STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Toce_1368COGs: COG1239 Mg-chelatase subunit ChlI; InterPro IPR003593; KEGG: sth:STH2441 putative chelatase; PRIAM: Magnesium chelatase; SMART: AAA ATPase; SPTR: Putative chelatase. (427 aa)    
Predicted Functional Partners:
Toce_1367
Von Willebrand factor type A; COGs: COG1240 Mg-chelatase subunit ChlD; InterPro IPR002035; KEGG: nth:Nther_2026 von Willebrand factor type A; PFAM: von Willebrand factor type A; SMART: von Willebrand factor type A; SPTR: Von Willebrand factor, type A; PFAM: von Willebrand factor type A domain.
 
 0.999
Toce_0251
COGs: COG0644 Dehydrogenase (flavoprotein); InterPro IPR003953:IPR003042; KEGG: nth:Nther_1774 FAD dependent oxidoreductase; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; SPTR: FAD dependent oxidoreductase; PFAM: FAD binding domain.
  
  
 0.769
Toce_1366
single-stranded-DNA-specific exonuclease RecJ; COGs: COG0608 Single-stranded DNA-specific exonuclease; InterPro IPR004610:IPR001667:IPR003156; KEGG: tte:TTE1191 single-stranded DNA-specific exonuclease; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; SPTR: Single-stranded-DNA-specific exonuclease RecJ; TIGRFAM: single-stranded-DNA-specific exonuclease RecJ; PFAM: DHH family; DHHA1 domain; TIGRFAM: single-stranded-DNA-specific exonuclease RecJ.
       0.582
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
       0.572
hemL
Glutamate-1-semialdehyde-2,1-aminomutase; COGs: COG0001 Glutamate-1-semialdehyde aminotransferase; InterPro IPR005814:IPR006367:IPR004639; KEGG: tex:Teth514_0321 glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; SPTR: Glutamate-1-semialdehyde-2,1-aminomutase; TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; siroheme synthase; PFAM: Aminotransferase class-III; TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; siroheme synthase, N-terminal domain; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
     
 0.562
Toce_1696
Glycosidase related protein; COGs: COG2152 glycosylase; InterPro IPR007184; KEGG: swo:Swol_1919 glycosylase-like protein; PFAM: glycosidase related protein; SPTR: Glycosylase-like protein; PFAM: Domain of unknown function (DUF377).
  
     0.550
Toce_1588
COGs: COG0438 Glycosyltransferase; InterProIPR001296:IPR013216:IPR001173:IPR019734:IPR 013026:IPR000276; KEGG: tnp:Tnap_0554 glycosyl transferase family 2; PFAM: glycosyl transferase family 2; Methyltransferase type 11; glycosyl transferase group 1; SMART: Tetratricopeptide repeat; SPTR: Glycosyl transferase family 2; PFAM: Methyltransferase domain; Glycosyl transferases group 1; Glycosyl transferase family 2.
 
  
 0.549
Toce_1364
(p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
       0.527
Toce_1369
Transposase IS4 family protein; COGs: COG3666 Transposase and inactivated derivatives; InterPro IPR002559; KEGG: tte:TTE2646 transposase; PFAM: transposase IS4 family protein; SPTR: Transposase; PFAM: Transposase DDE domain; Transposase domain (DUF772).
       0.522
Toce_1362
Beta-lactamase domain protein; COGs: COG0491 Zn-dependent hydrolase including glyoxylase; KEGG: dae:Dtox_2285 beta-lactamase domain protein; SPTR: Beta-lactamase domain protein; PFAM: Metallo-beta-lactamase superfamily.
  
    0.521
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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