Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
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Toce_1531C_GCAxxG_C_C family protein; InterPro IPR010181:IPR000834; KEGG: amt:Amet_3720 C_GCAxxG_C_C family protein; PFAM: C_GCAxxG_C_C family protein; SPTR: C_GCAxxG_C_C family protein; TIGRFAM: C_GCAxxG_C_C family protein; PFAM: Putative redox-active protein (C_GCAxxG_C_C); TIGRFAM: C_GCAxxG_C_C family probable redox protein. (158 aa)    
Predicted Functional Partners:
Toce_1530
C4-dicarboxylate transporter/malic acid transport protein; COGs: COG1275 Tellurite resistance protein and related permease; InterPro IPR004695; KEGG: amt:Amet_3721 C4-dicarboxylate transporter/malic acid transport protein; PFAM: C4-dicarboxylate transporter/malic acid transport protein; SPTR: C4-dicarboxylate transporter/malic acid transport protein; PFAM: C4-dicarboxylate transporter/malic acid transport protein.
 
   
 0.948
clpX
ATP-dependent Clp protease ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
   
 
 0.823
Toce_1225
COGs: COG0740 Protease subunit of ATP-dependent Clp protease; InterPro IPR001907; KEGG: mta:Moth_1071 ATP-dependent Clp protease proteolytic subunit ClpP; PFAM: peptidase S14 ClpP; SPTR: ATP-dependent Clp protease proteolytic subunit ClpP; PFAM: Clp protease.
    
 
 0.731
clpP
ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
    
 
 0.731
birA
biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
  
  
 0.705
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
  
  
 0.575
Toce_1695
Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
     
 0.569
pheT
COGs: COG0072 Phenylalanyl-tRNA synthetase beta subunit; InterProIPR004532:IPR002547:IPR005146:IPR005147:IPR 005121; KEGG: tit:Thit_1516 phenylalanyl-tRNA synthetase, beta subunit; PFAM: B3/4 domain protein; t-RNA-binding domain protein; tRNA synthetase B5; ferredoxin-fold anticodon-binding; PRIAM: Phenylalanine--tRNA ligase; SPTR: Phenylalanyl-tRNA synthetase, beta subunit; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; PFAM: tRNA synthetases class II core domain (F); tRNA synthetase B5 domain; B3/4 domain; Ferredoxin-fold anticodon binding domain; Putative tRNA binding domain; [...]
  
  
 0.552
aroK
3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the shikimate kinase family.
     
 0.542
Toce_0206
KEGG: tpd:Teth39_0430 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.535
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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