| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Toce_1185 | hfq | Toce_1185 | Toce_1186 | Stage V sporulation protein K; COGs: COG0464 ATPase of the AAA+ class; InterPro IPR003593:IPR000641:IPR003959:IPR014232; KEGG: drm:Dred_1880 ATPase central domain-containing protein; PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; SPTR: AAA ATPase, central domain protein; TIGRFAM: stage V sporulation protein K; PFAM: ATPase family associated with various cellular activities (AAA); TIGRFAM: probable Rubsico expression protein CbbX; stage V sporulation protein K. | RNA-binding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.626 |
| Toce_1185 | miaA | Toce_1185 | Toce_1187 | Stage V sporulation protein K; COGs: COG0464 ATPase of the AAA+ class; InterPro IPR003593:IPR000641:IPR003959:IPR014232; KEGG: drm:Dred_1880 ATPase central domain-containing protein; PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; SPTR: AAA ATPase, central domain protein; TIGRFAM: stage V sporulation protein K; PFAM: ATPase family associated with various cellular activities (AAA); TIGRFAM: probable Rubsico expression protein CbbX; stage V sporulation protein K. | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.561 |
| Toce_1185 | miaB | Toce_1185 | Toce_1190 | Stage V sporulation protein K; COGs: COG0464 ATPase of the AAA+ class; InterPro IPR003593:IPR000641:IPR003959:IPR014232; KEGG: drm:Dred_1880 ATPase central domain-containing protein; PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; SPTR: AAA ATPase, central domain protein; TIGRFAM: stage V sporulation protein K; PFAM: ATPase family associated with various cellular activities (AAA); TIGRFAM: probable Rubsico expression protein CbbX; stage V sporulation protein K. | tRNA-i(6)A37 thiotransferase enzyme MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. | 0.464 |
| Toce_1185 | mutL | Toce_1185 | Toce_1188 | Stage V sporulation protein K; COGs: COG0464 ATPase of the AAA+ class; InterPro IPR003593:IPR000641:IPR003959:IPR014232; KEGG: drm:Dred_1880 ATPase central domain-containing protein; PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; SPTR: AAA ATPase, central domain protein; TIGRFAM: stage V sporulation protein K; PFAM: ATPase family associated with various cellular activities (AAA); TIGRFAM: probable Rubsico expression protein CbbX; stage V sporulation protein K. | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.639 |
| Toce_1185 | mutS | Toce_1185 | Toce_1189 | Stage V sporulation protein K; COGs: COG0464 ATPase of the AAA+ class; InterPro IPR003593:IPR000641:IPR003959:IPR014232; KEGG: drm:Dred_1880 ATPase central domain-containing protein; PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; SPTR: AAA ATPase, central domain protein; TIGRFAM: stage V sporulation protein K; PFAM: ATPase family associated with various cellular activities (AAA); TIGRFAM: probable Rubsico expression protein CbbX; stage V sporulation protein K. | DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. | 0.609 |
| Toce_1495 | hfq | Toce_1495 | Toce_1186 | Polynucleotide adenylyltransferase/metal dependent phosphohydrolase; COGs: COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; InterPro IPR002646:IPR006674; KEGG: bhy:BHWA1_01411 polyA polymerase; PFAM: Polynucleotide adenylyltransferase region; metal-dependent phosphohydrolase HD sub domain; SPTR: Uncharacterized domain HDIG-containing protein; PFAM: HD domain; Poly A polymerase head domain. | RNA-binding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.618 |
| Toce_1495 | rnr | Toce_1495 | Toce_1819 | Polynucleotide adenylyltransferase/metal dependent phosphohydrolase; COGs: COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; InterPro IPR002646:IPR006674; KEGG: bhy:BHWA1_01411 polyA polymerase; PFAM: Polynucleotide adenylyltransferase region; metal-dependent phosphohydrolase HD sub domain; SPTR: Uncharacterized domain HDIG-containing protein; PFAM: HD domain; Poly A polymerase head domain. | RNAse R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. | 0.473 |
| Toce_1856 | hfq | Toce_1856 | Toce_1186 | COGs: COG1508 DNA-directed RNA polymerase specialized sigma subunit sigma54 homolog; InterPro IPR000394:IPR007046:IPR007634; KEGG: pth:PTH_2724 DNA-directed RNA polymerase specialized sigma subunit, sigma54-like protein; PFAM: sigma-54 DNA-binding domain protein; sigma-54 factor core-binding region; sigma-54 factor; SPTR: DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog; TIGRFAM: RNA polymerase sigma-54 factor, RpoN; PFAM: Sigma-54 factor, Activator interacting domain (AID); Sigma-54, DNA binding domain; Sigma-54 factor, core binding domain; TIGRFAM: RNA polymeras [...] | RNA-binding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.596 |
| clpX | hfq | Toce_1766 | Toce_1186 | ATP-dependent Clp protease ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | RNA-binding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.782 |
| csrA | hfq | Toce_1593 | Toce_1186 | Carbon storage regulator, CsrA; A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'- UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW. | RNA-binding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.827 |
| hfq | Toce_1185 | Toce_1186 | Toce_1185 | RNA-binding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | Stage V sporulation protein K; COGs: COG0464 ATPase of the AAA+ class; InterPro IPR003593:IPR000641:IPR003959:IPR014232; KEGG: drm:Dred_1880 ATPase central domain-containing protein; PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; SPTR: AAA ATPase, central domain protein; TIGRFAM: stage V sporulation protein K; PFAM: ATPase family associated with various cellular activities (AAA); TIGRFAM: probable Rubsico expression protein CbbX; stage V sporulation protein K. | 0.626 |
| hfq | Toce_1495 | Toce_1186 | Toce_1495 | RNA-binding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | Polynucleotide adenylyltransferase/metal dependent phosphohydrolase; COGs: COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; InterPro IPR002646:IPR006674; KEGG: bhy:BHWA1_01411 polyA polymerase; PFAM: Polynucleotide adenylyltransferase region; metal-dependent phosphohydrolase HD sub domain; SPTR: Uncharacterized domain HDIG-containing protein; PFAM: HD domain; Poly A polymerase head domain. | 0.618 |
| hfq | Toce_1856 | Toce_1186 | Toce_1856 | RNA-binding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | COGs: COG1508 DNA-directed RNA polymerase specialized sigma subunit sigma54 homolog; InterPro IPR000394:IPR007046:IPR007634; KEGG: pth:PTH_2724 DNA-directed RNA polymerase specialized sigma subunit, sigma54-like protein; PFAM: sigma-54 DNA-binding domain protein; sigma-54 factor core-binding region; sigma-54 factor; SPTR: DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog; TIGRFAM: RNA polymerase sigma-54 factor, RpoN; PFAM: Sigma-54 factor, Activator interacting domain (AID); Sigma-54, DNA binding domain; Sigma-54 factor, core binding domain; TIGRFAM: RNA polymeras [...] | 0.596 |
| hfq | clpX | Toce_1186 | Toce_1766 | RNA-binding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | ATP-dependent Clp protease ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | 0.782 |
| hfq | csrA | Toce_1186 | Toce_1593 | RNA-binding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | Carbon storage regulator, CsrA; A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'- UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW. | 0.827 |
| hfq | miaA | Toce_1186 | Toce_1187 | RNA-binding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.907 |
| hfq | miaB | Toce_1186 | Toce_1190 | RNA-binding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | tRNA-i(6)A37 thiotransferase enzyme MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. | 0.764 |
| hfq | mutL | Toce_1186 | Toce_1188 | RNA-binding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.782 |
| hfq | mutS | Toce_1186 | Toce_1189 | RNA-binding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. | 0.700 |
| hfq | rnr | Toce_1186 | Toce_1819 | RNA-binding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | RNAse R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. | 0.610 |
