| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Toce_0086 | Toce_1146 | Toce_0086 | Toce_1146 | FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterPro IPR013027:IPR004017:IPR000759:IPR017900; KEGG: vpa:VP1199 putative glutamate synthase, small chain; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; protein of unknown function DUF224 cysteine-rich region domain protein; SPTR: Pyridine nucleotide-disulphide oxidoreductase family protein; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Cysteine-rich domain. | Conserved hypothetical protein; COGs: COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductase; InterPro IPR006058; KEGG: tex:Teth514_1576 hypothetical protein; SPTR: Oxidoreductase FAD-binding domain protein. | 0.922 |
| Toce_0086 | Toce_1353 | Toce_0086 | Toce_1353 | FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterPro IPR013027:IPR004017:IPR000759:IPR017900; KEGG: vpa:VP1199 putative glutamate synthase, small chain; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; protein of unknown function DUF224 cysteine-rich region domain protein; SPTR: Pyridine nucleotide-disulphide oxidoreductase family protein; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Cysteine-rich domain. | COGs: COG0667 oxidoreductase (related to aryl-alcohol dehydrogenase); InterPro IPR001395:IPR017896:IPR017900:IPR020471; KEGG: cth:Cthe_0152 aldo/keto reductase; PFAM: aldo/keto reductase; SPTR: Aldo/keto reductase; PFAM: Aldo/keto reductase family. | 0.677 |
| Toce_0086 | Toce_2213 | Toce_0086 | Toce_2213 | FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterPro IPR013027:IPR004017:IPR000759:IPR017900; KEGG: vpa:VP1199 putative glutamate synthase, small chain; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; protein of unknown function DUF224 cysteine-rich region domain protein; SPTR: Pyridine nucleotide-disulphide oxidoreductase family protein; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Cysteine-rich domain. | Nitrate reductase; COGs: COG0243 Anaerobic dehydrogenase typically selenocysteine-containing; InterPro IPR006655:IPR006963:IPR006656:IPR006657; KEGG: drm:Dred_1345 molybdopterin oxidoreductase; PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide-binding region; PRIAM: Nitrate reductase; SPTR: Molybdopterin oxidoreductase; PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain; Molybdopterin oxidoreductase Fe4S4 domain; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | 0.552 |
| Toce_0228 | Toce_1353 | Toce_0228 | Toce_1353 | COGs: COG1035 Coenzyme F420-reducing hydrogenase beta subunit; InterPro IPR007525:IPR017900:IPR017896; KEGG: dps:DPPB80 related to F420H2-dehydrogenase, beta subunit; PFAM: coenzyme F420 hydrogenase/dehydrogenase beta subunit domain protein; SPTR: Putative uncharacterized protein; manually curated; PFAM: 4Fe-4S binding domain; Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus. | COGs: COG0667 oxidoreductase (related to aryl-alcohol dehydrogenase); InterPro IPR001395:IPR017896:IPR017900:IPR020471; KEGG: cth:Cthe_0152 aldo/keto reductase; PFAM: aldo/keto reductase; SPTR: Aldo/keto reductase; PFAM: Aldo/keto reductase family. | 0.838 |
| Toce_0228 | Toce_2213 | Toce_0228 | Toce_2213 | COGs: COG1035 Coenzyme F420-reducing hydrogenase beta subunit; InterPro IPR007525:IPR017900:IPR017896; KEGG: dps:DPPB80 related to F420H2-dehydrogenase, beta subunit; PFAM: coenzyme F420 hydrogenase/dehydrogenase beta subunit domain protein; SPTR: Putative uncharacterized protein; manually curated; PFAM: 4Fe-4S binding domain; Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus. | Nitrate reductase; COGs: COG0243 Anaerobic dehydrogenase typically selenocysteine-containing; InterPro IPR006655:IPR006963:IPR006656:IPR006657; KEGG: drm:Dred_1345 molybdopterin oxidoreductase; PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide-binding region; PRIAM: Nitrate reductase; SPTR: Molybdopterin oxidoreductase; PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain; Molybdopterin oxidoreductase Fe4S4 domain; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | 0.847 |
| Toce_0853 | Toce_1353 | Toce_0853 | Toce_1353 | COGs: COG0123 Deacetylase including yeast histone deacetylase and acetoin utilization protein; InterPro IPR000286; KEGG: tte:TTE1122 deacetylase; PFAM: histone deacetylase superfamily; SPTR: Deacetylases, including yeast histone deacetylase and acetoin utilization protein; PFAM: Histone deacetylase domain. | COGs: COG0667 oxidoreductase (related to aryl-alcohol dehydrogenase); InterPro IPR001395:IPR017896:IPR017900:IPR020471; KEGG: cth:Cthe_0152 aldo/keto reductase; PFAM: aldo/keto reductase; SPTR: Aldo/keto reductase; PFAM: Aldo/keto reductase family. | 0.782 |
| Toce_0853 | Toce_1494 | Toce_0853 | Toce_1494 | COGs: COG0123 Deacetylase including yeast histone deacetylase and acetoin utilization protein; InterPro IPR000286; KEGG: tte:TTE1122 deacetylase; PFAM: histone deacetylase superfamily; SPTR: Deacetylases, including yeast histone deacetylase and acetoin utilization protein; PFAM: Histone deacetylase domain. | KEGG: amt:Amet_4522 hypothetical protein; SPTR: Putative uncharacterized protein. | 0.649 |
| Toce_1146 | Toce_0086 | Toce_1146 | Toce_0086 | Conserved hypothetical protein; COGs: COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductase; InterPro IPR006058; KEGG: tex:Teth514_1576 hypothetical protein; SPTR: Oxidoreductase FAD-binding domain protein. | FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterPro IPR013027:IPR004017:IPR000759:IPR017900; KEGG: vpa:VP1199 putative glutamate synthase, small chain; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; protein of unknown function DUF224 cysteine-rich region domain protein; SPTR: Pyridine nucleotide-disulphide oxidoreductase family protein; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Cysteine-rich domain. | 0.922 |
| Toce_1146 | Toce_1353 | Toce_1146 | Toce_1353 | Conserved hypothetical protein; COGs: COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductase; InterPro IPR006058; KEGG: tex:Teth514_1576 hypothetical protein; SPTR: Oxidoreductase FAD-binding domain protein. | COGs: COG0667 oxidoreductase (related to aryl-alcohol dehydrogenase); InterPro IPR001395:IPR017896:IPR017900:IPR020471; KEGG: cth:Cthe_0152 aldo/keto reductase; PFAM: aldo/keto reductase; SPTR: Aldo/keto reductase; PFAM: Aldo/keto reductase family. | 0.686 |
| Toce_1146 | Toce_1494 | Toce_1146 | Toce_1494 | Conserved hypothetical protein; COGs: COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductase; InterPro IPR006058; KEGG: tex:Teth514_1576 hypothetical protein; SPTR: Oxidoreductase FAD-binding domain protein. | KEGG: amt:Amet_4522 hypothetical protein; SPTR: Putative uncharacterized protein. | 0.817 |
| Toce_1351 | Toce_1352 | Toce_1351 | Toce_1352 | Protein of unknown function DUF1292; InterPro IPR009711; KEGG: tte:TTE1251 hypothetical protein; PFAM: protein of unknown function DUF1292; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF1292); Belongs to the UPF0473 family. | Holliday junction resolvase YqgF; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. | 0.782 |
| Toce_1351 | Toce_1353 | Toce_1351 | Toce_1353 | Protein of unknown function DUF1292; InterPro IPR009711; KEGG: tte:TTE1251 hypothetical protein; PFAM: protein of unknown function DUF1292; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF1292); Belongs to the UPF0473 family. | COGs: COG0667 oxidoreductase (related to aryl-alcohol dehydrogenase); InterPro IPR001395:IPR017896:IPR017900:IPR020471; KEGG: cth:Cthe_0152 aldo/keto reductase; PFAM: aldo/keto reductase; SPTR: Aldo/keto reductase; PFAM: Aldo/keto reductase family. | 0.849 |
| Toce_1351 | Toce_1354 | Toce_1351 | Toce_1354 | Protein of unknown function DUF1292; InterPro IPR009711; KEGG: tte:TTE1251 hypothetical protein; PFAM: protein of unknown function DUF1292; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF1292); Belongs to the UPF0473 family. | Protein of unknown function DUF965; COGs: COG4472 conserved hypothetical protein; InterPro IPR009309; KEGG: dae:Dtox_2267 protein of unknown function DUF965; PFAM: protein of unknown function DUF965; SPTR: Putative uncharacterized protein; PFAM: Bacterial protein of unknown function (DUF965); Belongs to the UPF0297 family. | 0.664 |
| Toce_1351 | alaS | Toce_1351 | Toce_1355 | Protein of unknown function DUF1292; InterPro IPR009711; KEGG: tte:TTE1251 hypothetical protein; PFAM: protein of unknown function DUF1292; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF1292); Belongs to the UPF0473 family. | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | 0.521 |
| Toce_1352 | Toce_1351 | Toce_1352 | Toce_1351 | Holliday junction resolvase YqgF; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. | Protein of unknown function DUF1292; InterPro IPR009711; KEGG: tte:TTE1251 hypothetical protein; PFAM: protein of unknown function DUF1292; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF1292); Belongs to the UPF0473 family. | 0.782 |
| Toce_1352 | Toce_1353 | Toce_1352 | Toce_1353 | Holliday junction resolvase YqgF; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. | COGs: COG0667 oxidoreductase (related to aryl-alcohol dehydrogenase); InterPro IPR001395:IPR017896:IPR017900:IPR020471; KEGG: cth:Cthe_0152 aldo/keto reductase; PFAM: aldo/keto reductase; SPTR: Aldo/keto reductase; PFAM: Aldo/keto reductase family. | 0.829 |
| Toce_1352 | Toce_1354 | Toce_1352 | Toce_1354 | Holliday junction resolvase YqgF; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. | Protein of unknown function DUF965; COGs: COG4472 conserved hypothetical protein; InterPro IPR009309; KEGG: dae:Dtox_2267 protein of unknown function DUF965; PFAM: protein of unknown function DUF965; SPTR: Putative uncharacterized protein; PFAM: Bacterial protein of unknown function (DUF965); Belongs to the UPF0297 family. | 0.949 |
| Toce_1352 | alaS | Toce_1352 | Toce_1355 | Holliday junction resolvase YqgF; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | 0.884 |
| Toce_1353 | Toce_0086 | Toce_1353 | Toce_0086 | COGs: COG0667 oxidoreductase (related to aryl-alcohol dehydrogenase); InterPro IPR001395:IPR017896:IPR017900:IPR020471; KEGG: cth:Cthe_0152 aldo/keto reductase; PFAM: aldo/keto reductase; SPTR: Aldo/keto reductase; PFAM: Aldo/keto reductase family. | FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterPro IPR013027:IPR004017:IPR000759:IPR017900; KEGG: vpa:VP1199 putative glutamate synthase, small chain; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; protein of unknown function DUF224 cysteine-rich region domain protein; SPTR: Pyridine nucleotide-disulphide oxidoreductase family protein; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Cysteine-rich domain. | 0.677 |
| Toce_1353 | Toce_0228 | Toce_1353 | Toce_0228 | COGs: COG0667 oxidoreductase (related to aryl-alcohol dehydrogenase); InterPro IPR001395:IPR017896:IPR017900:IPR020471; KEGG: cth:Cthe_0152 aldo/keto reductase; PFAM: aldo/keto reductase; SPTR: Aldo/keto reductase; PFAM: Aldo/keto reductase family. | COGs: COG1035 Coenzyme F420-reducing hydrogenase beta subunit; InterPro IPR007525:IPR017900:IPR017896; KEGG: dps:DPPB80 related to F420H2-dehydrogenase, beta subunit; PFAM: coenzyme F420 hydrogenase/dehydrogenase beta subunit domain protein; SPTR: Putative uncharacterized protein; manually curated; PFAM: 4Fe-4S binding domain; Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus. | 0.838 |