| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Toce_0321 | Toce_1010 | Toce_0321 | Toce_1010 | COGs: COG0007 Uroporphyrinogen-III methylase; InterPro IPR003043:IPR006366:IPR000878:IPR003754; KEGG: tex:Teth514_0319 uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; SPTR: Uroporphyrin-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin-III C-methyltransferase. | KEGG: tte:TTE1595 hypothetical protein; SPTR: Putative uncharacterized protein. | 0.403 |
| Toce_0321 | Toce_1151 | Toce_0321 | Toce_1151 | COGs: COG0007 Uroporphyrinogen-III methylase; InterPro IPR003043:IPR006366:IPR000878:IPR003754; KEGG: tex:Teth514_0319 uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; SPTR: Uroporphyrin-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin-III C-methyltransferase. | ABC transporter related protein; COGs: COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components; InterPro IPR003593:IPR020322:IPR003439:IPR017871; KEGG: hor:Hore_00190 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter related; PFAM: ABC transporter. | 0.403 |
| Toce_0321 | Toce_1422 | Toce_0321 | Toce_1422 | COGs: COG0007 Uroporphyrinogen-III methylase; InterPro IPR003043:IPR006366:IPR000878:IPR003754; KEGG: tex:Teth514_0319 uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; SPTR: Uroporphyrin-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin-III C-methyltransferase. | L-threonine-O-3-phosphate decarboxylase; COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterPro IPR005860:IPR004839:IPR004838; KEGG: cpe:CPE1040 threonine-phosphate decarboxylase; PFAM: aminotransferase class I and II; SPTR: Putative L-threonine-O-3-phosphate decarboxylase; TIGRFAM: L-threonine-O-3-phosphate decarboxylase; PFAM: Aminotransferase class I and II; TIGRFAM: L-threonine-O-3-phosphate decarboxylase; histidinol-phosphate aminotransferase. | 0.717 |
| Toce_0321 | Toce_1424 | Toce_0321 | Toce_1424 | COGs: COG0007 Uroporphyrinogen-III methylase; InterPro IPR003043:IPR006366:IPR000878:IPR003754; KEGG: tex:Teth514_0319 uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; SPTR: Uroporphyrin-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin-III C-methyltransferase. | Adenosylcobinamide-phosphateguanylyltransferase; COGs: COG2087 Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase; InterPro IPR003203; KEGG: aoe:Clos_2210 adenosylcobinamide-phosphate guanylyltransferase; PFAM: cobalbumin biosynthesis protein; PRIAM: Adenosylcobinamide-phosphate guanylyltransferase; SPTR: Adenosylcobinamide kinase; PFAM: Cobinamide kinase / cobinamide phosphate guanyltransferase. | 0.765 |
| Toce_0321 | Toce_1425 | Toce_0321 | Toce_1425 | COGs: COG0007 Uroporphyrinogen-III methylase; InterPro IPR003043:IPR006366:IPR000878:IPR003754; KEGG: tex:Teth514_0319 uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; SPTR: Uroporphyrin-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin-III C-methyltransferase. | COGs: COG0609 ABC-type Fe3+-siderophore transport system permease component; InterPro IPR000522; KEGG: aoe:Clos_0916 transport system permease protein; PFAM: transport system permease protein; SPTR: Transport system permease protein; PFAM: FecCD transport family; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. | 0.682 |
| Toce_0321 | Toce_1426 | Toce_0321 | Toce_1426 | COGs: COG0007 Uroporphyrinogen-III methylase; InterPro IPR003043:IPR006366:IPR000878:IPR003754; KEGG: tex:Teth514_0319 uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; SPTR: Uroporphyrin-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin-III C-methyltransferase. | Periplasmic binding protein; COGs: COG0614 ABC-type Fe3+-hydroxamate transport system periplasmic component; InterPro IPR002491; KEGG: dau:Daud_1317 periplasmic binding protein; PFAM: periplasmic binding protein; SPTR: Periplasmic binding protein; PFAM: Periplasmic binding protein. | 0.667 |
| Toce_0321 | cobD | Toce_0321 | Toce_1421 | COGs: COG0007 Uroporphyrinogen-III methylase; InterPro IPR003043:IPR006366:IPR000878:IPR003754; KEGG: tex:Teth514_0319 uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; SPTR: Uroporphyrin-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin-III C-methyltransferase. | Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.700 |
| Toce_0321 | cobS | Toce_0321 | Toce_1420 | COGs: COG0007 Uroporphyrinogen-III methylase; InterPro IPR003043:IPR006366:IPR000878:IPR003754; KEGG: tex:Teth514_0319 uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; SPTR: Uroporphyrin-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin-III C-methyltransferase. | Cobalamin 5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.699 |
| Toce_1010 | Toce_0321 | Toce_1010 | Toce_0321 | KEGG: tte:TTE1595 hypothetical protein; SPTR: Putative uncharacterized protein. | COGs: COG0007 Uroporphyrinogen-III methylase; InterPro IPR003043:IPR006366:IPR000878:IPR003754; KEGG: tex:Teth514_0319 uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; SPTR: Uroporphyrin-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin-III C-methyltransferase. | 0.403 |
| Toce_1010 | Toce_1425 | Toce_1010 | Toce_1425 | KEGG: tte:TTE1595 hypothetical protein; SPTR: Putative uncharacterized protein. | COGs: COG0609 ABC-type Fe3+-siderophore transport system permease component; InterPro IPR000522; KEGG: aoe:Clos_0916 transport system permease protein; PFAM: transport system permease protein; SPTR: Transport system permease protein; PFAM: FecCD transport family; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. | 0.926 |
| Toce_1010 | Toce_1426 | Toce_1010 | Toce_1426 | KEGG: tte:TTE1595 hypothetical protein; SPTR: Putative uncharacterized protein. | Periplasmic binding protein; COGs: COG0614 ABC-type Fe3+-hydroxamate transport system periplasmic component; InterPro IPR002491; KEGG: dau:Daud_1317 periplasmic binding protein; PFAM: periplasmic binding protein; SPTR: Periplasmic binding protein; PFAM: Periplasmic binding protein. | 0.846 |
| Toce_1151 | Toce_0321 | Toce_1151 | Toce_0321 | ABC transporter related protein; COGs: COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components; InterPro IPR003593:IPR020322:IPR003439:IPR017871; KEGG: hor:Hore_00190 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter related; PFAM: ABC transporter. | COGs: COG0007 Uroporphyrinogen-III methylase; InterPro IPR003043:IPR006366:IPR000878:IPR003754; KEGG: tex:Teth514_0319 uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; SPTR: Uroporphyrin-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin-III C-methyltransferase. | 0.403 |
| Toce_1151 | Toce_1425 | Toce_1151 | Toce_1425 | ABC transporter related protein; COGs: COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components; InterPro IPR003593:IPR020322:IPR003439:IPR017871; KEGG: hor:Hore_00190 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter related; PFAM: ABC transporter. | COGs: COG0609 ABC-type Fe3+-siderophore transport system permease component; InterPro IPR000522; KEGG: aoe:Clos_0916 transport system permease protein; PFAM: transport system permease protein; SPTR: Transport system permease protein; PFAM: FecCD transport family; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. | 0.995 |
| Toce_1151 | Toce_1426 | Toce_1151 | Toce_1426 | ABC transporter related protein; COGs: COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components; InterPro IPR003593:IPR020322:IPR003439:IPR017871; KEGG: hor:Hore_00190 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter related; PFAM: ABC transporter. | Periplasmic binding protein; COGs: COG0614 ABC-type Fe3+-hydroxamate transport system periplasmic component; InterPro IPR002491; KEGG: dau:Daud_1317 periplasmic binding protein; PFAM: periplasmic binding protein; SPTR: Periplasmic binding protein; PFAM: Periplasmic binding protein. | 0.979 |
| Toce_1422 | Toce_0321 | Toce_1422 | Toce_0321 | L-threonine-O-3-phosphate decarboxylase; COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterPro IPR005860:IPR004839:IPR004838; KEGG: cpe:CPE1040 threonine-phosphate decarboxylase; PFAM: aminotransferase class I and II; SPTR: Putative L-threonine-O-3-phosphate decarboxylase; TIGRFAM: L-threonine-O-3-phosphate decarboxylase; PFAM: Aminotransferase class I and II; TIGRFAM: L-threonine-O-3-phosphate decarboxylase; histidinol-phosphate aminotransferase. | COGs: COG0007 Uroporphyrinogen-III methylase; InterPro IPR003043:IPR006366:IPR000878:IPR003754; KEGG: tex:Teth514_0319 uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; SPTR: Uroporphyrin-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin-III C-methyltransferase. | 0.717 |
| Toce_1422 | Toce_1423 | Toce_1422 | Toce_1423 | L-threonine-O-3-phosphate decarboxylase; COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterPro IPR005860:IPR004839:IPR004838; KEGG: cpe:CPE1040 threonine-phosphate decarboxylase; PFAM: aminotransferase class I and II; SPTR: Putative L-threonine-O-3-phosphate decarboxylase; TIGRFAM: L-threonine-O-3-phosphate decarboxylase; PFAM: Aminotransferase class I and II; TIGRFAM: L-threonine-O-3-phosphate decarboxylase; histidinol-phosphate aminotransferase. | GHMP kinase; COGs: COG4542 Protein involved in propanediol utilization and related protein (includes coumermycin biosynthetic protein) possible kinase; InterPro IPR006204:IPR013750:IPR012363; KEGG: mta:Moth_1103 GHMP kinase; PFAM: GHMP kinase; GHMP kinase domain protein; SPTR: GHMP kinase; PFAM: GHMP kinases C terminal; GHMP kinases N terminal domain. | 0.987 |
| Toce_1422 | Toce_1424 | Toce_1422 | Toce_1424 | L-threonine-O-3-phosphate decarboxylase; COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterPro IPR005860:IPR004839:IPR004838; KEGG: cpe:CPE1040 threonine-phosphate decarboxylase; PFAM: aminotransferase class I and II; SPTR: Putative L-threonine-O-3-phosphate decarboxylase; TIGRFAM: L-threonine-O-3-phosphate decarboxylase; PFAM: Aminotransferase class I and II; TIGRFAM: L-threonine-O-3-phosphate decarboxylase; histidinol-phosphate aminotransferase. | Adenosylcobinamide-phosphateguanylyltransferase; COGs: COG2087 Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase; InterPro IPR003203; KEGG: aoe:Clos_2210 adenosylcobinamide-phosphate guanylyltransferase; PFAM: cobalbumin biosynthesis protein; PRIAM: Adenosylcobinamide-phosphate guanylyltransferase; SPTR: Adenosylcobinamide kinase; PFAM: Cobinamide kinase / cobinamide phosphate guanyltransferase. | 0.896 |
| Toce_1422 | Toce_1425 | Toce_1422 | Toce_1425 | L-threonine-O-3-phosphate decarboxylase; COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterPro IPR005860:IPR004839:IPR004838; KEGG: cpe:CPE1040 threonine-phosphate decarboxylase; PFAM: aminotransferase class I and II; SPTR: Putative L-threonine-O-3-phosphate decarboxylase; TIGRFAM: L-threonine-O-3-phosphate decarboxylase; PFAM: Aminotransferase class I and II; TIGRFAM: L-threonine-O-3-phosphate decarboxylase; histidinol-phosphate aminotransferase. | COGs: COG0609 ABC-type Fe3+-siderophore transport system permease component; InterPro IPR000522; KEGG: aoe:Clos_0916 transport system permease protein; PFAM: transport system permease protein; SPTR: Transport system permease protein; PFAM: FecCD transport family; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. | 0.681 |
| Toce_1422 | Toce_1426 | Toce_1422 | Toce_1426 | L-threonine-O-3-phosphate decarboxylase; COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterPro IPR005860:IPR004839:IPR004838; KEGG: cpe:CPE1040 threonine-phosphate decarboxylase; PFAM: aminotransferase class I and II; SPTR: Putative L-threonine-O-3-phosphate decarboxylase; TIGRFAM: L-threonine-O-3-phosphate decarboxylase; PFAM: Aminotransferase class I and II; TIGRFAM: L-threonine-O-3-phosphate decarboxylase; histidinol-phosphate aminotransferase. | Periplasmic binding protein; COGs: COG0614 ABC-type Fe3+-hydroxamate transport system periplasmic component; InterPro IPR002491; KEGG: dau:Daud_1317 periplasmic binding protein; PFAM: periplasmic binding protein; SPTR: Periplasmic binding protein; PFAM: Periplasmic binding protein. | 0.640 |
| Toce_1422 | cobD | Toce_1422 | Toce_1421 | L-threonine-O-3-phosphate decarboxylase; COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterPro IPR005860:IPR004839:IPR004838; KEGG: cpe:CPE1040 threonine-phosphate decarboxylase; PFAM: aminotransferase class I and II; SPTR: Putative L-threonine-O-3-phosphate decarboxylase; TIGRFAM: L-threonine-O-3-phosphate decarboxylase; PFAM: Aminotransferase class I and II; TIGRFAM: L-threonine-O-3-phosphate decarboxylase; histidinol-phosphate aminotransferase. | Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.996 |