STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Toce_1239Protein of unknown function DUF448; COGs: COG2740 nucleic-acid-binding protein implicated in transcription termination; InterPro IPR007393; KEGG: chy:CHY_1768 hypothetical protein; PFAM: protein of unknown function DUF448; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF448). (91 aa)    
Predicted Functional Partners:
Toce_1238
COGs: COG1358 Ribosomal protein HS6-type (S12/L30/L7a); InterPro IPR004038; KEGG: cth:Cthe_0992 50S ribosomal protein L7AE; PFAM: ribosomal protein L7Ae/L30e/S12e/Gadd45; SPTR: LSU ribosomal protein L7AE; PFAM: Ribosomal protein L7Ae/L30e/S12e/Gadd45 family.
  
  
 0.980
nusA
Transcription termination factor NusA; Participates in both transcription termination and antitermination.
 
    0.980
rimP
Protein of unknown function DUF150; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.
  
  
 0.978
infB
Bacterial translation initiation factor 2 (bIF-2); One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
  
  
 0.977
rbfA
Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.
  
    0.895
truB
tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
 
    0.892
Toce_1233
Riboflavin biosynthesis protein RibF; COGs: COG0196 FAD synthase; InterPro IPR015864:IPR015865:IPR002606; KEGG: pth:PTH_1273 FAD synthase; PFAM: FAD synthetase; Riboflavin kinase; SPTR: FAD synthase; TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: Riboflavin kinase; FAD synthetase; TIGRFAM: riboflavin kinase/FMN adenylyltransferase; Belongs to the ribF family.
 
    0.848
Toce_1235
Phosphoesterase RecJ domain protein; COGs: COG0618 Exopolyphosphatase-related protein; InterPro IPR001667:IPR003156; KEGG: cth:Cthe_0989 phosphoesterase, RecJ-like protein; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; SPTR: Phosphoesterase, RecJ-like protein; PFAM: DHH family; DHHA1 domain.
  
    0.848
Toce_0113
LSU ribosomal protein L7AE; InterPro IPR004038:IPR000948; KEGG: sth:STH3081 ribosomal protein L7AE family protein; PFAM: ribosomal protein L7Ae/L30e/S12e/Gadd45; SPTR: Ribosomal protein L7AE family; PFAM: Ribosomal protein L7Ae/L30e/S12e/Gadd45 family.
  
  
 0.741
pnp
Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.
  
    0.728
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
Server load: low (14%) [HD]