Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
Toce_1258CoA-substrate-specific enzyme activase; COGs: COG1924 Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain); InterPro IPR008275:IPR002731; KEGG: mta:Moth_1149 CoA enzyme activase; PFAM: ATPase BadF/BadG/BcrA/BcrD type; SPTR: CoA enzyme activase; TIGRFAM: CoA-substrate-specific enzyme activase; PFAM: BadF/BadG/BcrA/BcrD ATPase family; TIGRFAM: CoA-substrate-specific enzyme activase, putative. (323 aa)    
Predicted Functional Partners:
Toce_1259
COGs: COG3581 conserved hypothetical protein; KEGG: hmo:HM1_0328 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: CoA enzyme activase uncharacterised domain (DUF2229).
   
 0.994
Toce_1260
Protein of unknown function DUF2229, CoA enzyme activase; COGs: COG3580 conserved hypothetical protein; InterPro IPR018709; KEGG: amt:Amet_1169 hypothetical protein; PFAM: Protein of unknown function DUF2229, CoA enzyme activase; SPTR: Putative uncharacterized protein; PFAM: CoA enzyme activase uncharacterised domain (DUF2229).
     0.994
Toce_0244
Protein of unknown function DUF2229, CoA enzyme activase; COGs: COG3580 conserved hypothetical protein; InterPro IPR018709; KEGG: nth:Nther_0109 hypothetical protein; PFAM: Protein of unknown function DUF2229, CoA enzyme activase; SPTR: Putative uncharacterized protein; PFAM: CoA enzyme activase uncharacterised domain (DUF2229).
     0.977
Toce_0245
COGs: COG3581 conserved hypothetical protein; KEGG: pth:PTH_1326 hypothetical protein; SPTR: Uncharacterized protein conserved in bacteria.
   
 0.959
Toce_0457
COGs: COG1775 Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit BcrC/BadD/HgdB; InterPro IPR010327; KEGG: tpd:Teth39_0844 2-hydroxyglutaryl-CoA dehydratase, D-component; PFAM: 2-hydroxyglutaryl-CoA dehydratase D-component; SPTR: 2-hydroxyglutaryl-CoA dehydratase D-component; PFAM: 2-hydroxyglutaryl-CoA dehydratase, D-component.
 
 0.869
Toce_1716
COGs: COG1775 Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit BcrC/BadD/HgdB; InterPro IPR010327; KEGG: cbf:CLI_3383 putative R-2-hydroxyglutaryl-CoA dehydratase subunit; PFAM: 2-hydroxyglutaryl-CoA dehydratase D-component; SPTR: Putative uncharacterized protein; PFAM: 2-hydroxyglutaryl-CoA dehydratase, D-component.
 
 0.854
Toce_0456
CoA-substrate-specific enzyme activase; COGs: COG1924 Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain); InterPro IPR008275:IPR010327:IPR002731; KEGG: tte:TTE1113 2-hydroxyglutaryl-CoA dehydratase activator; PFAM: ATPase BadF/BadG/BcrA/BcrD type; 2-hydroxyglutaryl-CoA dehydratase D-component; PRIAM: Benzoyl-CoA reductase; SPTR: CoA-substrate-specific enzyme activase; TIGRFAM: CoA-substrate-specific enzyme activase; PFAM: 2-hydroxyglutaryl-CoA dehydratase, D-component; BadF/BadG/BcrA/BcrD ATPase family; TIGRFAM: CoA-substrate-specific enzyme activase, putative.
 
 
0.778
Toce_1262
Stage V sporulation protein AE; InterPro IPR014204:IPR005562; KEGG: csc:Csac_0090 SpoVA protein; PFAM: SpoVA protein; SPTR: SpoVA protein; TIGRFAM: stage V sporulation protein AE; PFAM: SpoVA protein; TIGRFAM: stage V sporulation protein AE.
       0.608
Toce_1261
KEGG: blo:BL1632 hypothetical protein; SPTR: MFS transporter.
       0.584
Toce_1263
InterPro IPR010894; KEGG: amt:Amet_2220 stage V sporulation protein AD; PFAM: Stage V sporulation AD family protein; SPTR: Stage V sporulation AD family protein; TIGRFAM: stage V sporulation protein AD; PFAM: Stage V sporulation protein AD (SpoVAD); TIGRFAM: stage V sporulation protein AD.
  
    0.583
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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