STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Toce_1337HAD superfamily (subfamily IIIA) phosphatase, TIGR01668; COGs: COG2179 hydrolase of the HAD superfamily; InterPro IPR010021:IPR006549:IPR005834; KEGG: tte:TTE1260 HAD superfamily hydrolase; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: HAD superfamily (Subfamily IIIA) phosphatase, TIGR01668; TIGRFAM: HAD superfamily (subfamily IIIA) phosphatase, TIGR01668; hydrolase, HAD-superfamily, subfamily IIIA; PFAM: Protein of unknown function; TIGRFAM: HAD-superfamily hydrolase, subfamily IIIA; HAD superfamily (subfamily IIIA) phosphatase, TIGR01668. (168 aa)    
Predicted Functional Partners:
aroE
Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
 
    0.926
Toce_1338
RNA polymerase, sigma 27/28 subunit, RpsK/SigK; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
       0.726
aroK
3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the shikimate kinase family.
      0.724
Toce_1336
COGs: COG2804 Type II secretory pathway ATPase PulE/Tfp pilus assembly pathway ATPase PilB; InterPro IPR007831:IPR001482; KEGG: amt:Amet_3482 type II secretion system protein E; PFAM: type II secretion system protein E; General secretory system II protein E domain protein; SPTR: Type II secretion system protein E; PFAM: Type II/IV secretion system protein; GSPII_E N-terminal domain; TIGRFAM: general secretory pathway protein E.
       0.657
Toce_1330
Late competence development protein ComFB; InterPro IPR019657; KEGG: cth:Cthe_0851 hypothetical protein; PFAM: Late competence development protein ComFB; SPTR: Putative uncharacterized protein; PFAM: Late competence development protein ComFB.
 
     0.576
Toce_1325
Peptidase M24; COGs: COG0006 Xaa-Pro aminopeptidase; InterPro IPR000587:IPR000994; KEGG: drm:Dred_1051 peptidase M24; PFAM: peptidase M24; creatinase; SPTR: Peptidase M24; PFAM: Metallopeptidase family M24; Creatinase/Prolidase N-terminal domain.
       0.553
efp
Translation elongation factor P (EF-P); Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
       0.525
Toce_0895
DNA internalization-related competence protein ComEC/Rec2; COGs: COG2333 hydrolase (metallo-beta-lactamase superfamily); InterPro IPR004797:IPR004477; KEGG: tit:Thit_0878 DNA internalization-related competence protein ComEC/Rec2; PFAM: ComEC/Rec2-related protein; SPTR: DNA internalization-related competence protein ComEC/Rec2; TIGRFAM: DNA internalization-related competence protein ComEC/Rec2; ComEC/Rec2-related protein; PFAM: Competence protein; Metallo-beta-lactamase superfamily; TIGRFAM: ComEC/Rec2-related protein; DNA internalization-related competence protein ComEC/Rec2.
 
     0.517
Toce_1323
KEGG: mta:Moth_1537 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.511
Toce_1329
COGs: COG4972 Tfp pilus assembly protein ATPase PilM; InterPro IPR005883:IPR003494; KEGG: mxa:MXAN_5776 type IV pilus biogenesis protein PilM; PFAM: cell division protein FtsA; SPTR: Type IV pilus biogenesis protein PilM; TIGRFAM: type IV pilus assembly protein PilM; PFAM: Competence protein A; Cell division protein FtsA; TIGRFAM: type IV pilus assembly protein PilM.
 
     0.505
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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