Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
nusATranscription termination factor NusA; Participates in both transcription termination and antitermination. (351 aa)    
Predicted Functional Partners:
infB
Bacterial translation initiation factor 2 (bIF-2); One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
  
 0.997
Toce_1239
Protein of unknown function DUF448; COGs: COG2740 nucleic-acid-binding protein implicated in transcription termination; InterPro IPR007393; KEGG: chy:CHY_1768 hypothetical protein; PFAM: protein of unknown function DUF448; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF448).
 
    0.989
rimP
Protein of unknown function DUF150; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.
  
  
 0.988
Toce_1238
COGs: COG1358 Ribosomal protein HS6-type (S12/L30/L7a); InterPro IPR004038; KEGG: cth:Cthe_0992 50S ribosomal protein L7AE; PFAM: ribosomal protein L7Ae/L30e/S12e/Gadd45; SPTR: LSU ribosomal protein L7AE; PFAM: Ribosomal protein L7Ae/L30e/S12e/Gadd45 family.
  
    0.986
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
 
 0.982
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 0.975
nusG
Transcription antitermination protein nusG; Participates in transcription elongation, termination and antitermination.
 
 
 0.973
rplA
LSU ribosomal protein L1P; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
  
 
 0.968
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
   0.964
rpsB
COGs: COG0052 Ribosomal protein S2; InterPro IPR005706:IPR001865:IPR018130; KEGG: gka:GK1249 30S ribosomal protein S2; PFAM: ribosomal protein S2; SPTR: 30S ribosomal protein S2; TIGRFAM: ribosomal protein S2; PFAM: Ribosomal protein S2; TIGRFAM: ribosomal protein S2, bacterial type; Belongs to the universal ribosomal protein uS2 family.
 
 
 0.964
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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