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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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Toce_1452Sigma54 specific transcriptional regulator with PAS/PAC sensor, Fis family; COGs: COG3829 Transcriptional regulator containing PAS AAA-type ATPase and DNA-binding domains; InterPro IPR013767:IPR002078:IPR002197:IPR003593; KEGG: drm:Dred_0663 putative PAS/PAC sensor protein; PFAM: sigma-54 factor interaction domain-containing protein; PAS fold domain protein; helix-turn-helix Fis-type; SMART: AAA ATPase; SPTR: Putative PAS/PAC sensor protein; PFAM: Bacterial regulatory protein, Fis family; Sigma-54 interaction domain; PAS fold. (515 aa)    
Predicted Functional Partners:
Toce_1856
COGs: COG1508 DNA-directed RNA polymerase specialized sigma subunit sigma54 homolog; InterPro IPR000394:IPR007046:IPR007634; KEGG: pth:PTH_2724 DNA-directed RNA polymerase specialized sigma subunit, sigma54-like protein; PFAM: sigma-54 DNA-binding domain protein; sigma-54 factor core-binding region; sigma-54 factor; SPTR: DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog; TIGRFAM: RNA polymerase sigma-54 factor, RpoN; PFAM: Sigma-54 factor, Activator interacting domain (AID); Sigma-54, DNA binding domain; Sigma-54 factor, core binding domain; TIGRFAM: RNA polymeras [...]
 
   
 0.791
Toce_1453
COGs: COG0686 Alanine dehydrogenase; InterPro IPR008141:IPR007886:IPR007698:IPR008143; KEGG: chy:CHY_0666 alanine dehydrogenase; PFAM: alanine dehydrogenase/PNT domain protein; SPTR: Alanine dehydrogenase; TIGRFAM: alanine dehydrogenase; PFAM: Alanine dehydrogenase/PNT, C-terminal domain; Alanine dehydrogenase/PNT, N-terminal domain; TIGRFAM: alanine dehydrogenase.
       0.484
Toce_1451
Amino acid carrier protein; COGs: COG1115 Na+/alanine symporter; InterPro IPR001463; KEGG: tex:Teth514_0910 amino acid carrier protein; PFAM: sodium:alanine symporter; SPTR: Amino acid carrier protein; TIGRFAM: amino acid carrier protein; PFAM: Sodium:alanine symporter family; TIGRFAM: amino acid carrier protein.
       0.419
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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