Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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Toce_1387Spore cortex-lytic enzyme; COGs: COG3773 Cell wall hydrolyses involved in spore germination; InterPro IPR014224:IPR002477:IPR011105; KEGG: dhd:Dhaf_4849 spore cortex-lytic enzyme; PFAM: cell wall hydrolase SleB; Peptidoglycan-binding domain 1 protein; SPTR: Putative uncharacterized protein; TIGRFAM: spore cortex-lytic enzyme; PFAM: Putative peptidoglycan binding domain; Cell Wall Hydrolase; TIGRFAM: spore cortex-lytic enzyme. (228 aa)    
Predicted Functional Partners:
Toce_0758
Germination protein YpeB; InterPro IPR014239:IPR005075; KEGG: drm:Dred_3194 peptidase; PFAM: Propeptide PepSY amd peptidase M4; SPTR: Propeptide, PepSY amd peptidase M4; TIGRFAM: germination protein YpeB; TIGRFAM: germination protein YpeB.
 
  
 0.853
Toce_1263
InterPro IPR010894; KEGG: amt:Amet_2220 stage V sporulation protein AD; PFAM: Stage V sporulation AD family protein; SPTR: Stage V sporulation AD family protein; TIGRFAM: stage V sporulation protein AD; PFAM: Stage V sporulation protein AD (SpoVAD); TIGRFAM: stage V sporulation protein AD.
  
  
 0.568
Toce_1386
Protein of unknown function UPF0029; COGs: COG1739 conserved hypothetical protein; InterPro IPR015796:IPR001498:IPR015269; KEGG: cth:Cthe_2078 hypothetical protein; PFAM: protein of unknown function UPF0029; Domain of unknown function DUF1949; SPTR: Putative uncharacterized protein; PFAM: Uncharacterized protein family UPF0029; Domain of unknown function (DUF1949); TIGRFAM: conserved hypothetical protein TIGR00257.
       0.518
gpr
Spore protease; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family.
  
    0.507
Toce_1264
Stage V sporulation protein AC; InterPro IPR014203:IPR005562; KEGG: cdl:CDR20291_0702 stage V sporulation protein AC; PFAM: SpoVA protein; SPTR: Putative uncharacterized protein; TIGRFAM: stage V sporulation protein AC; PFAM: SpoVA protein; TIGRFAM: stage V sporulation protein AC.
  
  
 0.507
Toce_2202
InterPro IPR008844; KEGG: tit:Thit_2221 germination protein, Ger(X)C family; PFAM: spore germination B3 GerAC family protein; SPTR: Germination protein, Ger(X)C family; TIGRFAM: germination protein, Ger(x)C family; PFAM: Spore germination B3/ GerAC like, C-terminal; TIGRFAM: germination protein, Ger(x)C family.
 
  
 0.497
Toce_1142
Sporulation protein YtfJ; COGs: COG3874 conserved hypothetical protein; InterPro IPR014229; KEGG: tte:TTE1327 hypothetical protein; PFAM: Sporulation protein YtfJ; SPTR: Sporulation protein YtfJ; TIGRFAM: sporulation protein YtfJ; PFAM: Sporulation protein YtfJ (Spore_YtfJ); TIGRFAM: sporulation protein YtfJ.
  
  
 0.495
nadE
NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family.
       0.488
Toce_1013
Transcriptional regulator, TraR/DksA family; COGs: COG1734 DnaK suppressor protein; InterPro IPR000962:IPR020458:IPR014240; KEGG: hor:Hore_09300 transcriptional regulator, TraR/DksA family; PFAM: zinc finger DksA/TraR C4-type; SPTR: Transcriptional regulator, TraR/DksA family; TIGRFAM: sporulation protein, yteA family; PFAM: Prokaryotic dksA/traR C4-type zinc finger; TIGRFAM: sporulation protein, yteA family; RNA polymerase-binding protein DksA.
  
    0.432
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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