Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Toce_1493Protein of unknown function DUF1284; COGs: COG3543 conserved hypothetical protein; InterPro IPR009702; KEGG: adg:Adeg_0990 protein of unknown function DUF1284; PFAM: protein of unknown function DUF1284; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF1284). (125 aa)    
Predicted Functional Partners:
Toce_1494
KEGG: amt:Amet_4522 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.773
Toce_1492
PAS modulated sigma54 specific transcriptional regulator, Fis family; COGs: COG3829 Transcriptional regulator containing PAS AAA-type ATPase and DNA-binding domains; InterProIPR000014:IPR013656:IPR002078:IPR002197:IPR 003593:IPR020441; KEGG: amt:Amet_2366 sigma-54 dependent trancsriptional regulator; PFAM: sigma-54 factor interaction domain-containing protein; PAS fold-4 domain protein; helix-turn-helix Fis-type; SMART: AAA ATPase; PAS domain containing protein; SPTR: Sigma54 specific transcriptional regulator, Fis family; TIGRFAM: PAS sensor protein; PFAM: Bacterial regulatory protein [...]
       0.714
Toce_1491
Alanine racemase domain protein; COGs: COG3457 amino acid racemase; InterPro IPR001608; KEGG: hor:Hore_19150 alanine racemase domain protein; PFAM: alanine racemase domain protein; SPTR: Amino acid racemase; PFAM: Alanine racemase, N-terminal domain.
       0.612
Toce_1495
Polynucleotide adenylyltransferase/metal dependent phosphohydrolase; COGs: COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; InterPro IPR002646:IPR006674; KEGG: bhy:BHWA1_01411 polyA polymerase; PFAM: Polynucleotide adenylyltransferase region; metal-dependent phosphohydrolase HD sub domain; SPTR: Uncharacterized domain HDIG-containing protein; PFAM: HD domain; Poly A polymerase head domain.
       0.557
Toce_1496
Phosphodiesterase, MJ0936 family; COGs: COG0622 phosphoesterase; InterPro IPR000979:IPR004843; KEGG: drm:Dred_0738 phosphodiesterase; PFAM: metallophosphoesterase; SPTR: Phosphodiesterase, MJ0936 family; TIGRFAM: phosphodiesterase, MJ0936 family; PFAM: Calcineurin-like phosphoesterase; TIGRFAM: phosphoesterase, MJ0936 family.
       0.537
Toce_0733
BioY protein; COGs: COG1268 conserved hypothetical protein; InterPro IPR003784; KEGG: tte:TTE0777 uncharacterized ACR; PFAM: BioY protein; SPTR: Uncharacterized ACR; PFAM: BioY family.
 
    0.511
Toce_1938
DNA polymerase beta domain protein region; InterPro IPR002934; KEGG: chy:CHY_1896 nucleotidyltransferase domain-containing protein; PFAM: DNA polymerase beta domain protein region; SPTR: Nucleotidyltransferase domain protein; PFAM: Nucleotidyltransferase domain.
  
     0.474
Toce_2162
Protein of unknown function DUF86; COGs: COG2445 conserved hypothetical protein; InterPro IPR008201; KEGG: ate:Athe_0224 protein of unknown function DUF86; PFAM: protein of unknown function DUF86; SPTR: Putative toxin-antitoxin system, antitoxin component; PFAM: Protein of unknown function DUF86.
  
     0.426
Toce_1490
COGs: COG1757 Na+/H+ antiporter; InterPro IPR004770:IPR018461; KEGG: aoe:Clos_2497 Na+/H+ antiporter NhaC; PFAM: Na+/H+ antiporter NhaC-like; SPTR: Na+/H+ antiporter NhaC; TIGRFAM: Na+/H+ antiporter NhaC; PFAM: Na+/H+ antiporter family; TIGRFAM: Na+/H+ antiporter NhaC.
       0.415
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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