Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
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[Homology]
Score
Toce_1487Pyridoxal-5'-phosphate-dependent protein beta subunit; COGs: COG0031 Cysteine synthase; InterPro IPR001926; KEGG: tte:TTE1236 threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: Threonine synthase; PFAM: Pyridoxal-phosphate dependent enzyme. (472 aa)    
Predicted Functional Partners:
Toce_1489
Dihydrodipicolinate reductase; COGs: COG3804 conserved hypothetical protein related to dihydrodipicolinate reductase; InterPro IPR000846; KEGG: tte:TTE1234 hypothetical protein; PFAM: dihydrodipicolinate reductase; SPTR: Putative uncharacterized protein; PFAM: Dihydrodipicolinate reductase, N-terminus.
 
   
 0.960
Toce_1488
KEGG: taf:THA_1161 hypothetical protein; SPTR: Putative uncharacterized protein.
 
     0.955
Toce_1485
D-ornithine 4,5-aminomutase E subunit; COGs: COG5012 cobalamin binding protein; InterPro IPR015130:IPR006158; KEGG: tte:TTE1238 methylmalonyl-CoA mutase C-terminal domain-containing protein; PFAM: cobalamin B12-binding domain protein; D-Lysine 56-aminomutase alpha subunit; SPTR: Methylmalonyl-CoA mutase, C-terminal domain/subunit (Cobalamin-binding); PFAM: D-Lysine 5,6-aminomutase alpha subunit; B12 binding domain; TIGRFAM: methylmalonyl-CoA mutase C-terminal domain.
 
   
 0.953
Toce_1486
D-ornithine 4,5-aminomutase S subunit; KEGG: hor:Hore_21080 hypothetical protein; SPTR: Putative uncharacterized protein.
 
     0.952
Toce_1484
Methylaspartate mutase; InterPro IPR006230; KEGG: amt:Amet_2372 methylaspartate mutase; SPTR: Methylaspartate mutase; TIGRFAM: conserved hypothetical protein.
 
     0.944
Toce_1491
Alanine racemase domain protein; COGs: COG3457 amino acid racemase; InterPro IPR001608; KEGG: hor:Hore_19150 alanine racemase domain protein; PFAM: alanine racemase domain protein; SPTR: Amino acid racemase; PFAM: Alanine racemase, N-terminal domain.
 
   
 0.859
Toce_2115
COGs: COG1045 Serine acetyltransferase; InterPro IPR005881:IPR001451; KEGG: chy:CHY_2339 serine acetyltransferase; SPTR: Serine O-acetyltransferase; TIGRFAM: serine O-acetyltransferase; PFAM: Serine acetyltransferase, N-terminal; Bacterial transferase hexapeptide (three repeats); TIGRFAM: serine O-acetyltransferase.
  
 
 0.798
Toce_0712
COGs: COG0626 Cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR000358:IPR000277; KEGG: gwc:GWCH70_2474 cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; SPTR: Cystathionine gamma-synthase; PFAM: Cys/Met metabolism PLP-dependent enzyme; TIGRFAM: cystathionine beta-lyase, eukaryotic.
  
 
 0.678
Toce_1559
Methionine gamma-lyase; COGs: COG0626 Cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR006237:IPR000277; KEGG: cko:CKO_04984 hypothetical protein; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; SPTR: Methionine gamma-lyase; TIGRFAM: methionine gamma-lyase; PFAM: Cys/Met metabolism PLP-dependent enzyme; TIGRFAM: methionine gamma-lyase; O-succinylhomoserine sulfhydrylase.
  
 
 0.678
hemL
Glutamate-1-semialdehyde-2,1-aminomutase; COGs: COG0001 Glutamate-1-semialdehyde aminotransferase; InterPro IPR005814:IPR006367:IPR004639; KEGG: tex:Teth514_0321 glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; SPTR: Glutamate-1-semialdehyde-2,1-aminomutase; TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; siroheme synthase; PFAM: Aminotransferase class-III; TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; siroheme synthase, N-terminal domain; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
  
  
 0.591
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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