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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
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speESpermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine. (275 aa)    
Predicted Functional Partners:
speH
Adenosylmethionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
 
 0.999
Toce_1150
Agmatinase; COGs: COG0010 Arginase/agmatinase/formimionoglutamate hydrolase arginase family; InterPro IPR006035:IPR020855:IPR005925; KEGG: tle:Tlet_1302 putative agmatinase; PFAM: Arginase/agmatinase/formiminoglutamase; SPTR: Putative agmatinase; TIGRFAM: agmatinase; PFAM: Arginase family; TIGRFAM: agmatinase; Belongs to the arginase family.
 
 
 0.993
Toce_0364
Methylthioadenosine phosphorylase; Purine nucleoside phosphorylase involved in purine salvage.
  
 
 0.921
Toce_0940
COGs: COG4992 Ornithine/acetylornithine aminotransferase; InterPro IPR005814; KEGG: mta:Moth_1785 aminotransferase; PFAM: aminotransferase class-III; PRIAM: Acetylornithine transaminase; SPTR: Aminotransferase; PFAM: Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
     
 0.910
Toce_0966
Protein of unknown function DUF152; COGs: COG1496 conserved hypothetical protein; InterPro IPR003730; KEGG: tex:Teth514_0117 hypothetical protein; PFAM: protein of unknown function DUF152; SPTR: Putative uncharacterized protein; PFAM: Multi-copper polyphenol oxidoreductase laccase; TIGRFAM: conserved hypothetical protein TIGR00726; Belongs to the multicopper oxidase YfiH/RL5 family.
    
  0.900
Toce_1011
Methylthioadenosine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
    
 0.900
Toce_1656
Purine or other phosphorylase family 1; COGs: COG0775 Nucleoside phosphorylase; InterPro IPR000845; KEGG: dth:DICTH_0360 hypothetical protein; PFAM: purine or other phosphorylase family 1; SPTR: Putative uncharacterized protein; PFAM: Phosphorylase superfamily.
    
 0.900
Toce_2199
COGs: COG1982 Arginine/lysine/ornithine decarboxylase; InterPro IPR000310:IPR008286; KEGG: mta:Moth_2265 arginine decarboxylase; PFAM: Orn/Lys/Arg decarboxylase major region; Orn/Lys/Arg decarboxylase domain protein; SPTR: Arginine decarboxylase; PFAM: Orn/Lys/Arg decarboxylase, C-terminal domain; Orn/Lys/Arg decarboxylase, major domain.
  
 0.900
Toce_1737
COGs: COG0388 amidohydrolase; InterPro IPR003010:IPR001110; KEGG: gym:GYMC10_2272 nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; SPTR: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; PFAM: Carbon-nitrogen hydrolase.
 
  
 0.789
Toce_0010
Orn/Lys/Arg decarboxylase major region; COGs: COG1982 Arginine/lysine/ornithine decarboxylase; InterPro IPR000310:IPR008286; KEGG: cya:CYA_1002 Orn/Lys/Arg decarboxylase; PFAM: Orn/Lys/Arg decarboxylase major region; Orn/Lys/Arg decarboxylase domain protein; SPTR: Orn/Lys/Arg decarboxylase; PFAM: Orn/Lys/Arg decarboxylase, C-terminal domain; Orn/Lys/Arg decarboxylase, major domain.
  
 0.786
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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