| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Toce_1493 | Toce_1495 | Toce_1493 | Toce_1495 | Protein of unknown function DUF1284; COGs: COG3543 conserved hypothetical protein; InterPro IPR009702; KEGG: adg:Adeg_0990 protein of unknown function DUF1284; PFAM: protein of unknown function DUF1284; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF1284). | Polynucleotide adenylyltransferase/metal dependent phosphohydrolase; COGs: COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; InterPro IPR002646:IPR006674; KEGG: bhy:BHWA1_01411 polyA polymerase; PFAM: Polynucleotide adenylyltransferase region; metal-dependent phosphohydrolase HD sub domain; SPTR: Uncharacterized domain HDIG-containing protein; PFAM: HD domain; Poly A polymerase head domain. | 0.557 |
| Toce_1493 | Toce_1496 | Toce_1493 | Toce_1496 | Protein of unknown function DUF1284; COGs: COG3543 conserved hypothetical protein; InterPro IPR009702; KEGG: adg:Adeg_0990 protein of unknown function DUF1284; PFAM: protein of unknown function DUF1284; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF1284). | Phosphodiesterase, MJ0936 family; COGs: COG0622 phosphoesterase; InterPro IPR000979:IPR004843; KEGG: drm:Dred_0738 phosphodiesterase; PFAM: metallophosphoesterase; SPTR: Phosphodiesterase, MJ0936 family; TIGRFAM: phosphodiesterase, MJ0936 family; PFAM: Calcineurin-like phosphoesterase; TIGRFAM: phosphoesterase, MJ0936 family. | 0.537 |
| Toce_1495 | Toce_1493 | Toce_1495 | Toce_1493 | Polynucleotide adenylyltransferase/metal dependent phosphohydrolase; COGs: COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; InterPro IPR002646:IPR006674; KEGG: bhy:BHWA1_01411 polyA polymerase; PFAM: Polynucleotide adenylyltransferase region; metal-dependent phosphohydrolase HD sub domain; SPTR: Uncharacterized domain HDIG-containing protein; PFAM: HD domain; Poly A polymerase head domain. | Protein of unknown function DUF1284; COGs: COG3543 conserved hypothetical protein; InterPro IPR009702; KEGG: adg:Adeg_0990 protein of unknown function DUF1284; PFAM: protein of unknown function DUF1284; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF1284). | 0.557 |
| Toce_1495 | Toce_1496 | Toce_1495 | Toce_1496 | Polynucleotide adenylyltransferase/metal dependent phosphohydrolase; COGs: COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; InterPro IPR002646:IPR006674; KEGG: bhy:BHWA1_01411 polyA polymerase; PFAM: Polynucleotide adenylyltransferase region; metal-dependent phosphohydrolase HD sub domain; SPTR: Uncharacterized domain HDIG-containing protein; PFAM: HD domain; Poly A polymerase head domain. | Phosphodiesterase, MJ0936 family; COGs: COG0622 phosphoesterase; InterPro IPR000979:IPR004843; KEGG: drm:Dred_0738 phosphodiesterase; PFAM: metallophosphoesterase; SPTR: Phosphodiesterase, MJ0936 family; TIGRFAM: phosphodiesterase, MJ0936 family; PFAM: Calcineurin-like phosphoesterase; TIGRFAM: phosphoesterase, MJ0936 family. | 0.802 |
| Toce_1495 | Toce_1695 | Toce_1495 | Toce_1695 | Polynucleotide adenylyltransferase/metal dependent phosphohydrolase; COGs: COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; InterPro IPR002646:IPR006674; KEGG: bhy:BHWA1_01411 polyA polymerase; PFAM: Polynucleotide adenylyltransferase region; metal-dependent phosphohydrolase HD sub domain; SPTR: Uncharacterized domain HDIG-containing protein; PFAM: HD domain; Poly A polymerase head domain. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.641 |
| Toce_1495 | birA | Toce_1495 | Toce_0887 | Polynucleotide adenylyltransferase/metal dependent phosphohydrolase; COGs: COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; InterPro IPR002646:IPR006674; KEGG: bhy:BHWA1_01411 polyA polymerase; PFAM: Polynucleotide adenylyltransferase region; metal-dependent phosphohydrolase HD sub domain; SPTR: Uncharacterized domain HDIG-containing protein; PFAM: HD domain; Poly A polymerase head domain. | biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.878 |
| Toce_1495 | dapB | Toce_1495 | Toce_0889 | Polynucleotide adenylyltransferase/metal dependent phosphohydrolase; COGs: COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; InterPro IPR002646:IPR006674; KEGG: bhy:BHWA1_01411 polyA polymerase; PFAM: Polynucleotide adenylyltransferase region; metal-dependent phosphohydrolase HD sub domain; SPTR: Uncharacterized domain HDIG-containing protein; PFAM: HD domain; Poly A polymerase head domain. | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | 0.811 |
| Toce_1495 | glmM | Toce_1495 | Toce_1968 | Polynucleotide adenylyltransferase/metal dependent phosphohydrolase; COGs: COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; InterPro IPR002646:IPR006674; KEGG: bhy:BHWA1_01411 polyA polymerase; PFAM: Polynucleotide adenylyltransferase region; metal-dependent phosphohydrolase HD sub domain; SPTR: Uncharacterized domain HDIG-containing protein; PFAM: HD domain; Poly A polymerase head domain. | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.795 |
| Toce_1495 | hfq | Toce_1495 | Toce_1186 | Polynucleotide adenylyltransferase/metal dependent phosphohydrolase; COGs: COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; InterPro IPR002646:IPR006674; KEGG: bhy:BHWA1_01411 polyA polymerase; PFAM: Polynucleotide adenylyltransferase region; metal-dependent phosphohydrolase HD sub domain; SPTR: Uncharacterized domain HDIG-containing protein; PFAM: HD domain; Poly A polymerase head domain. | RNA-binding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.618 |
| Toce_1495 | metG | Toce_1495 | Toce_0028 | Polynucleotide adenylyltransferase/metal dependent phosphohydrolase; COGs: COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; InterPro IPR002646:IPR006674; KEGG: bhy:BHWA1_01411 polyA polymerase; PFAM: Polynucleotide adenylyltransferase region; metal-dependent phosphohydrolase HD sub domain; SPTR: Uncharacterized domain HDIG-containing protein; PFAM: HD domain; Poly A polymerase head domain. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.582 |
| Toce_1495 | pnp | Toce_1495 | Toce_1231 | Polynucleotide adenylyltransferase/metal dependent phosphohydrolase; COGs: COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; InterPro IPR002646:IPR006674; KEGG: bhy:BHWA1_01411 polyA polymerase; PFAM: Polynucleotide adenylyltransferase region; metal-dependent phosphohydrolase HD sub domain; SPTR: Uncharacterized domain HDIG-containing protein; PFAM: HD domain; Poly A polymerase head domain. | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.630 |
| Toce_1495 | polA | Toce_1495 | Toce_1653 | Polynucleotide adenylyltransferase/metal dependent phosphohydrolase; COGs: COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; InterPro IPR002646:IPR006674; KEGG: bhy:BHWA1_01411 polyA polymerase; PFAM: Polynucleotide adenylyltransferase region; metal-dependent phosphohydrolase HD sub domain; SPTR: Uncharacterized domain HDIG-containing protein; PFAM: HD domain; Poly A polymerase head domain. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.567 |
| Toce_1496 | Toce_1493 | Toce_1496 | Toce_1493 | Phosphodiesterase, MJ0936 family; COGs: COG0622 phosphoesterase; InterPro IPR000979:IPR004843; KEGG: drm:Dred_0738 phosphodiesterase; PFAM: metallophosphoesterase; SPTR: Phosphodiesterase, MJ0936 family; TIGRFAM: phosphodiesterase, MJ0936 family; PFAM: Calcineurin-like phosphoesterase; TIGRFAM: phosphoesterase, MJ0936 family. | Protein of unknown function DUF1284; COGs: COG3543 conserved hypothetical protein; InterPro IPR009702; KEGG: adg:Adeg_0990 protein of unknown function DUF1284; PFAM: protein of unknown function DUF1284; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF1284). | 0.537 |
| Toce_1496 | Toce_1495 | Toce_1496 | Toce_1495 | Phosphodiesterase, MJ0936 family; COGs: COG0622 phosphoesterase; InterPro IPR000979:IPR004843; KEGG: drm:Dred_0738 phosphodiesterase; PFAM: metallophosphoesterase; SPTR: Phosphodiesterase, MJ0936 family; TIGRFAM: phosphodiesterase, MJ0936 family; PFAM: Calcineurin-like phosphoesterase; TIGRFAM: phosphoesterase, MJ0936 family. | Polynucleotide adenylyltransferase/metal dependent phosphohydrolase; COGs: COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; InterPro IPR002646:IPR006674; KEGG: bhy:BHWA1_01411 polyA polymerase; PFAM: Polynucleotide adenylyltransferase region; metal-dependent phosphohydrolase HD sub domain; SPTR: Uncharacterized domain HDIG-containing protein; PFAM: HD domain; Poly A polymerase head domain. | 0.802 |
| Toce_1695 | Toce_1495 | Toce_1695 | Toce_1495 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Polynucleotide adenylyltransferase/metal dependent phosphohydrolase; COGs: COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; InterPro IPR002646:IPR006674; KEGG: bhy:BHWA1_01411 polyA polymerase; PFAM: Polynucleotide adenylyltransferase region; metal-dependent phosphohydrolase HD sub domain; SPTR: Uncharacterized domain HDIG-containing protein; PFAM: HD domain; Poly A polymerase head domain. | 0.641 |
| Toce_1695 | birA | Toce_1695 | Toce_0887 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.729 |
| Toce_1695 | dapB | Toce_1695 | Toce_0889 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | 0.545 |
| Toce_1695 | polA | Toce_1695 | Toce_1653 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.661 |
| birA | Toce_1495 | Toce_0887 | Toce_1495 | biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Polynucleotide adenylyltransferase/metal dependent phosphohydrolase; COGs: COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; InterPro IPR002646:IPR006674; KEGG: bhy:BHWA1_01411 polyA polymerase; PFAM: Polynucleotide adenylyltransferase region; metal-dependent phosphohydrolase HD sub domain; SPTR: Uncharacterized domain HDIG-containing protein; PFAM: HD domain; Poly A polymerase head domain. | 0.878 |
| birA | Toce_1695 | Toce_0887 | Toce_1695 | biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.729 |