Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Toce_1307KEGG: ctc:CTC01576 membrane spanning protein; SPTR: Membrane spanning protein. (202 aa)    
Predicted Functional Partners:
Toce_1306
COGs: COG1189 rRNA methylase; InterPro IPR004538:IPR002942:IPR002877; KEGG: cth:Cthe_0827 hemolysin A; PFAM: RNA-binding S4 domain protein; ribosomal RNA methyltransferase RrmJ/FtsJ; SMART: RNA-binding S4 domain protein; SPTR: Hemolysin A; TIGRFAM: hemolysin A; manually curated; PFAM: S4 domain; FtsJ-like methyltransferase; TIGRFAM: hemolysin TlyA family protein.
     
 0.837
nadK
ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
       0.780
argR
Transcriptional regulator, ArgR family; Regulates arginine biosynthesis genes.
  
  
 0.769
Toce_1305
KEGG: drm:Dred_1080 hypothetical protein; SPTR: Putative uncharacterized protein.
     
 0.720
Toce_1302
DNA repair protein RecN; May be involved in recombinational repair of damaged DNA.
       0.719
Toce_0113
LSU ribosomal protein L7AE; InterPro IPR004038:IPR000948; KEGG: sth:STH3081 ribosomal protein L7AE family protein; PFAM: ribosomal protein L7Ae/L30e/S12e/Gadd45; SPTR: Ribosomal protein L7AE family; PFAM: Ribosomal protein L7Ae/L30e/S12e/Gadd45 family.
  
     0.676
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
     
 0.661
Toce_0141
LSU ribosomal protein L14E; KEGG: cth:Cthe_2926 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.656
Toce_1301
Stage IV sporulation protein B; InterPro IPR014219:IPR008763; KEGG: tpd:Teth39_1108 peptidase S55, SpoIVB; PFAM: peptidase S55 SpoIVB; PRIAM: SpoIVB peptidase; SPTR: Peptidase S55, SpoIVB; TIGRFAM: stage IV sporulation protein B; PFAM: SpoIVB peptidase S55; TIGRFAM: stage IV sporulation protein B.
       0.522
Toce_1300
Sporulation transcriptional activator Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
       0.447
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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