Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
xseAExodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. (410 aa)    
Predicted Functional Partners:
xseB
Exodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family.
 
 0.999
Toce_1308
COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR000092; KEGG: drm:Dred_1076 polyprenyl synthetase; PFAM: Polyprenyl synthetase; SPTR: Farnesyl-diphosphate synthase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
 
  
 0.965
folD
5,10-methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
 
    0.961
nusB
NusB antitermination factor; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
  
    0.844
Toce_1312
Protein of unknown function DUF2273; InterPro IPR018730; KEGG: cce:Ccel_1906 hypothetical protein; PFAM: Protein of unknown function DUF2273; SPTR: Putative uncharacterized protein; PFAM: Small integral membrane protein (DUF2273).
       0.779
Toce_1313
Protein of unknown function DUF322; InterPro IPR005531; KEGG: mta:Moth_1522 hypothetical protein; PFAM: protein of unknown function DUF322; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF322).
       0.771
Toce_1302
DNA repair protein RecN; May be involved in recombinational repair of damaged DNA.
 
   
 0.720
Toce_1314
Protein of unknown function DUF322; COGs: COG1302 conserved hypothetical protein; InterPro IPR005531:IPR005829; KEGG: tit:Thit_1085 protein of unknown function DUF322; PFAM: protein of unknown function DUF322; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF322).
       0.654
Toce_1096
COGs: COG1536 Flagellar motor switch protein; InterPro IPR000090; KEGG: cth:Cthe_0466 flagellar motor switch protein G; PFAM: flagellar motor switch protein FliG; SPTR: Flagellar motor switch protein FliG; TIGRFAM: flagellar motor switch protein FliG; PFAM: FliG C-terminal domain; TIGRFAM: flagellar motor switch protein FliG.
   
   0.551
ruvB
Holliday junction DNA helicase subunit RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.
 
   
 0.549
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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