| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Toce_1029 | Toce_1250 | Toce_1029 | Toce_1250 | Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | Membrane-associated zinc metalloprotease; COGs: COG0750 membrane-associated Zn-dependent protease 1; InterPro IPR004387:IPR008915:IPR001478; KEGG: tte:TTE1401 membrane-associated Zn-dependent protease 1; PFAM: peptidase M50; PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein; SPTR: Predicted membrane-associated Zn-dependent protease 1; TIGRFAM: membrane-associated zinc metalloprotease; PFAM: Peptidase family M50; PDZ domain (Also known as DHR or GLGF); TIGRFAM: RIP metalloprotease RseP. | 0.669 |
| Toce_1029 | Toce_1251 | Toce_1029 | Toce_1251 | Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | Sporulation integral membrane protein YtvI; COGs: COG0628 permease; InterPro IPR014227:IPR002549; KEGG: tte:TTE0022 permease; PFAM: protein of unknown function UPF0118; SPTR: Predicted permease; TIGRFAM: sporulation integral membrane protein YtvI; PFAM: Domain of unknown function DUF20; TIGRFAM: sporulation integral membrane protein YtvI. | 0.410 |
| Toce_1250 | Toce_1029 | Toce_1250 | Toce_1029 | Membrane-associated zinc metalloprotease; COGs: COG0750 membrane-associated Zn-dependent protease 1; InterPro IPR004387:IPR008915:IPR001478; KEGG: tte:TTE1401 membrane-associated Zn-dependent protease 1; PFAM: peptidase M50; PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein; SPTR: Predicted membrane-associated Zn-dependent protease 1; TIGRFAM: membrane-associated zinc metalloprotease; PFAM: Peptidase family M50; PDZ domain (Also known as DHR or GLGF); TIGRFAM: RIP metalloprotease RseP. | Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.669 |
| Toce_1250 | Toce_1251 | Toce_1250 | Toce_1251 | Membrane-associated zinc metalloprotease; COGs: COG0750 membrane-associated Zn-dependent protease 1; InterPro IPR004387:IPR008915:IPR001478; KEGG: tte:TTE1401 membrane-associated Zn-dependent protease 1; PFAM: peptidase M50; PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein; SPTR: Predicted membrane-associated Zn-dependent protease 1; TIGRFAM: membrane-associated zinc metalloprotease; PFAM: Peptidase family M50; PDZ domain (Also known as DHR or GLGF); TIGRFAM: RIP metalloprotease RseP. | Sporulation integral membrane protein YtvI; COGs: COG0628 permease; InterPro IPR014227:IPR002549; KEGG: tte:TTE0022 permease; PFAM: protein of unknown function UPF0118; SPTR: Predicted permease; TIGRFAM: sporulation integral membrane protein YtvI; PFAM: Domain of unknown function DUF20; TIGRFAM: sporulation integral membrane protein YtvI. | 0.787 |
| Toce_1250 | Toce_1252 | Toce_1250 | Toce_1252 | Membrane-associated zinc metalloprotease; COGs: COG0750 membrane-associated Zn-dependent protease 1; InterPro IPR004387:IPR008915:IPR001478; KEGG: tte:TTE1401 membrane-associated Zn-dependent protease 1; PFAM: peptidase M50; PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein; SPTR: Predicted membrane-associated Zn-dependent protease 1; TIGRFAM: membrane-associated zinc metalloprotease; PFAM: Peptidase family M50; PDZ domain (Also known as DHR or GLGF); TIGRFAM: RIP metalloprotease RseP. | Phosphatidate cytidylyltransferase; COGs: COG0575 CDP-diglyceride synthetase; InterPro IPR000374; KEGG: amt:Amet_2683 phosphatidate cytidylyltransferase; PFAM: phosphatidate cytidylyltransferase; SPTR: Phosphatidate cytidylyltransferase; PFAM: Cytidylyltransferase family; Belongs to the CDS family. | 0.941 |
| Toce_1250 | Toce_1253 | Toce_1250 | Toce_1253 | Membrane-associated zinc metalloprotease; COGs: COG0750 membrane-associated Zn-dependent protease 1; InterPro IPR004387:IPR008915:IPR001478; KEGG: tte:TTE1401 membrane-associated Zn-dependent protease 1; PFAM: peptidase M50; PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein; SPTR: Predicted membrane-associated Zn-dependent protease 1; TIGRFAM: membrane-associated zinc metalloprotease; PFAM: Peptidase family M50; PDZ domain (Also known as DHR or GLGF); TIGRFAM: RIP metalloprotease RseP. | Undecaprenyl pyrophosphate synthetase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | 0.952 |
| Toce_1250 | frr | Toce_1250 | Toce_1254 | Membrane-associated zinc metalloprotease; COGs: COG0750 membrane-associated Zn-dependent protease 1; InterPro IPR004387:IPR008915:IPR001478; KEGG: tte:TTE1401 membrane-associated Zn-dependent protease 1; PFAM: peptidase M50; PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein; SPTR: Predicted membrane-associated Zn-dependent protease 1; TIGRFAM: membrane-associated zinc metalloprotease; PFAM: Peptidase family M50; PDZ domain (Also known as DHR or GLGF); TIGRFAM: RIP metalloprotease RseP. | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 0.727 |
| Toce_1250 | ispG | Toce_1250 | Toce_1249 | Membrane-associated zinc metalloprotease; COGs: COG0750 membrane-associated Zn-dependent protease 1; InterPro IPR004387:IPR008915:IPR001478; KEGG: tte:TTE1401 membrane-associated Zn-dependent protease 1; PFAM: peptidase M50; PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein; SPTR: Predicted membrane-associated Zn-dependent protease 1; TIGRFAM: membrane-associated zinc metalloprotease; PFAM: Peptidase family M50; PDZ domain (Also known as DHR or GLGF); TIGRFAM: RIP metalloprotease RseP. | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. | 0.783 |
| Toce_1250 | pyrH | Toce_1250 | Toce_1255 | Membrane-associated zinc metalloprotease; COGs: COG0750 membrane-associated Zn-dependent protease 1; InterPro IPR004387:IPR008915:IPR001478; KEGG: tte:TTE1401 membrane-associated Zn-dependent protease 1; PFAM: peptidase M50; PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein; SPTR: Predicted membrane-associated Zn-dependent protease 1; TIGRFAM: membrane-associated zinc metalloprotease; PFAM: Peptidase family M50; PDZ domain (Also known as DHR or GLGF); TIGRFAM: RIP metalloprotease RseP. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.758 |
| Toce_1250 | rpsB | Toce_1250 | Toce_1257 | Membrane-associated zinc metalloprotease; COGs: COG0750 membrane-associated Zn-dependent protease 1; InterPro IPR004387:IPR008915:IPR001478; KEGG: tte:TTE1401 membrane-associated Zn-dependent protease 1; PFAM: peptidase M50; PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein; SPTR: Predicted membrane-associated Zn-dependent protease 1; TIGRFAM: membrane-associated zinc metalloprotease; PFAM: Peptidase family M50; PDZ domain (Also known as DHR or GLGF); TIGRFAM: RIP metalloprotease RseP. | COGs: COG0052 Ribosomal protein S2; InterPro IPR005706:IPR001865:IPR018130; KEGG: gka:GK1249 30S ribosomal protein S2; PFAM: ribosomal protein S2; SPTR: 30S ribosomal protein S2; TIGRFAM: ribosomal protein S2; PFAM: Ribosomal protein S2; TIGRFAM: ribosomal protein S2, bacterial type; Belongs to the universal ribosomal protein uS2 family. | 0.404 |
| Toce_1250 | tsf | Toce_1250 | Toce_1256 | Membrane-associated zinc metalloprotease; COGs: COG0750 membrane-associated Zn-dependent protease 1; InterPro IPR004387:IPR008915:IPR001478; KEGG: tte:TTE1401 membrane-associated Zn-dependent protease 1; PFAM: peptidase M50; PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein; SPTR: Predicted membrane-associated Zn-dependent protease 1; TIGRFAM: membrane-associated zinc metalloprotease; PFAM: Peptidase family M50; PDZ domain (Also known as DHR or GLGF); TIGRFAM: RIP metalloprotease RseP. | Translation elongation factor Ts (EF-Ts); Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. | 0.612 |
| Toce_1251 | Toce_1029 | Toce_1251 | Toce_1029 | Sporulation integral membrane protein YtvI; COGs: COG0628 permease; InterPro IPR014227:IPR002549; KEGG: tte:TTE0022 permease; PFAM: protein of unknown function UPF0118; SPTR: Predicted permease; TIGRFAM: sporulation integral membrane protein YtvI; PFAM: Domain of unknown function DUF20; TIGRFAM: sporulation integral membrane protein YtvI. | Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.410 |
| Toce_1251 | Toce_1250 | Toce_1251 | Toce_1250 | Sporulation integral membrane protein YtvI; COGs: COG0628 permease; InterPro IPR014227:IPR002549; KEGG: tte:TTE0022 permease; PFAM: protein of unknown function UPF0118; SPTR: Predicted permease; TIGRFAM: sporulation integral membrane protein YtvI; PFAM: Domain of unknown function DUF20; TIGRFAM: sporulation integral membrane protein YtvI. | Membrane-associated zinc metalloprotease; COGs: COG0750 membrane-associated Zn-dependent protease 1; InterPro IPR004387:IPR008915:IPR001478; KEGG: tte:TTE1401 membrane-associated Zn-dependent protease 1; PFAM: peptidase M50; PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein; SPTR: Predicted membrane-associated Zn-dependent protease 1; TIGRFAM: membrane-associated zinc metalloprotease; PFAM: Peptidase family M50; PDZ domain (Also known as DHR or GLGF); TIGRFAM: RIP metalloprotease RseP. | 0.787 |
| Toce_1251 | Toce_1252 | Toce_1251 | Toce_1252 | Sporulation integral membrane protein YtvI; COGs: COG0628 permease; InterPro IPR014227:IPR002549; KEGG: tte:TTE0022 permease; PFAM: protein of unknown function UPF0118; SPTR: Predicted permease; TIGRFAM: sporulation integral membrane protein YtvI; PFAM: Domain of unknown function DUF20; TIGRFAM: sporulation integral membrane protein YtvI. | Phosphatidate cytidylyltransferase; COGs: COG0575 CDP-diglyceride synthetase; InterPro IPR000374; KEGG: amt:Amet_2683 phosphatidate cytidylyltransferase; PFAM: phosphatidate cytidylyltransferase; SPTR: Phosphatidate cytidylyltransferase; PFAM: Cytidylyltransferase family; Belongs to the CDS family. | 0.842 |
| Toce_1251 | Toce_1253 | Toce_1251 | Toce_1253 | Sporulation integral membrane protein YtvI; COGs: COG0628 permease; InterPro IPR014227:IPR002549; KEGG: tte:TTE0022 permease; PFAM: protein of unknown function UPF0118; SPTR: Predicted permease; TIGRFAM: sporulation integral membrane protein YtvI; PFAM: Domain of unknown function DUF20; TIGRFAM: sporulation integral membrane protein YtvI. | Undecaprenyl pyrophosphate synthetase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | 0.839 |
| Toce_1251 | frr | Toce_1251 | Toce_1254 | Sporulation integral membrane protein YtvI; COGs: COG0628 permease; InterPro IPR014227:IPR002549; KEGG: tte:TTE0022 permease; PFAM: protein of unknown function UPF0118; SPTR: Predicted permease; TIGRFAM: sporulation integral membrane protein YtvI; PFAM: Domain of unknown function DUF20; TIGRFAM: sporulation integral membrane protein YtvI. | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 0.530 |
| Toce_1251 | ispG | Toce_1251 | Toce_1249 | Sporulation integral membrane protein YtvI; COGs: COG0628 permease; InterPro IPR014227:IPR002549; KEGG: tte:TTE0022 permease; PFAM: protein of unknown function UPF0118; SPTR: Predicted permease; TIGRFAM: sporulation integral membrane protein YtvI; PFAM: Domain of unknown function DUF20; TIGRFAM: sporulation integral membrane protein YtvI. | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. | 0.708 |
| Toce_1251 | pyrH | Toce_1251 | Toce_1255 | Sporulation integral membrane protein YtvI; COGs: COG0628 permease; InterPro IPR014227:IPR002549; KEGG: tte:TTE0022 permease; PFAM: protein of unknown function UPF0118; SPTR: Predicted permease; TIGRFAM: sporulation integral membrane protein YtvI; PFAM: Domain of unknown function DUF20; TIGRFAM: sporulation integral membrane protein YtvI. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.530 |
| Toce_1251 | rpsB | Toce_1251 | Toce_1257 | Sporulation integral membrane protein YtvI; COGs: COG0628 permease; InterPro IPR014227:IPR002549; KEGG: tte:TTE0022 permease; PFAM: protein of unknown function UPF0118; SPTR: Predicted permease; TIGRFAM: sporulation integral membrane protein YtvI; PFAM: Domain of unknown function DUF20; TIGRFAM: sporulation integral membrane protein YtvI. | COGs: COG0052 Ribosomal protein S2; InterPro IPR005706:IPR001865:IPR018130; KEGG: gka:GK1249 30S ribosomal protein S2; PFAM: ribosomal protein S2; SPTR: 30S ribosomal protein S2; TIGRFAM: ribosomal protein S2; PFAM: Ribosomal protein S2; TIGRFAM: ribosomal protein S2, bacterial type; Belongs to the universal ribosomal protein uS2 family. | 0.401 |
| Toce_1251 | tsf | Toce_1251 | Toce_1256 | Sporulation integral membrane protein YtvI; COGs: COG0628 permease; InterPro IPR014227:IPR002549; KEGG: tte:TTE0022 permease; PFAM: protein of unknown function UPF0118; SPTR: Predicted permease; TIGRFAM: sporulation integral membrane protein YtvI; PFAM: Domain of unknown function DUF20; TIGRFAM: sporulation integral membrane protein YtvI. | Translation elongation factor Ts (EF-Ts); Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. | 0.438 |