Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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Toce_1520Polyprenyl synthetase; COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR000092; KEGG: dsy:DSY2212 hypothetical protein; PFAM: Polyprenyl synthetase; SPTR: Putative uncharacterized protein; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. (326 aa)    
Predicted Functional Partners:
ispH
Hydroxymethylbutenyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.
 
  
 0.735
Toce_1588
COGs: COG0438 Glycosyltransferase; InterProIPR001296:IPR013216:IPR001173:IPR019734:IPR 013026:IPR000276; KEGG: tnp:Tnap_0554 glycosyl transferase family 2; PFAM: glycosyl transferase family 2; Methyltransferase type 11; glycosyl transferase group 1; SMART: Tetratricopeptide repeat; SPTR: Glycosyl transferase family 2; PFAM: Methyltransferase domain; Glycosyl transferases group 1; Glycosyl transferase family 2.
  
 
 0.680
Toce_1253
Undecaprenyl pyrophosphate synthetase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
 
  
 0.658
Toce_0607
Arsenite methyltransferase; COGs: COG2226 Methylase involved in ubiquinone/menaquinone biosynthesis; InterPro IPR013216; KEGG: sus:Acid_4410 arsenite S-adenosylmethyltransferase; PFAM: Methyltransferase type 11; PRIAM: Arsenite methyltransferase; SPTR: Methyltransferase type 11; PFAM: Methyltransferase domain.
  
 
 0.532
rnj
RNA-metabolising metallo-beta-lactamase; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
  
    0.531
Toce_1940
Beta-lactamase domain-containing protein; COGs: COG0595 hydrolase of the metallo-beta-lactamase superfamily; KEGG: dau:Daud_0808 beta-lactamase domain-containing protein; SPTR: Beta-lactamase domain protein; PFAM: Metallo-beta-lactamase superfamily; RNA-metabolising metallo-beta-lactamase.
  
    0.531
Toce_1519
Regulatory protein TetR; InterPro IPR001647; KEGG: ssa:SSA_1768 TetR/AcrR family transcriptional regulator; PFAM: regulatory protein TetR; SPTR: Transcriptional regulator, TetR/AcrR family, putative; PFAM: Bacterial regulatory proteins, tetR family.
     
 0.500
Toce_1521
Protein of unknown function DUF2600; InterPro IPR019712; KEGG: dhd:Dhaf_3343 hypothetical protein; PFAM: Protein of unknown function DUF2600; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF2600).
  
   
 0.486
xseB
Exodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family.
  
  
 0.463
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
     
 0.460
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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