STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
ruvBHolliday junction DNA helicase subunit RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (338 aa)    
Predicted Functional Partners:
ruvA
Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.
 
 
 0.999
ruvC
Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.
 
 
 0.987
Toce_1379
KEGG: tit:Thit_1007 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF2905).
  
    0.953
queA
S-adenosylmethionine--tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
  
  
 0.950
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
 
   
 0.848
Toce_1159
MCP methyltransferase, CheR-type; COGs: COG1352 Methylase of chemotaxis methyl-accepting protein; InterPro IPR000780; KEGG: amt:Amet_2623 protein-glutamate O-methyltransferase; PFAM: MCP methyltransferase CheR-type; PRIAM: Protein-glutamate O-methyltransferase; SMART: MCP methyltransferase CheR-type; SPTR: Protein-glutamate O-methyltransferase; PFAM: CheR methyltransferase, SAM binding domain; CheR methyltransferase, all-alpha domain.
    
   0.830
Toce_1378
SpoIID/LytB domain protein; COGs: COG2385 Sporulation protein and related protein; InterPro IPR013486:IPR013693; KEGG: tit:Thit_1008 SpoIID/LytB domain protein; PFAM: Stage II sporulation D domain protein; SPTR: SpoIID/LytB domain protein; TIGRFAM: SpoIID/LytB domain protein; PFAM: Stage II sporulation protein; TIGRFAM: SpoIID/LytB domain.
       0.819
tgt
tRNA-guanine transglycosylase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the [...]
  
    0.814
Toce_1376
KEGG: tpd:Teth39_0440 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.708
Toce_1374
COGs: COG1862 Preprotein translocase subunit YajC; InterPro IPR003849; KEGG: tte:TTE1184 preprotein translocase subunit YajC; PFAM: YajC family protein; SPTR: Preprotein translocase subunit YajC; TIGRFAM: preprotein translocase, YajC subunit; PFAM: Preprotein translocase subunit; TIGRFAM: preprotein translocase, YajC subunit.
  
  
 0.694
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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