Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
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Toce_1342ATPase, P-type (transporting), HAD superfamily, subfamily IC; COGs: COG0474 Cation transport ATPase; InterProIPR001757:IPR004014:IPR008250:IPR005834:IPR 006068:IPR018303:IPR000695; KEGG: tpd:Teth39_0231 calcium-translocating P-type ATPase, PMCA-type; PFAM: E1-E2 ATPase-associated domain protein; cation transporting ATPase domain protein; Haloacid dehalogenase domain protein hydrolase; SPTR: Calcium-translocating P-type ATPase, PMCA-type; TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase; Cation transporting ATPase, C-terminus; Cation transporter/ [...] (901 aa)    
Predicted Functional Partners:
Toce_1243
MgtC/SapB transporter; COGs: COG1285 membrane protein; InterPro IPR003416:IPR002912; KEGG: swo:Swol_0894 MgtC family protein; PFAM: MgtC/SapB transporter; amino acid-binding ACT domain protein; SPTR: MgtC family protein; PFAM: MgtC family; ACT domain.
  
 
 0.538
rpsH
SSU ribosomal protein S8P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.
    
   0.525
Toce_1731
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG1252 NADH dehydrogenase FAD-containing subunit; InterPro IPR013027:IPR011637; KEGG: hor:Hore_14860 NADH dehydrogenase, FAD-containing subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; DoxX family protein; SPTR: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; DoxX.
   
 0.512
rpsM
SSU ribosomal protein S13P; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family.
   
   0.511
rpsE
SSU ribosomal protein S5P; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.
    
 
 0.500
Toce_1588
COGs: COG0438 Glycosyltransferase; InterProIPR001296:IPR013216:IPR001173:IPR019734:IPR 013026:IPR000276; KEGG: tnp:Tnap_0554 glycosyl transferase family 2; PFAM: glycosyl transferase family 2; Methyltransferase type 11; glycosyl transferase group 1; SMART: Tetratricopeptide repeat; SPTR: Glycosyl transferase family 2; PFAM: Methyltransferase domain; Glycosyl transferases group 1; Glycosyl transferase family 2.
  
 
 0.490
rplD
LSU ribosomal protein L4P; Forms part of the polypeptide exit tunnel.
    
   0.478
Toce_1824
SPFH domain, Band 7 family protein; COGs: COG0330 Membrane protease subunits stomatin/prohibitin homologs; InterPro IPR001107:IPR001972; KEGG: cpo:COPRO5265_0367 erythrocyte band 7 integral membrane protein; PFAM: band 7 protein; SMART: band 7 protein; SPTR: Erythrocyte band 7 integral membrane protein; PFAM: SPFH domain / Band 7 family.
   
 0.470
Toce_0485
Peptidase S8 and S53 subtilisin kexin sedolisin; COGs: COG1404 Subtilisin-like serine protease; InterPro IPR000209; KEGG: mta:Moth_2027 aerolysin; PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; SPTR: Aerolysin. Serine peptidase. MEROPS family S08A; PFAM: Subtilase family; Belongs to the peptidase S8 family.
   
 
 0.439
Toce_1777
Peptidase S8 and S53 subtilisin kexin sedolisin; COGs: COG1404 Subtilisin-like serine protease; InterPro IPR010259:IPR000209:IPR007280:IPR018247; KEGG: tex:Teth514_2192 peptidase S8 and S53, subtilisin, kexin, sedolisin; PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; proteinase inhibitor I9 subtilisin propeptide; peptidase domain protein; SPTR: Peptidase S8 and S53, subtilisin, kexin, sedolisin; PFAM: Bacterial pre-peptidase C-terminal domain; Peptidase inhibitor I9; Subtilase family.
   
 
 0.439
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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