082
InterPro IPR001455; KEGG: chy:CHY_0625 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: SirA-like protein; Belongs to the sulfur carrier protein TusA family.
   
 0.976
thiI
Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
  
 0.974
Toce_0243
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG3383 Uncharacterized anaerobic dehydrogenase; InterProIPR001041:IPR013027:IPR006963:IPR006656:IPR 000759:IPR017900:IPR006655:IPR017896; KEGG: aoe:Clos_0277 molybdopterin oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; ferredoxin; molybdopterin oxidoreductase Fe4S4 region; molybdopterin oxidoreductase; SPTR: Molybdopterin oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Molybdopterin oxidoreductase; Molybdopterin oxidoreductase Fe4S4 domain; TIGRFAM: glutamate synt [...]
  
 0.946
Toce_0087
Rhodanese domain protein; COGs: COG2897 Rhodanese-related sulfurtransferase; InterPro IPR001763:IPR001307; KEGG: ttr:Tter_1312 rhodanese domain protein; PFAM: Rhodanese domain protein; SMART: Rhodanese domain protein; SPTR: Thiosulfate sulfurtransferase; PFAM: Rhodanese-like domain.
 
 0.934
mnmA
tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
 
  
 0.922
Toce_1465
Aminotransferase class V; COGs: COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase; InterPro IPR000192:IPR016454:IPR020578; KEGG: tte:TTE1663 cysteine sulfinate desulfinase/cysteine desulfurase; PFAM: aminotransferase class V; SPTR: Aminotransferase class V; PFAM: Aminotransferase class-V.
  
  
 
0.906
selD
Selenophosphate synthase; Synthesizes selenophosphate from selenide and ATP.
  
 
 0.905
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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