Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Toce_1450COGs: COG1763 Molybdopterin-guanine dinucleotide biosynthesis protein; InterPro IPR004435; KEGG: dhd:Dhaf_4097 molybdopterin-guanine dinucleotide biosynthesis protein B; SPTR: Molybdopterin-guanine dinucleotide biosynthesis protein B; TIGRFAM: molybdopterin-guanine dinucleotide biosynthesis protein B; PFAM: Molybdopterin guanine dinucleotide synthesis protein B; TIGRFAM: molybdopterin-guanine dinucleotide biosynthesis protein MobB. (189 aa)    
Predicted Functional Partners:
mobA
Molybdenum cofactor guanylyltransferase; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
 
 
 0.818
Toce_0276
Molybdenum cofactor synthesis domain protein; COGs: COG0521 Molybdopterin biosynthesis protein; InterPro IPR020817:IPR005302:IPR001453:IPR008284; KEGG: ddf:DEFDS_0070 hypothetical protein; PFAM: molybdopterin binding domain; MOSC domain containing protein; SPTR: Putative uncharacterized protein; TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: MOSC domain; Probable molybdopterin binding domain; TIGRFAM: molybdenum cofactor synthesis domain.
 
 
 
 0.737
Toce_0785
NAD-dependent formate dehydrogenase catalytic subunit; COGs: COG3383 Uncharacterized anaerobic dehydrogenase; Contains selenocysteine; InterProIPR006478:IPR006655:IPR006963:IPR006656:IPR 006657; KEGG: nth:Nther_0100 formate dehydrogenase, alpha subunit; PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide-binding region; SPTR: Formate dehydrogenase, alpha subunit; TIGRFAM: formate dehydrogenase, alpha subunit; manually curated; PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain; Molybdopterin oxidoreductase F [...]
 
   
 0.684
Toce_0273
Molybdopterin molybdochelatase; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
 
 
 0.665
Toce_0272
Molybdopterin molybdochelatase; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
 
 
 0.629
Toce_2213
Nitrate reductase; COGs: COG0243 Anaerobic dehydrogenase typically selenocysteine-containing; InterPro IPR006655:IPR006963:IPR006656:IPR006657; KEGG: drm:Dred_1345 molybdopterin oxidoreductase; PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide-binding region; PRIAM: Nitrate reductase; SPTR: Molybdopterin oxidoreductase; PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain; Molybdopterin oxidoreductase Fe4S4 domain; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
 
   
 0.573
Toce_0045
KEGG: tpd:Teth39_0178 molybdopterin-guanine dinucleotide biosynthesis protein A-like protein; SPTR: Molybdopterin-guanine dinucleotide biosynthesis protein A-like protein; PFAM: Uncharacterized protein family UPF0007.
  
 
 0.556
Toce_1449
Transcriptional regulator, ArsR family; COGs: COG0640 transcriptional regulator protein; InterPro IPR001845:IPR018334; KEGG: tex:Teth514_1161 regulatory protein, ArsR; PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; SPTR: Regulatory protein, ArsR; PFAM: Bacterial regulatory protein, arsR family.
       0.547
uvrC
Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
       0.494
Toce_0382
Fe-S-cluster; COGs: COG0437 Fe-S-cluster-containing hydrogenase components 1; InterPro IPR017896:IPR017900; KEGG: pth:PTH_0486 Fe-S-cluster; SPTR: Fe-S-cluster; PFAM: 4Fe-4S binding domain.
 
     0.484
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
Server load: low (18%) [HD]