| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Toce_0940 | argG | Toce_0940 | Toce_0156 | COGs: COG4992 Ornithine/acetylornithine aminotransferase; InterPro IPR005814; KEGG: mta:Moth_1785 aminotransferase; PFAM: aminotransferase class-III; PRIAM: Acetylornithine transaminase; SPTR: Aminotransferase; PFAM: Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | COGs: COG0137 Argininosuccinate synthase; InterPro IPR001518:IPR018223; KEGG: gyc:GYMC61_0760 argininosuccinate synthase; PFAM: argininosuccinate synthase; PRIAM: Argininosuccinate synthase; SPTR: Argininosuccinate synthase; TIGRFAM: argininosuccinate synthase; PFAM: Arginosuccinate synthase; TIGRFAM: argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.924 |
| Toce_0940 | argH | Toce_0940 | Toce_0157 | COGs: COG4992 Ornithine/acetylornithine aminotransferase; InterPro IPR005814; KEGG: mta:Moth_1785 aminotransferase; PFAM: aminotransferase class-III; PRIAM: Acetylornithine transaminase; SPTR: Aminotransferase; PFAM: Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | COGs: COG0165 Argininosuccinate lyase; InterPro IPR009049:IPR000362:IPR003031:IPR020557; KEGG: sth:STH486 argininosuccinate lyase; PFAM: fumarate lyase; SPTR: Argininosuccinate lyase; TIGRFAM: argininosuccinate lyase; PFAM: Lyase; TIGRFAM: argininosuccinate lyase. | 0.915 |
| Toce_0940 | argR | Toce_0940 | Toce_1303 | COGs: COG4992 Ornithine/acetylornithine aminotransferase; InterPro IPR005814; KEGG: mta:Moth_1785 aminotransferase; PFAM: aminotransferase class-III; PRIAM: Acetylornithine transaminase; SPTR: Aminotransferase; PFAM: Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Transcriptional regulator, ArgR family; Regulates arginine biosynthesis genes. | 0.775 |
| Toce_1300 | Toce_1302 | Toce_1300 | Toce_1302 | Sporulation transcriptional activator Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | 0.584 |
| Toce_1300 | Toce_1306 | Toce_1300 | Toce_1306 | Sporulation transcriptional activator Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | COGs: COG1189 rRNA methylase; InterPro IPR004538:IPR002942:IPR002877; KEGG: cth:Cthe_0827 hemolysin A; PFAM: RNA-binding S4 domain protein; ribosomal RNA methyltransferase RrmJ/FtsJ; SMART: RNA-binding S4 domain protein; SPTR: Hemolysin A; TIGRFAM: hemolysin A; manually curated; PFAM: S4 domain; FtsJ-like methyltransferase; TIGRFAM: hemolysin TlyA family protein. | 0.458 |
| Toce_1300 | Toce_1307 | Toce_1300 | Toce_1307 | Sporulation transcriptional activator Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | KEGG: ctc:CTC01576 membrane spanning protein; SPTR: Membrane spanning protein. | 0.447 |
| Toce_1300 | argR | Toce_1300 | Toce_1303 | Sporulation transcriptional activator Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | Transcriptional regulator, ArgR family; Regulates arginine biosynthesis genes. | 0.599 |
| Toce_1300 | nadK | Toce_1300 | Toce_1304 | Sporulation transcriptional activator Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.484 |
| Toce_1302 | Toce_1300 | Toce_1302 | Toce_1300 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | Sporulation transcriptional activator Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | 0.584 |
| Toce_1302 | Toce_1305 | Toce_1302 | Toce_1305 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | KEGG: drm:Dred_1080 hypothetical protein; SPTR: Putative uncharacterized protein. | 0.733 |
| Toce_1302 | Toce_1306 | Toce_1302 | Toce_1306 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | COGs: COG1189 rRNA methylase; InterPro IPR004538:IPR002942:IPR002877; KEGG: cth:Cthe_0827 hemolysin A; PFAM: RNA-binding S4 domain protein; ribosomal RNA methyltransferase RrmJ/FtsJ; SMART: RNA-binding S4 domain protein; SPTR: Hemolysin A; TIGRFAM: hemolysin A; manually curated; PFAM: S4 domain; FtsJ-like methyltransferase; TIGRFAM: hemolysin TlyA family protein. | 0.802 |
| Toce_1302 | Toce_1307 | Toce_1302 | Toce_1307 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | KEGG: ctc:CTC01576 membrane spanning protein; SPTR: Membrane spanning protein. | 0.719 |
| Toce_1302 | argR | Toce_1302 | Toce_1303 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | Transcriptional regulator, ArgR family; Regulates arginine biosynthesis genes. | 0.868 |
| Toce_1302 | nadK | Toce_1302 | Toce_1304 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.960 |
| Toce_1305 | Toce_1302 | Toce_1305 | Toce_1302 | KEGG: drm:Dred_1080 hypothetical protein; SPTR: Putative uncharacterized protein. | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | 0.733 |
| Toce_1305 | Toce_1306 | Toce_1305 | Toce_1306 | KEGG: drm:Dred_1080 hypothetical protein; SPTR: Putative uncharacterized protein. | COGs: COG1189 rRNA methylase; InterPro IPR004538:IPR002942:IPR002877; KEGG: cth:Cthe_0827 hemolysin A; PFAM: RNA-binding S4 domain protein; ribosomal RNA methyltransferase RrmJ/FtsJ; SMART: RNA-binding S4 domain protein; SPTR: Hemolysin A; TIGRFAM: hemolysin A; manually curated; PFAM: S4 domain; FtsJ-like methyltransferase; TIGRFAM: hemolysin TlyA family protein. | 0.759 |
| Toce_1305 | Toce_1307 | Toce_1305 | Toce_1307 | KEGG: drm:Dred_1080 hypothetical protein; SPTR: Putative uncharacterized protein. | KEGG: ctc:CTC01576 membrane spanning protein; SPTR: Membrane spanning protein. | 0.720 |
| Toce_1305 | argR | Toce_1305 | Toce_1303 | KEGG: drm:Dred_1080 hypothetical protein; SPTR: Putative uncharacterized protein. | Transcriptional regulator, ArgR family; Regulates arginine biosynthesis genes. | 0.754 |
| Toce_1305 | nadK | Toce_1305 | Toce_1304 | KEGG: drm:Dred_1080 hypothetical protein; SPTR: Putative uncharacterized protein. | ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.812 |
| Toce_1306 | Toce_1300 | Toce_1306 | Toce_1300 | COGs: COG1189 rRNA methylase; InterPro IPR004538:IPR002942:IPR002877; KEGG: cth:Cthe_0827 hemolysin A; PFAM: RNA-binding S4 domain protein; ribosomal RNA methyltransferase RrmJ/FtsJ; SMART: RNA-binding S4 domain protein; SPTR: Hemolysin A; TIGRFAM: hemolysin A; manually curated; PFAM: S4 domain; FtsJ-like methyltransferase; TIGRFAM: hemolysin TlyA family protein. | Sporulation transcriptional activator Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | 0.458 |