Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Toce_1491Alanine racemase domain protein; COGs: COG3457 amino acid racemase; InterPro IPR001608; KEGG: hor:Hore_19150 alanine racemase domain protein; PFAM: alanine racemase domain protein; SPTR: Amino acid racemase; PFAM: Alanine racemase, N-terminal domain. (355 aa)    
Predicted Functional Partners:
Toce_1485
D-ornithine 4,5-aminomutase E subunit; COGs: COG5012 cobalamin binding protein; InterPro IPR015130:IPR006158; KEGG: tte:TTE1238 methylmalonyl-CoA mutase C-terminal domain-containing protein; PFAM: cobalamin B12-binding domain protein; D-Lysine 56-aminomutase alpha subunit; SPTR: Methylmalonyl-CoA mutase, C-terminal domain/subunit (Cobalamin-binding); PFAM: D-Lysine 5,6-aminomutase alpha subunit; B12 binding domain; TIGRFAM: methylmalonyl-CoA mutase C-terminal domain.
 
  
 0.985
Toce_1486
D-ornithine 4,5-aminomutase S subunit; KEGG: hor:Hore_21080 hypothetical protein; SPTR: Putative uncharacterized protein.
 
  
  0.985
Toce_0848
D-amino acid aminotransferase; Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha-keto acid in the first half-reaction.
     
  0.900
Toce_1488
KEGG: taf:THA_1161 hypothetical protein; SPTR: Putative uncharacterized protein.
 
   
 0.861
Toce_1487
Pyridoxal-5'-phosphate-dependent protein beta subunit; COGs: COG0031 Cysteine synthase; InterPro IPR001926; KEGG: tte:TTE1236 threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: Threonine synthase; PFAM: Pyridoxal-phosphate dependent enzyme.
 
   
 0.859
Toce_1489
Dihydrodipicolinate reductase; COGs: COG3804 conserved hypothetical protein related to dihydrodipicolinate reductase; InterPro IPR000846; KEGG: tte:TTE1234 hypothetical protein; PFAM: dihydrodipicolinate reductase; SPTR: Putative uncharacterized protein; PFAM: Dihydrodipicolinate reductase, N-terminus.
 
   
 0.841
Toce_1484
Methylaspartate mutase; InterPro IPR006230; KEGG: amt:Amet_2372 methylaspartate mutase; SPTR: Methylaspartate mutase; TIGRFAM: conserved hypothetical protein.
 
     0.831
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
     
  0.800
Toce_1492
PAS modulated sigma54 specific transcriptional regulator, Fis family; COGs: COG3829 Transcriptional regulator containing PAS AAA-type ATPase and DNA-binding domains; InterProIPR000014:IPR013656:IPR002078:IPR002197:IPR 003593:IPR020441; KEGG: amt:Amet_2366 sigma-54 dependent trancsriptional regulator; PFAM: sigma-54 factor interaction domain-containing protein; PAS fold-4 domain protein; helix-turn-helix Fis-type; SMART: AAA ATPase; PAS domain containing protein; SPTR: Sigma54 specific transcriptional regulator, Fis family; TIGRFAM: PAS sensor protein; PFAM: Bacterial regulatory protein [...]
       0.661
Toce_1493
Protein of unknown function DUF1284; COGs: COG3543 conserved hypothetical protein; InterPro IPR009702; KEGG: adg:Adeg_0990 protein of unknown function DUF1284; PFAM: protein of unknown function DUF1284; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF1284).
       0.612
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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