Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
rnjRNA-metabolising metallo-beta-lactamase; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay. (555 aa)    
Predicted Functional Partners:
Toce_1940
Beta-lactamase domain-containing protein; COGs: COG0595 hydrolase of the metallo-beta-lactamase superfamily; KEGG: dau:Daud_0808 beta-lactamase domain-containing protein; SPTR: Beta-lactamase domain protein; PFAM: Metallo-beta-lactamase superfamily; RNA-metabolising metallo-beta-lactamase.
  
  
 
0.911
dapA
Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
 
  
 0.782
Toce_1223
DNA translocase FtsK; COGs: COG1674 DNA segregation ATPase FtsK/SpoIIIE and related protein; InterPro IPR003593:IPR002543:IPR018541; KEGG: pth:PTH_1293 DNA segregation ATPase FtsK/SpoIIIE and related proteins; PFAM: cell divisionFtsK/SpoIIIE; DNA translocase ftsK gamma; SMART: AAA ATPase; SPTR: DNA segregation ATPase FtsK/SpoIIIE and related proteins; PFAM: Ftsk gamma domain; FtsK/SpoIIIE family.
 
    0.751
rny
Metal dependent phosphohydrolase; Endoribonuclease that initiates mRNA decay. Belongs to the RNase Y family.
  
 
 0.673
Toce_1228
Sporulation protein, YlmC/YmxH family; InterPro IPR014238; KEGG: bcq:BCQ_3589 PRC-barrel domain superfamily; SPTR: PRC-barrel domain superfamily; TIGRFAM: sporulation protein, YlmC/YmxH family; PFAM: PRC-barrel domain; TIGRFAM: sporulation protein, YlmC/YmxH family.
       0.650
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
 
    0.560
pnp
Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.
 
  
 0.548
Toce_1308
COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR000092; KEGG: drm:Dred_1076 polyprenyl synthetase; PFAM: Polyprenyl synthetase; SPTR: Farnesyl-diphosphate synthase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
  
    0.531
Toce_1520
Polyprenyl synthetase; COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR000092; KEGG: dsy:DSY2212 hypothetical protein; PFAM: Polyprenyl synthetase; SPTR: Putative uncharacterized protein; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
  
    0.531
Toce_1730
Polyprenyl synthetase; COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR000092; KEGG: hmo:HM1_1960 heptaprenyl diphosphate synthase component II, putative; PFAM: Polyprenyl synthetase; SPTR: Heptaprenyl diphosphate synthase component ii, putative; PFAM: Polyprenyl synthetase; TIGRFAM: heptaprenyl diphosphate synthase component II; Belongs to the FPP/GGPP synthase family.
  
    0.531
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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