Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Toce_1273PHP domain protein; COGs: COG1379 conserved hypothetical protein; InterPro IPR004013; KEGG: tte:TTE1311 hypothetical protein; PFAM: PHP domain protein; SPTR: Putative uncharacterized protein; TIGRFAM: conserved hypothetical protein TIGR00375. (390 aa)    
Predicted Functional Partners:
Toce_1758
COGs: COG0210 Superfamily I DNA and RNA helicase; InterProIPR005751:IPR000212:IPR014016:IPR014017:IPR 005829; KEGG: cth:Cthe_2876 ATP-dependent DNA helicase PcrA; PFAM: UvrD/REP helicase; SPTR: ATP-dependent DNA helicase PcrA; TIGRFAM: ATP-dependent DNA helicase PcrA; PFAM: UvrD/REP helicase; TIGRFAM: glutamate--cysteine ligase/gamma-glutamylcysteine synthetase, Streptococcus agalactiae type; ATP-dependent DNA helicase PcrA.
      0.904
Toce_1274
NUDIX hydrolase; InterPro IPR000086:IPR020084; KEGG: tte:TTE1310 NTP pyrophosphohydrolase including oxidative damage repair enzyme; PFAM: NUDIX hydrolase; SPTR: NTP pyrophosphohydrolases including oxidative damage repair enzymes; PFAM: NUDIX domain; TIGRFAM: nudix hydrolase, YffH family.
  
    0.828
Toce_1275
KEGG: drm:Dred_1093 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.812
Toce_1277
KEGG: tte:TTE1306 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF3186).
       0.728
Toce_1278
Thiamin pyrophosphokinase catalytic region; COGs: COG4825 Uncharacterized membrane-anchored protein; InterPro IPR007371:IPR000209; KEGG: tit:Thit_1099 thiamin pyrophosphokinase catalytic region; PFAM: Thiamin pyrophosphokinase catalytic region; SPTR: Thiamin pyrophosphokinase catalytic region; PFAM: Thiamine pyrophosphokinase C terminal; Thiamin pyrophosphokinase, catalytic domain.
       0.719
Toce_1276
KEGG: dau:Daud_1611 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Glycosyl transferase family 4.
       0.715
Toce_1272
Stage II sporulation protein M; InterPro IPR014196:IPR002798; KEGG: aoe:Clos_1594 sporulation stage II protein M; PFAM: protein of unknown function DUF95 transmembrane; SPTR: Sporulation stage II protein M; TIGRFAM: stage II sporulation protein M; PFAM: Integral membrane protein DUF95; TIGRFAM: stage II sporulation protein M.
 
     0.710
Toce_1595
KEGG: amt:Amet_0729 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.516
Toce_0860
KEGG: sth:STH1710 hypothetical protein; SPTR: UPF0342 protein STH1710; PFAM: Protein of unknown function (DUF964); Belongs to the UPF0342 family.
  
     0.495
Toce_1100
MgtE intracellular region; InterPro IPR006668; KEGG: tte:TTE1437 hypothetical protein; PFAM: MgtE intracellular region; SPTR: Putative uncharacterized protein; PFAM: MgtE intracellular N domain.
  
     0.492
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
Server load: low (8%) [HD]