Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Toce_12162'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. (184 aa)    
Predicted Functional Partners:
cinA
Competence/damage-inducible protein cinA; COGs: COG1058 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; InterPro IPR001453:IPR008136:IPR008135; KEGG: dtu:Dtur_0064 competence/damage-inducible protein CinA; PFAM: CinA domain protein; molybdopterin binding domain; SPTR: CinA-like protein; TIGRFAM: competence/damage-inducible protein CinA; PFAM: Probable molybdopterin binding domain; Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA N-terminal domain; competence/damage-inducible protein CinA C-terminal domain; molybdenum cofactor [...]
     
 0.835
recA
RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
     
 0.699
Toce_1213
SMC domain protein; COGs: COG0419 ATPase involved in DNA repair; InterPro IPR003395; KEGG: cth:Cthe_0944 SMC protein-like protein; PFAM: SMC domain protein; SPTR: SMC domain protein.
  
    0.614
Toce_1211
KEGG: cth:Cthe_1092 hypothetical protein; SPTR: Putative uncharacterized protein.
  
    0.600
Toce_1212
KEGG: cth:Cthe_0943 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.598
Toce_1214
Metallophosphoesterase; COGs: COG0420 DNA repair exonuclease; InterPro IPR004843; KEGG: cth:Cthe_0945 metallophosphoesterase; PFAM: metallophosphoesterase; SPTR: Metallophosphoesterase; PFAM: Calcineurin-like phosphoesterase.
       0.598
Toce_1217
Hypothetical protein.
       0.518
Toce_1219
Vesicle-fusing ATPase; COGs: COG0465 ATP-dependent Zn protease; InterPro IPR003593:IPR003959:IPR000642:IPR003960; KEGG: hor:Hore_11930 microtubule-severing ATPase; PFAM: AAA ATPase central domain protein; peptidase M41; PRIAM: Vesicle-fusing ATPase; SMART: AAA ATPase; SPTR: Microtubule-severing ATPase; PFAM: Peptidase family M41; ATPase family associated with various cellular activities (AAA); TIGRFAM: ATP-dependent metalloprotease FtsH; Belongs to the AAA ATPase family.
  
    0.486
Toce_2077
Radical SAM domain protein; COGs: COG1180 Pyruvate-formate lyase-activating enzyme; InterPro IPR006638:IPR016431:IPR007197; KEGG: tit:Thit_1756 radical SAM domain protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein; PFAM: Radical SAM superfamily.
 
     0.463
Toce_2078
AMMECR1 domain protein; COGs: COG3885 conserved hypothetical protein; InterPro IPR002733:IPR004183; KEGG: tpd:Teth39_0581 hypothetical protein; PFAM: AMMECR1 domain protein; Extradiol ring-cleavage dioxygenase class III protein subunit B; SPTR: AMMECR1 domain protein; PFAM: AMMECR1; Catalytic LigB subunit of aromatic ring-opening dioxygenase; TIGRFAM: conserved hypothetical protein TIGR00296.
 
     0.456
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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