Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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co-expression
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gene co-occurrence
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Toce_1480Export-related chaperone CsaA; COGs: COG0073 EMAP domain; InterPro IPR008231:IPR002547; KEGG: bmq:BMQ_pBM50063 export-related chaperone CsaA; PFAM: t-RNA-binding domain protein; SPTR: Export-related chaperone CsaA; TIGRFAM: export-related chaperone CsaA; PFAM: Putative tRNA binding domain; TIGRFAM: methionyl-tRNA synthetase C-terminal region/beta chain; export-related chaperone CsaA. (109 aa)    
Predicted Functional Partners:
pheS
COGs: COG0016 Phenylalanyl-tRNA synthetase alpha subunit; InterPro IPR004529:IPR004188:IPR002319:IPR006195; KEGG: tpd:Teth39_0771 phenylalanyl-tRNA synthetase subunit alpha; PFAM: phenylalanyl-tRNA synthetase class IIc; aminoacyl tRNA synthetase class II domain protein; SPTR: Phenylalanyl-tRNA synthetase, alpha subunit; TIGRFAM: phenylalanyl-tRNA synthetase, alpha subunit; PFAM: tRNA synthetases class II core domain (F); Aminoacyl tRNA synthetase class II, N-terminal domain; TIGRFAM: phenylalanyl-tRNA synthetase, alpha subunit; Belongs to the class-II aminoacyl-tRNA synthetase family. [...]
  
 
 0.924
Toce_1481
Transcriptional regulator, LysR family; COGs: COG0583 Transcriptional regulator; InterPro IPR000847:IPR005119; KEGG: dhd:Dhaf_1115 transcriptional regulator, LysR family; PFAM: LysR substrate-binding; regulatory protein LysR; SPTR: Transcriptional regulator, LysR family; PFAM: Bacterial regulatory helix-turn-helix protein, lysR family; LysR substrate binding domain.
       0.671
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
  
 0.663
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
  
  
 0.550
sspI
InterPro IPR017525; KEGG: tpd:Teth39_0969 small acid-soluble spore protein SspI; SPTR: Small, acid-soluble spore protein I; TIGRFAM: small, acid-soluble spore protein I; TIGRFAM: small, acid-soluble spore protein I; Belongs to the SspI family.
       0.539
rny
Metal dependent phosphohydrolase; Endoribonuclease that initiates mRNA decay. Belongs to the RNase Y family.
  
  
 0.529
ispH
Hydroxymethylbutenyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.
  
  
 0.526
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.509
sfsA
COGs: COG1489 DNA-binding protein stimulates sugar fermentation; InterPro IPR005224; KEGG: cbi:CLJ_B0041 sugar fermentation stimulation protein; PFAM: sugar fermentation stimulation protein; SPTR: Sugar fermentation stimulation protein; TIGRFAM: sugar fermentation stimulation protein; PFAM: Sugar fermentation stimulation protein; TIGRFAM: sugar fermentation stimulation protein; Belongs to the SfsA family.
       0.486
Toce_1483
KEGG: hor:Hore_09920 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.477
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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