| node1 | node2 | node1 annotation | node2 annotation | score |
| Toce_0626 | Toce_1535 | COGs: COG1751 conserved hypothetical protein; InterPro IPR005829:IPR015074; KEGG: csc:Csac_1944 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Pyruvate kinase, alpha/beta domain. | COGs: COG1962 Tetrahydromethanopterin S-methyltransferase subunit H; InterPro IPR002856; KEGG: mch:Mchl_5727 tetrahydromethanopterin S-methyltransferase subunit H; PFAM: Tetrahydromethanopterin S-methyltransferase MtrH subunit; PRIAM: Tetrahydromethanopterin S-methyltransferase; SPTR: CmuB; PFAM: Tetrahydromethanopterin S-methyltransferase MtrH subunit; TIGRFAM: N5-methyltetrahydromethanopterin:coenzyme M methyltransferase subunit H. | 0.499 |
| Toce_0706 | Toce_1535 | Methyltransferase cognate corrinoid protein; COGs: COG5012 cobalamin binding protein; InterPro IPR006158:IPR003759:IPR012741; KEGG: swo:Swol_0418 cobalamin-dependent methionine synthase, B12-binding; PFAM: cobalamin B12-binding domain protein; Methionine synthase B12-binding module cap domain protein; SPTR: Dimethylamine corrinoid protein; TIGRFAM: methyltransferase cognate corrinoid protein; PFAM: B12 binding domain; TIGRFAM: methyltransferase cognate corrinoid proteins, Methanosarcina family. | COGs: COG1962 Tetrahydromethanopterin S-methyltransferase subunit H; InterPro IPR002856; KEGG: mch:Mchl_5727 tetrahydromethanopterin S-methyltransferase subunit H; PFAM: Tetrahydromethanopterin S-methyltransferase MtrH subunit; PRIAM: Tetrahydromethanopterin S-methyltransferase; SPTR: CmuB; PFAM: Tetrahydromethanopterin S-methyltransferase MtrH subunit; TIGRFAM: N5-methyltetrahydromethanopterin:coenzyme M methyltransferase subunit H. | 0.904 |
| Toce_0788 | Toce_0791 | KEGG: dhd:Dhaf_2572 protein of unknown function DUF1638; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF1638). | KEGG: amt:Amet_2095 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Uroporphyrinogen decarboxylase (URO-D). | 0.783 |
| Toce_0788 | Toce_0810 | KEGG: dhd:Dhaf_2572 protein of unknown function DUF1638; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF1638). | COGs: COG2069 CO dehydrogenase/acetyl-CoA synthase delta subunit (corrinoid Fe-S protein); InterPro IPR016041; KEGG: amt:Amet_2025 acetyl-CoA decarbonylase/synthase complex subunit delta; PFAM: CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel; SPTR: CO dehydrogenase/acetyl-CoA synthase delta subunit; PFAM: CO dehydrogenase/acetyl-CoA synthase delta subunit. | 0.452 |
| Toce_0788 | Toce_0811 | KEGG: dhd:Dhaf_2572 protein of unknown function DUF1638; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF1638). | COGs: COG1456 CO dehydrogenase/acetyl-CoA synthase gamma subunit (corrinoid Fe-S protein); InterPro IPR016218:IPR007202:IPR016041; KEGG: amt:Amet_2026 acetyl-CoA decarbonylase/synthase complex subunit gamma; PFAM: CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel; Fe-S cluster domain protein; SPTR: CO dehydrogenase/acetyl-CoA synthase delta subunit; PFAM: Putative Fe-S cluster; CO dehydrogenase/acetyl-CoA synthase delta subunit. | 0.456 |
| Toce_0788 | Toce_1533 | KEGG: dhd:Dhaf_2572 protein of unknown function DUF1638; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF1638). | Methyltransferase MtaA/CmuA family; COGs: COG5012 cobalamin binding protein; InterPro IPR006360:IPR000257:IPR003759:IPR006158; KEGG: mch:Mchl_5697 methyltransferase MtaA/CmuA family; PFAM: cobalamin B12-binding domain protein; Methionine synthase B12-binding module cap domain protein; Uroporphyrinogen decarboxylase (URO-D); SPTR: Methyltransferase/corrinoid CmuA; TIGRFAM: methyltransferase MtaA/CmuA family; PFAM: Uroporphyrinogen decarboxylase (URO-D); B12 binding domain; TIGRFAM: methylmalonyl-CoA mutase C-terminal domain; methyltransferase, MtaA/CmuA family; Belongs to the uroporphyr [...] | 0.404 |
| Toce_0788 | Toce_1534 | KEGG: dhd:Dhaf_2572 protein of unknown function DUF1638; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF1638). | KEGG: mch:Mchl_5728 hypothetical protein; SPTR: Methyltransferase CmuC; PFAM: Uroporphyrinogen decarboxylase (URO-D). | 0.634 |
| Toce_0788 | Toce_1535 | KEGG: dhd:Dhaf_2572 protein of unknown function DUF1638; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF1638). | COGs: COG1962 Tetrahydromethanopterin S-methyltransferase subunit H; InterPro IPR002856; KEGG: mch:Mchl_5727 tetrahydromethanopterin S-methyltransferase subunit H; PFAM: Tetrahydromethanopterin S-methyltransferase MtrH subunit; PRIAM: Tetrahydromethanopterin S-methyltransferase; SPTR: CmuB; PFAM: Tetrahydromethanopterin S-methyltransferase MtrH subunit; TIGRFAM: N5-methyltetrahydromethanopterin:coenzyme M methyltransferase subunit H. | 0.507 |
| Toce_0791 | Toce_0788 | KEGG: amt:Amet_2095 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Uroporphyrinogen decarboxylase (URO-D). | KEGG: dhd:Dhaf_2572 protein of unknown function DUF1638; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF1638). | 0.783 |
| Toce_0791 | Toce_0810 | KEGG: amt:Amet_2095 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Uroporphyrinogen decarboxylase (URO-D). | COGs: COG2069 CO dehydrogenase/acetyl-CoA synthase delta subunit (corrinoid Fe-S protein); InterPro IPR016041; KEGG: amt:Amet_2025 acetyl-CoA decarbonylase/synthase complex subunit delta; PFAM: CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel; SPTR: CO dehydrogenase/acetyl-CoA synthase delta subunit; PFAM: CO dehydrogenase/acetyl-CoA synthase delta subunit. | 0.411 |
| Toce_0791 | Toce_0811 | KEGG: amt:Amet_2095 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Uroporphyrinogen decarboxylase (URO-D). | COGs: COG1456 CO dehydrogenase/acetyl-CoA synthase gamma subunit (corrinoid Fe-S protein); InterPro IPR016218:IPR007202:IPR016041; KEGG: amt:Amet_2026 acetyl-CoA decarbonylase/synthase complex subunit gamma; PFAM: CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel; Fe-S cluster domain protein; SPTR: CO dehydrogenase/acetyl-CoA synthase delta subunit; PFAM: Putative Fe-S cluster; CO dehydrogenase/acetyl-CoA synthase delta subunit. | 0.405 |
| Toce_0791 | Toce_1534 | KEGG: amt:Amet_2095 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Uroporphyrinogen decarboxylase (URO-D). | KEGG: mch:Mchl_5728 hypothetical protein; SPTR: Methyltransferase CmuC; PFAM: Uroporphyrinogen decarboxylase (URO-D). | 0.484 |
| Toce_0791 | Toce_1535 | KEGG: amt:Amet_2095 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Uroporphyrinogen decarboxylase (URO-D). | COGs: COG1962 Tetrahydromethanopterin S-methyltransferase subunit H; InterPro IPR002856; KEGG: mch:Mchl_5727 tetrahydromethanopterin S-methyltransferase subunit H; PFAM: Tetrahydromethanopterin S-methyltransferase MtrH subunit; PRIAM: Tetrahydromethanopterin S-methyltransferase; SPTR: CmuB; PFAM: Tetrahydromethanopterin S-methyltransferase MtrH subunit; TIGRFAM: N5-methyltetrahydromethanopterin:coenzyme M methyltransferase subunit H. | 0.522 |
| Toce_0810 | Toce_0788 | COGs: COG2069 CO dehydrogenase/acetyl-CoA synthase delta subunit (corrinoid Fe-S protein); InterPro IPR016041; KEGG: amt:Amet_2025 acetyl-CoA decarbonylase/synthase complex subunit delta; PFAM: CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel; SPTR: CO dehydrogenase/acetyl-CoA synthase delta subunit; PFAM: CO dehydrogenase/acetyl-CoA synthase delta subunit. | KEGG: dhd:Dhaf_2572 protein of unknown function DUF1638; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF1638). | 0.452 |
| Toce_0810 | Toce_0791 | COGs: COG2069 CO dehydrogenase/acetyl-CoA synthase delta subunit (corrinoid Fe-S protein); InterPro IPR016041; KEGG: amt:Amet_2025 acetyl-CoA decarbonylase/synthase complex subunit delta; PFAM: CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel; SPTR: CO dehydrogenase/acetyl-CoA synthase delta subunit; PFAM: CO dehydrogenase/acetyl-CoA synthase delta subunit. | KEGG: amt:Amet_2095 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Uroporphyrinogen decarboxylase (URO-D). | 0.411 |
| Toce_0810 | Toce_0811 | COGs: COG2069 CO dehydrogenase/acetyl-CoA synthase delta subunit (corrinoid Fe-S protein); InterPro IPR016041; KEGG: amt:Amet_2025 acetyl-CoA decarbonylase/synthase complex subunit delta; PFAM: CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel; SPTR: CO dehydrogenase/acetyl-CoA synthase delta subunit; PFAM: CO dehydrogenase/acetyl-CoA synthase delta subunit. | COGs: COG1456 CO dehydrogenase/acetyl-CoA synthase gamma subunit (corrinoid Fe-S protein); InterPro IPR016218:IPR007202:IPR016041; KEGG: amt:Amet_2026 acetyl-CoA decarbonylase/synthase complex subunit gamma; PFAM: CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel; Fe-S cluster domain protein; SPTR: CO dehydrogenase/acetyl-CoA synthase delta subunit; PFAM: Putative Fe-S cluster; CO dehydrogenase/acetyl-CoA synthase delta subunit. | 0.999 |
| Toce_0810 | Toce_1535 | COGs: COG2069 CO dehydrogenase/acetyl-CoA synthase delta subunit (corrinoid Fe-S protein); InterPro IPR016041; KEGG: amt:Amet_2025 acetyl-CoA decarbonylase/synthase complex subunit delta; PFAM: CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel; SPTR: CO dehydrogenase/acetyl-CoA synthase delta subunit; PFAM: CO dehydrogenase/acetyl-CoA synthase delta subunit. | COGs: COG1962 Tetrahydromethanopterin S-methyltransferase subunit H; InterPro IPR002856; KEGG: mch:Mchl_5727 tetrahydromethanopterin S-methyltransferase subunit H; PFAM: Tetrahydromethanopterin S-methyltransferase MtrH subunit; PRIAM: Tetrahydromethanopterin S-methyltransferase; SPTR: CmuB; PFAM: Tetrahydromethanopterin S-methyltransferase MtrH subunit; TIGRFAM: N5-methyltetrahydromethanopterin:coenzyme M methyltransferase subunit H. | 0.914 |
| Toce_0811 | Toce_0788 | COGs: COG1456 CO dehydrogenase/acetyl-CoA synthase gamma subunit (corrinoid Fe-S protein); InterPro IPR016218:IPR007202:IPR016041; KEGG: amt:Amet_2026 acetyl-CoA decarbonylase/synthase complex subunit gamma; PFAM: CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel; Fe-S cluster domain protein; SPTR: CO dehydrogenase/acetyl-CoA synthase delta subunit; PFAM: Putative Fe-S cluster; CO dehydrogenase/acetyl-CoA synthase delta subunit. | KEGG: dhd:Dhaf_2572 protein of unknown function DUF1638; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF1638). | 0.456 |
| Toce_0811 | Toce_0791 | COGs: COG1456 CO dehydrogenase/acetyl-CoA synthase gamma subunit (corrinoid Fe-S protein); InterPro IPR016218:IPR007202:IPR016041; KEGG: amt:Amet_2026 acetyl-CoA decarbonylase/synthase complex subunit gamma; PFAM: CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel; Fe-S cluster domain protein; SPTR: CO dehydrogenase/acetyl-CoA synthase delta subunit; PFAM: Putative Fe-S cluster; CO dehydrogenase/acetyl-CoA synthase delta subunit. | KEGG: amt:Amet_2095 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Uroporphyrinogen decarboxylase (URO-D). | 0.405 |
| Toce_0811 | Toce_0810 | COGs: COG1456 CO dehydrogenase/acetyl-CoA synthase gamma subunit (corrinoid Fe-S protein); InterPro IPR016218:IPR007202:IPR016041; KEGG: amt:Amet_2026 acetyl-CoA decarbonylase/synthase complex subunit gamma; PFAM: CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel; Fe-S cluster domain protein; SPTR: CO dehydrogenase/acetyl-CoA synthase delta subunit; PFAM: Putative Fe-S cluster; CO dehydrogenase/acetyl-CoA synthase delta subunit. | COGs: COG2069 CO dehydrogenase/acetyl-CoA synthase delta subunit (corrinoid Fe-S protein); InterPro IPR016041; KEGG: amt:Amet_2025 acetyl-CoA decarbonylase/synthase complex subunit delta; PFAM: CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel; SPTR: CO dehydrogenase/acetyl-CoA synthase delta subunit; PFAM: CO dehydrogenase/acetyl-CoA synthase delta subunit. | 0.999 |