Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Toce_1228Sporulation protein, YlmC/YmxH family; InterPro IPR014238; KEGG: bcq:BCQ_3589 PRC-barrel domain superfamily; SPTR: PRC-barrel domain superfamily; TIGRFAM: sporulation protein, YlmC/YmxH family; PFAM: PRC-barrel domain; TIGRFAM: sporulation protein, YlmC/YmxH family. (86 aa)    
Predicted Functional Partners:
Toce_1318
InterPro IPR014194; KEGG: dae:Dtox_2607 stage III sporulation protein AE; PFAM: Sporulation stage III protein AE; SPTR: Stage III sporulation protein AE; TIGRFAM: stage III sporulation protein AE; PFAM: Stage III sporulation protein AE (spore_III_AE); TIGRFAM: stage III sporulation protein AE.
  
     0.711
Toce_0973
KEGG: drm:Dred_1157 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.688
dut
Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.
       0.670
Toce_0964
Sporulation protein, YlmC/YmxH family; COGs: COG1873 conserved hypothetical protein; InterPro IPR007903:IPR014238; KEGG: csc:Csac_1196 PRC-barrel domain-containing protein; PFAM: PRC-barrel domain protein; SPTR: PRC-barrel domain protein; TIGRFAM: sporulation protein, YlmC/YmxH family; PFAM: PRC-barrel domain; TIGRFAM: sporulation protein, YlmC/YmxH family.
  
   
 0.669
Toce_1043
Sporulation integral membrane protein YlbJ; COGs: COG3314 conserved hypothetical protein; InterPro IPR011642:IPR014226; KEGG: hor:Hore_10150 sporulation integral membrane protein YlbJ; PFAM: nucleoside recognition domain protein; SPTR: Sporulation integral membrane protein YlbJ; TIGRFAM: sporulation integral membrane protein YlbJ; PFAM: Nucleoside recognition; TIGRFAM: sporulation integral membrane protein YlbJ.
  
     0.665
Toce_0974
KEGG: amt:Amet_2861 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.660
rnj
RNA-metabolising metallo-beta-lactamase; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
       0.650
Toce_1272
Stage II sporulation protein M; InterPro IPR014196:IPR002798; KEGG: aoe:Clos_1594 sporulation stage II protein M; PFAM: protein of unknown function DUF95 transmembrane; SPTR: Sporulation stage II protein M; TIGRFAM: stage II sporulation protein M; PFAM: Integral membrane protein DUF95; TIGRFAM: stage II sporulation protein M.
 
     0.647
Toce_1319
InterPro IPR014211; KEGG: dae:Dtox_2608 stage III sporulation protein AD; SPTR: Stage III sporulation protein AD; TIGRFAM: stage III sporulation protein AD; PFAM: Stage III sporulation protein AC/AD protein family; TIGRFAM: stage III sporulation protein AD.
  
     0.622
Toce_0960
sigma-E processing peptidase SpoIIGA; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family.
 
     0.604
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
Server load: low (20%) [HD]