Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
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Toce_1301Stage IV sporulation protein B; InterPro IPR014219:IPR008763; KEGG: tpd:Teth39_1108 peptidase S55, SpoIVB; PFAM: peptidase S55 SpoIVB; PRIAM: SpoIVB peptidase; SPTR: Peptidase S55, SpoIVB; TIGRFAM: stage IV sporulation protein B; PFAM: SpoIVB peptidase S55; TIGRFAM: stage IV sporulation protein B. (437 aa)    
Predicted Functional Partners:
Toce_1300
Sporulation transcriptional activator Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
   
 0.984
spoIIAB
Putative anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
   
 0.829
gpr
Spore protease; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family.
  
    0.825
Toce_1263
InterPro IPR010894; KEGG: amt:Amet_2220 stage V sporulation protein AD; PFAM: Stage V sporulation AD family protein; SPTR: Stage V sporulation AD family protein; TIGRFAM: stage V sporulation protein AD; PFAM: Stage V sporulation protein AD (SpoVAD); TIGRFAM: stage V sporulation protein AD.
  
  
 0.812
Toce_1318
InterPro IPR014194; KEGG: dae:Dtox_2607 stage III sporulation protein AE; PFAM: Sporulation stage III protein AE; SPTR: Stage III sporulation protein AE; TIGRFAM: stage III sporulation protein AE; PFAM: Stage III sporulation protein AE (spore_III_AE); TIGRFAM: stage III sporulation protein AE.
 
   
 0.810
Toce_1319
InterPro IPR014211; KEGG: dae:Dtox_2608 stage III sporulation protein AD; SPTR: Stage III sporulation protein AD; TIGRFAM: stage III sporulation protein AD; PFAM: Stage III sporulation protein AC/AD protein family; TIGRFAM: stage III sporulation protein AD.
 
   
 0.807
Toce_1264
Stage V sporulation protein AC; InterPro IPR014203:IPR005562; KEGG: cdl:CDR20291_0702 stage V sporulation protein AC; PFAM: SpoVA protein; SPTR: Putative uncharacterized protein; TIGRFAM: stage V sporulation protein AC; PFAM: SpoVA protein; TIGRFAM: stage V sporulation protein AC.
 
   
 0.803
Toce_1322
Stage III sporulation protein AA; COGs: COG3854 conserved hypothetical protein; InterPro IPR014217:IPR003593; KEGG: tpd:Teth39_1088 AAA ATPase; SMART: AAA ATPase; SPTR: AAA ATPase; TIGRFAM: stage III sporulation protein AA; TIGRFAM: stage III sporulation protein AA.
 
   
 0.803
Toce_1262
Stage V sporulation protein AE; InterPro IPR014204:IPR005562; KEGG: csc:Csac_0090 SpoVA protein; PFAM: SpoVA protein; SPTR: SpoVA protein; TIGRFAM: stage V sporulation protein AE; PFAM: SpoVA protein; TIGRFAM: stage V sporulation protein AE.
  
   
 0.802
Toce_0960
sigma-E processing peptidase SpoIIGA; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family.
  
   
 0.800
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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