Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Toce_1437COGs: COG4578 Glucitol operon activator; InterPro IPR009693; KEGG: cby:CLM_3883 glucitol operon activator protein; PFAM: Glucitol operon activator; SPTR: Glucitol operon activator protein; PFAM: Glucitol operon activator protein (GutM). (121 aa)    
Predicted Functional Partners:
Toce_1434
COGs: COG3731 Phosphotransferase system sorbitol-specific component IIA; InterPro IPR004716; KEGG: chl:Chy400_1450 PTS system glucitol/sorbitol-specific IIA component; PFAM: PTS system glucitol/sorbitol-specific IIA component; SPTR: PTS system glucitol/sorbitol-specific IIA component; PFAM: PTS system glucitol/sorbitol-specific IIA component.
 
  
 0.978
Toce_1436
PTS system, glucitol/sorbitol-specific, IIC subunit; COGs: COG3730 Phosphotransferase system sorbitol-specific component IIC; InterPro IPR004699; KEGG: bha:BH0771 PTS system, glucitol/sorbitol-specific enzyme II, C2 component (permease); PFAM: PTS system protein II sorbitol-specific factor; SPTR: PTS system, glucitol/sorbitol-specific enzyme II, C2 component (Permease); TIGRFAM: PTS system, glucitol/sorbitol-specific, IIC subunit; PFAM: PTS system enzyme II sorbitol-specific factor; TIGRFAM: PTS system, glucitol/sorbitol-specific, IIC component.
 
  
 0.974
Toce_1435
COGs: COG3732 Phosphotransferase system sorbitol-specific component IIBC; InterPro IPR011618:IPR011638; KEGG: bha:BH0772 PTS system, glucitol/sorbitol-specific enzyme II, BC component (EIIBC-GUT); PFAM: Sorbitol phosphotransferase protein II domain protein; PRIAM: Protein-N(pi)-phosphohistidine--sugar phosphotransferase; SPTR: PTS system, glucitol/sorbitol-specific enzyme II, BC component (EIIBC-GUT); PFAM: Sorbitol phosphotransferase enzyme II C-terminus; Sorbitol phosphotransferase enzyme II N-terminus; TIGRFAM: PTS system, glucitol/sorbitol-specific, IIBC component.
 
  
 0.970
Toce_1433
SAF domain protein; COGs: COG4091 homoserine dehydrogenase; InterPro IPR005106:IPR013974; KEGG: str:Sterm_3777 SAF domain protein; PFAM: SAF domain protein; homoserine dehydrogenase NAD-binding; SPTR: SAF domain protein; PFAM: Homoserine dehydrogenase, NAD binding domain; SAF domain.
 
     0.803
Toce_0054
Transcriptional antiterminator, BglG; COGs: COG3711 Transcriptional antiterminator; InterPro IPR011608:IPR002178:IPR013011; KEGG: amt:Amet_4270 transcriptional antiterminator, BglG; PFAM: PRD domain protein; PRIAM: Protein-N(pi)-phosphohistidine--sugar phosphotransferase; SPTR: Transcriptional antiterminator, BglG; PFAM: HTH domain; Mga helix-turn-helix domain; PTS system, Lactose/Cellobiose specific IIB subunit; PRD domain; Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2.
 
  
 0.727
Toce_1438
Transcriptional regulator, DeoR family; COGs: COG2390 Transcriptional regulator contains sigma factor-related N-terminal domain; InterPro IPR013249:IPR007324:IPR012318; KEGG: str:Sterm_3767 transcriptional regulator, DeoR family; PFAM: putative sugar-binding domain protein; Sigma-70 region 4 type 2; SPTR: Transcriptional regulator, DeoR family; PFAM: Sigma-70, region 4; Putative sugar-binding domain.
 
     0.715
Toce_1444
PTS system D-arabitol-specific IIC component, Gat family (TC 4.A.5.1.2); COGs: COG3775 Phosphotransferase system galactitol-specific IIC component; InterPro IPR013853:IPR004703:IPR013014; KEGG: cbe:Cbei_2500 PTS system galactitol-specific IIC component; PFAM: PTS system Galactitol-specific IIC component; SPTR: PTS system, galactitol-specific IIC subunit; TIGRFAM: PTS system, galactitol-specific IIC subunit; PFAM: PTS system sugar-specific permease component; TIGRFAM: PTS system, galactitol-specific IIC component.
 
     0.623
Toce_0264
Transcriptional antiterminator, BglG; COGs: COG3711 Transcriptional antiterminator; InterPro IPR007737:IPR011608:IPR002178:IPR013011; KEGG: cdf:CD3083 transcription antiterminator; PFAM: PRD domain protein; M trans-acting positive regulator; phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; PRIAM: Protein-N(pi)-phosphohistidine--sugar phosphotransferase; SPTR: Putative uncharacterized protein; PFAM: HTH domain; Mga helix-turn-helix domain; PRD domain; Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2.
 
  
 0.585
Toce_0541
Transcriptional antiterminator, BglG; COGs: COG3711 Transcriptional antiterminator; InterProIPR001034:IPR002178:IPR013011:IPR011608:IPR 007737; KEGG: tit:Thit_0523 PTS modulated transcriptional regulator, MtlR family; PFAM: PRD domain protein; M trans-acting positive regulator; phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; PRIAM: Protein-N(pi)-phosphohistidine--sugar phosphotransferase; SPTR: PTS modulated transcriptional regulator, MtlR family; PFAM: Mga helix-turn-helix domain; HTH domain; PRD domain; PTS system, Lactose/Cellobiose specific IIB subunit; Phosph [...]
 
  
 0.564
Toce_1986
Transcriptional antiterminator, BglG family; COGs: COG3711 Transcriptional antiterminator; InterPro IPR011608:IPR003501:IPR002178:IPR013011; KEGG: tex:Teth514_0531 transcriptional antiterminator, BglG; PFAM: PRD domain protein; phosphotransferase system lactose/cellobiose-specific IIB subunit; PRIAM: Protein-N(pi)-phosphohistidine--sugar phosphotransferase; SPTR: PTS modulated transcriptional regulator, MtlR family; PFAM: Mga helix-turn-helix domain; HTH domain; PTS system, Lactose/Cellobiose specific IIB subunit; PRD domain; Phosphoenolpyruvate-dependent sugar phosphotransferase syste [...]
 
  
 0.526
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.