| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Toce_0276 | Toce_1466 | Toce_0276 | Toce_1466 | Molybdenum cofactor synthesis domain protein; COGs: COG0521 Molybdopterin biosynthesis protein; InterPro IPR020817:IPR005302:IPR001453:IPR008284; KEGG: ddf:DEFDS_0070 hypothetical protein; PFAM: molybdopterin binding domain; MOSC domain containing protein; SPTR: Putative uncharacterized protein; TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: MOSC domain; Probable molybdopterin binding domain; TIGRFAM: molybdenum cofactor synthesis domain. | Putative transcriptional regulator, ModE family; COGs: COG2005 N-terminal domain of molybdenum-binding protein; InterPro IPR000847; KEGG: mta:Moth_0066 ModE family transcriptional regulator; PFAM: regulatory protein LysR; SPTR: Transcriptional regulator, ModE family; PFAM: Bacterial regulatory helix-turn-helix protein, lysR family; TIGRFAM: ModE molybdate transport repressor domain. | 0.550 |
| Toce_0276 | moaA | Toce_0276 | Toce_0274 | Molybdenum cofactor synthesis domain protein; COGs: COG0521 Molybdopterin biosynthesis protein; InterPro IPR020817:IPR005302:IPR001453:IPR008284; KEGG: ddf:DEFDS_0070 hypothetical protein; PFAM: molybdopterin binding domain; MOSC domain containing protein; SPTR: Putative uncharacterized protein; TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: MOSC domain; Probable molybdopterin binding domain; TIGRFAM: molybdenum cofactor synthesis domain. | GTP cyclohydrolase subunit MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | 0.991 |
| Toce_1462 | Toce_1465 | Toce_1462 | Toce_1465 | Cobalamin B12-binding domain protein; COGs: COG1032 Fe-S oxidoreductase; InterPro IPR006158:IPR007197:IPR006638; KEGG: tpd:Teth39_0963 radical SAM domain-containing protein; PFAM: cobalamin B12-binding domain protein; Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein; PFAM: Radical SAM superfamily; B12 binding domain. | Aminotransferase class V; COGs: COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase; InterPro IPR000192:IPR016454:IPR020578; KEGG: tte:TTE1663 cysteine sulfinate desulfinase/cysteine desulfurase; PFAM: aminotransferase class V; SPTR: Aminotransferase class V; PFAM: Aminotransferase class-V. | 0.611 |
| Toce_1462 | Toce_1466 | Toce_1462 | Toce_1466 | Cobalamin B12-binding domain protein; COGs: COG1032 Fe-S oxidoreductase; InterPro IPR006158:IPR007197:IPR006638; KEGG: tpd:Teth39_0963 radical SAM domain-containing protein; PFAM: cobalamin B12-binding domain protein; Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein; PFAM: Radical SAM superfamily; B12 binding domain. | Putative transcriptional regulator, ModE family; COGs: COG2005 N-terminal domain of molybdenum-binding protein; InterPro IPR000847; KEGG: mta:Moth_0066 ModE family transcriptional regulator; PFAM: regulatory protein LysR; SPTR: Transcriptional regulator, ModE family; PFAM: Bacterial regulatory helix-turn-helix protein, lysR family; TIGRFAM: ModE molybdate transport repressor domain. | 0.573 |
| Toce_1462 | aroE | Toce_1462 | Toce_1463 | Cobalamin B12-binding domain protein; COGs: COG1032 Fe-S oxidoreductase; InterPro IPR006158:IPR007197:IPR006638; KEGG: tpd:Teth39_0963 radical SAM domain-containing protein; PFAM: cobalamin B12-binding domain protein; Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein; PFAM: Radical SAM superfamily; B12 binding domain. | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.727 |
| Toce_1462 | thiI | Toce_1462 | Toce_1464 | Cobalamin B12-binding domain protein; COGs: COG1032 Fe-S oxidoreductase; InterPro IPR006158:IPR007197:IPR006638; KEGG: tpd:Teth39_0963 radical SAM domain-containing protein; PFAM: cobalamin B12-binding domain protein; Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein; PFAM: Radical SAM superfamily; B12 binding domain. | Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.619 |
| Toce_1465 | Toce_1462 | Toce_1465 | Toce_1462 | Aminotransferase class V; COGs: COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase; InterPro IPR000192:IPR016454:IPR020578; KEGG: tte:TTE1663 cysteine sulfinate desulfinase/cysteine desulfurase; PFAM: aminotransferase class V; SPTR: Aminotransferase class V; PFAM: Aminotransferase class-V. | Cobalamin B12-binding domain protein; COGs: COG1032 Fe-S oxidoreductase; InterPro IPR006158:IPR007197:IPR006638; KEGG: tpd:Teth39_0963 radical SAM domain-containing protein; PFAM: cobalamin B12-binding domain protein; Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein; PFAM: Radical SAM superfamily; B12 binding domain. | 0.611 |
| Toce_1465 | Toce_1466 | Toce_1465 | Toce_1466 | Aminotransferase class V; COGs: COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase; InterPro IPR000192:IPR016454:IPR020578; KEGG: tte:TTE1663 cysteine sulfinate desulfinase/cysteine desulfurase; PFAM: aminotransferase class V; SPTR: Aminotransferase class V; PFAM: Aminotransferase class-V. | Putative transcriptional regulator, ModE family; COGs: COG2005 N-terminal domain of molybdenum-binding protein; InterPro IPR000847; KEGG: mta:Moth_0066 ModE family transcriptional regulator; PFAM: regulatory protein LysR; SPTR: Transcriptional regulator, ModE family; PFAM: Bacterial regulatory helix-turn-helix protein, lysR family; TIGRFAM: ModE molybdate transport repressor domain. | 0.725 |
| Toce_1465 | aroE | Toce_1465 | Toce_1463 | Aminotransferase class V; COGs: COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase; InterPro IPR000192:IPR016454:IPR020578; KEGG: tte:TTE1663 cysteine sulfinate desulfinase/cysteine desulfurase; PFAM: aminotransferase class V; SPTR: Aminotransferase class V; PFAM: Aminotransferase class-V. | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.659 |
| Toce_1465 | thiI | Toce_1465 | Toce_1464 | Aminotransferase class V; COGs: COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase; InterPro IPR000192:IPR016454:IPR020578; KEGG: tte:TTE1663 cysteine sulfinate desulfinase/cysteine desulfurase; PFAM: aminotransferase class V; SPTR: Aminotransferase class V; PFAM: Aminotransferase class-V. | Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.994 |
| Toce_1466 | Toce_0276 | Toce_1466 | Toce_0276 | Putative transcriptional regulator, ModE family; COGs: COG2005 N-terminal domain of molybdenum-binding protein; InterPro IPR000847; KEGG: mta:Moth_0066 ModE family transcriptional regulator; PFAM: regulatory protein LysR; SPTR: Transcriptional regulator, ModE family; PFAM: Bacterial regulatory helix-turn-helix protein, lysR family; TIGRFAM: ModE molybdate transport repressor domain. | Molybdenum cofactor synthesis domain protein; COGs: COG0521 Molybdopterin biosynthesis protein; InterPro IPR020817:IPR005302:IPR001453:IPR008284; KEGG: ddf:DEFDS_0070 hypothetical protein; PFAM: molybdopterin binding domain; MOSC domain containing protein; SPTR: Putative uncharacterized protein; TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: MOSC domain; Probable molybdopterin binding domain; TIGRFAM: molybdenum cofactor synthesis domain. | 0.550 |
| Toce_1466 | Toce_1462 | Toce_1466 | Toce_1462 | Putative transcriptional regulator, ModE family; COGs: COG2005 N-terminal domain of molybdenum-binding protein; InterPro IPR000847; KEGG: mta:Moth_0066 ModE family transcriptional regulator; PFAM: regulatory protein LysR; SPTR: Transcriptional regulator, ModE family; PFAM: Bacterial regulatory helix-turn-helix protein, lysR family; TIGRFAM: ModE molybdate transport repressor domain. | Cobalamin B12-binding domain protein; COGs: COG1032 Fe-S oxidoreductase; InterPro IPR006158:IPR007197:IPR006638; KEGG: tpd:Teth39_0963 radical SAM domain-containing protein; PFAM: cobalamin B12-binding domain protein; Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein; PFAM: Radical SAM superfamily; B12 binding domain. | 0.573 |
| Toce_1466 | Toce_1465 | Toce_1466 | Toce_1465 | Putative transcriptional regulator, ModE family; COGs: COG2005 N-terminal domain of molybdenum-binding protein; InterPro IPR000847; KEGG: mta:Moth_0066 ModE family transcriptional regulator; PFAM: regulatory protein LysR; SPTR: Transcriptional regulator, ModE family; PFAM: Bacterial regulatory helix-turn-helix protein, lysR family; TIGRFAM: ModE molybdate transport repressor domain. | Aminotransferase class V; COGs: COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase; InterPro IPR000192:IPR016454:IPR020578; KEGG: tte:TTE1663 cysteine sulfinate desulfinase/cysteine desulfurase; PFAM: aminotransferase class V; SPTR: Aminotransferase class V; PFAM: Aminotransferase class-V. | 0.725 |
| Toce_1466 | aroE | Toce_1466 | Toce_1463 | Putative transcriptional regulator, ModE family; COGs: COG2005 N-terminal domain of molybdenum-binding protein; InterPro IPR000847; KEGG: mta:Moth_0066 ModE family transcriptional regulator; PFAM: regulatory protein LysR; SPTR: Transcriptional regulator, ModE family; PFAM: Bacterial regulatory helix-turn-helix protein, lysR family; TIGRFAM: ModE molybdate transport repressor domain. | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.607 |
| Toce_1466 | moaA | Toce_1466 | Toce_0274 | Putative transcriptional regulator, ModE family; COGs: COG2005 N-terminal domain of molybdenum-binding protein; InterPro IPR000847; KEGG: mta:Moth_0066 ModE family transcriptional regulator; PFAM: regulatory protein LysR; SPTR: Transcriptional regulator, ModE family; PFAM: Bacterial regulatory helix-turn-helix protein, lysR family; TIGRFAM: ModE molybdate transport repressor domain. | GTP cyclohydrolase subunit MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | 0.419 |
| Toce_1466 | thiI | Toce_1466 | Toce_1464 | Putative transcriptional regulator, ModE family; COGs: COG2005 N-terminal domain of molybdenum-binding protein; InterPro IPR000847; KEGG: mta:Moth_0066 ModE family transcriptional regulator; PFAM: regulatory protein LysR; SPTR: Transcriptional regulator, ModE family; PFAM: Bacterial regulatory helix-turn-helix protein, lysR family; TIGRFAM: ModE molybdate transport repressor domain. | Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.723 |
| aroE | Toce_1462 | Toce_1463 | Toce_1462 | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | Cobalamin B12-binding domain protein; COGs: COG1032 Fe-S oxidoreductase; InterPro IPR006158:IPR007197:IPR006638; KEGG: tpd:Teth39_0963 radical SAM domain-containing protein; PFAM: cobalamin B12-binding domain protein; Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein; PFAM: Radical SAM superfamily; B12 binding domain. | 0.727 |
| aroE | Toce_1465 | Toce_1463 | Toce_1465 | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | Aminotransferase class V; COGs: COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase; InterPro IPR000192:IPR016454:IPR020578; KEGG: tte:TTE1663 cysteine sulfinate desulfinase/cysteine desulfurase; PFAM: aminotransferase class V; SPTR: Aminotransferase class V; PFAM: Aminotransferase class-V. | 0.659 |
| aroE | Toce_1466 | Toce_1463 | Toce_1466 | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | Putative transcriptional regulator, ModE family; COGs: COG2005 N-terminal domain of molybdenum-binding protein; InterPro IPR000847; KEGG: mta:Moth_0066 ModE family transcriptional regulator; PFAM: regulatory protein LysR; SPTR: Transcriptional regulator, ModE family; PFAM: Bacterial regulatory helix-turn-helix protein, lysR family; TIGRFAM: ModE molybdate transport repressor domain. | 0.607 |
| aroE | thiI | Toce_1463 | Toce_1464 | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.674 |