Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mutS2MutS2 family protein; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily. (790 aa)    
Predicted Functional Partners:
mutS
DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.
 
 
0.934
Toce_1394
PHP domain protein; COGs: COG1796 DNA polymerase IV (family X); InterProIPR004013:IPR002054:IPR003583:IPR003141:IPR 002008; KEGG: gbm:Gbem_0265 PHP domain protein; PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; DNA polymerase X; Helix-hairpin-helix DNA-binding class 1; SPTR: PHP domain protein; PFAM: PHP domain.
  
  
 0.883
Toce_1393
Peptidase U32; COGs: COG0826 Collagenase and related protease; InterPro IPR001539; KEGG: adg:Adeg_0544 peptidase U32; PFAM: peptidase U32; SPTR: Peptidase U32; PFAM: Collagenase; Peptidase family U32.
  
    0.826
Toce_1391
Protein of unknown function DUF523; COGs: COG1683 conserved hypothetical protein; InterPro IPR007553; KEGG: protein of unknown function DUF523; PFAM: protein of unknown function DUF523; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF523).
       0.812
Toce_1017
COGs: COG1293 RNA-binding protein homologous to eukaryotic snRNP; InterPro IPR008616:IPR008532; KEGG: tte:TTE1517 RNA-binding protein snRNP; PFAM: Fibronectin-binding A domain protein; protein of unknown function DUF814; SPTR: Predicted RNA-binding protein homologous to eukaryotic snRNP; PFAM: Domain of unknown function (DUF814); Fibronectin-binding protein A N-terminus (FbpA).
 
   
 0.795
rplB
LSU ribosomal protein L2P; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
  
 
   0.793
rplT
LSU ribosomal protein L20P; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.
   
   0.785
rpmI
LSU ribosomal protein L35P; InterPro IPR001706:IPR021137:IPR018265; KEGG: amt:Amet_1634 ribosomal protein L35; PFAM: Ribosomal protein L35; SPTR: 50S ribosomal protein L35; TIGRFAM: ribosomal protein L35; PFAM: Ribosomal protein L35; TIGRFAM: ribosomal protein L35; Belongs to the bacterial ribosomal protein bL35 family.
   
   0.785
rpmB
LSU ribosomal protein L28P; InterPro IPR001383; KEGG: dae:Dtox_1163 ribosomal protein L28; PFAM: ribosomal protein L28; SPTR: Ribosomal protein L28; TIGRFAM: ribosomal protein L28; PFAM: Ribosomal L28 family; TIGRFAM: ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family.
   
 
 0.778
rplM
LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
    
 
 0.776
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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