Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Toce_1243MgtC/SapB transporter; COGs: COG1285 membrane protein; InterPro IPR003416:IPR002912; KEGG: swo:Swol_0894 MgtC family protein; PFAM: MgtC/SapB transporter; amino acid-binding ACT domain protein; SPTR: MgtC family protein; PFAM: MgtC family; ACT domain. (220 aa)    
Predicted Functional Partners:
polC
DNA polymerase III catalytic subunit, PolC type; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
       0.790
Toce_1244
COGs: COG1215 Glycosyltransferase probably involved in cell wall biogenesis; InterPro IPR001173; KEGG: hor:Hore_07780 glycosyl transferase family 2; PFAM: glycosyl transferase family 2; SPTR: Glycosyl transferase family 2; PFAM: Glycosyl transferase family 2.
       0.784
proS
prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
       0.649
Toce_1245
YbaK/prolyl-tRNA synthetase associated region; COGs: COG0442 Prolyl-tRNA synthetase; InterPro IPR007214:IPR004154; KEGG: dau:Daud_0618 prolyl-tRNA synthetase; PFAM: YbaK/prolyl-tRNA synthetase associated region; Anticodon-binding domain protein; SPTR: Prolyl-tRNA synthetase; PFAM: YbaK / prolyl-tRNA synthetases associated domain; Anticodon binding domain.
       0.637
infB
Bacterial translation initiation factor 2 (bIF-2); One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
  
    0.566
Toce_0881
ATPase, P-type (transporting), HAD superfamily, subfamily IC; COGs: COG0474 Cation transport ATPase; InterProIPR001757:IPR018303:IPR006069:IPR004014:IPR 008250:IPR005834:IPR006068; KEGG: cpo:COPRO5265_1364 cation-transporting ATPase; PFAM: E1-E2 ATPase-associated domain protein; cation transporting ATPase domain protein; Haloacid dehalogenase domain protein hydrolase; SPTR: Cation-transporting ATPase; TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase; Cation transporting ATPase, C-terminus; Cation transporter/ATPase, N-terminus; haloacid dehaloge [...]
  
 
 0.538
Toce_1342
ATPase, P-type (transporting), HAD superfamily, subfamily IC; COGs: COG0474 Cation transport ATPase; InterProIPR001757:IPR004014:IPR008250:IPR005834:IPR 006068:IPR018303:IPR000695; KEGG: tpd:Teth39_0231 calcium-translocating P-type ATPase, PMCA-type; PFAM: E1-E2 ATPase-associated domain protein; cation transporting ATPase domain protein; Haloacid dehalogenase domain protein hydrolase; SPTR: Calcium-translocating P-type ATPase, PMCA-type; TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase; Cation transporting ATPase, C-terminus; Cation transporter/ [...]
  
 
 0.538
rimP
Protein of unknown function DUF150; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.
       0.537
Toce_1239
Protein of unknown function DUF448; COGs: COG2740 nucleic-acid-binding protein implicated in transcription termination; InterPro IPR007393; KEGG: chy:CHY_1768 hypothetical protein; PFAM: protein of unknown function DUF448; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF448).
       0.536
nusA
Transcription termination factor NusA; Participates in both transcription termination and antitermination.
       0.536
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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