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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Toce_1472Formimidoyltetrahydrofolate cyclodeaminase; COGs: COG3404 Methenyl tetrahydrofolate cyclohydrolase; InterPro IPR007044; KEGG: dtu:Dtur_0698 formiminotransferase-cyclodeaminase; PFAM: Formiminotransferase-cyclodeaminase; SPTR: Formiminotransferase-cyclodeaminase; PFAM: Formiminotransferase-cyclodeaminase. (209 aa)    
Predicted Functional Partners:
Toce_1474
COGs: COG3643 Glutamate formiminotransferase; InterPro IPR004227:IPR012886:IPR013802; KEGG: sds:SDEG_2057 glutamate formiminotransferase; PFAM: Formiminotransferase domain protein; Formiminotransferase domain protein; PRIAM: Glutamate formimidoyltransferase; SPTR: Glutamate formiminotransferase; TIGRFAM: glutamate formiminotransferase; PFAM: Formiminotransferase domain, N-terminal subdomain; Formiminotransferase domain; TIGRFAM: glutamate formiminotransferase.
 
  0.999
folD
5,10-methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
   
 0.947
fhs
Formate-tetrahydrofolate ligase; COGs: COG2759 Formyltetrahydrofolate synthetase; InterPro IPR020628:IPR000559; KEGG: ckr:CKR_0385 hypothetical protein; PFAM: formate-tetrahydrofolate ligase FTHFS; PRIAM: Formate--tetrahydrofolate ligase; SPTR: Formate--tetrahydrofolate ligase; PFAM: Formate--tetrahydrofolate ligase.
    
 0.939
Toce_0352
COGs: COG0212 5-formyltetrahydrofolate cyclo-ligase; InterPro IPR002698; KEGG: chy:CHY_0730 5-formyltetrahydrofolate cyclo-ligase family protein; PFAM: 5-formyltetrahydrofolate cyclo-ligase; SPTR: 5-formyltetrahydrofolate cyclo-ligase family protein; TIGRFAM: 5-formyltetrahydrofolate cyclo-ligase; PFAM: 5-formyltetrahydrofolate cyclo-ligase family; TIGRFAM: 5,10-methenyltetrahydrofolate synthetase.
    
  0.907
Toce_0804
Formimidoyltetrahydrofolate cyclodeaminase; COGs: COG3404 Methenyl tetrahydrofolate cyclohydrolase; InterPro IPR007044; KEGG: cdf:CD0719 methenyltetrahydrofolate cyclohydrolase; PFAM: Formiminotransferase-cyclodeaminase; PRIAM: Glutamate formimidoyltransferase; SPTR: Methenyltetrahydrofolate cyclohydrolase; PFAM: Formiminotransferase-cyclodeaminase.
  
  
 
0.905
purH
IMP cyclohydrolase; COGs: COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful); InterPro IPR002695:IPR011607:IPR013982; KEGG: tte:TTE0592 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: AICARFT/IMPCHase bienzyme formylation region; MGS domain protein; PRIAM: Phosphoribosylaminoimidazolecarboxamide formyltransferase; SMART: AICARFT/IMPCHase bienzyme formylation region; SPTR: Bifunctional purine biosynthesis protein PurH; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohy [...]
    
 0.903
purN
Formyltetrahydrofolate-dependent phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
     
  0.900
hutI
COGs: COG1228 Imidazolonepropionase and related amidohydrolase; InterPro IPR005920:IPR006680; KEGG: hutI; imidazolonepropionase; PFAM: amidohydrolase; SPTR: Imidazolonepropionase; TIGRFAM: imidazolonepropionase; PFAM: Amidohydrolase family; TIGRFAM: imidazolonepropionase; Belongs to the metallo-dependent hydrolases superfamily. HutI family.
 
    0.707
hutH
COGs: COG2986 Histidine ammonia-lyase; InterPro IPR005921:IPR001106; KEGG: tpd:Teth39_1488 histidine ammonia-lyase; PFAM: phenylalanine/histidine ammonia-lyase; PRIAM: Histidine ammonia-lyase; SPTR: Histidine ammonia-lyase; TIGRFAM: histidine ammonia-lyase; PFAM: Phenylalanine and histidine ammonia-lyase; TIGRFAM: phenylalanine ammonia-lyase; histidine ammonia-lyase.
 
  
 0.667
hutU
Urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate.
       0.581
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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