Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
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Toce_1536HPP family protein; COGs: COG3448 CBS-domain-containing membrane protein; InterPro IPR007065; KEGG: drm:Dred_2943 HPP family protein+B94; PFAM: HPP family protein; SPTR: HPP family protein+B94; PFAM: HPP family. (168 aa)    
Predicted Functional Partners:
Toce_1534
KEGG: mch:Mchl_5728 hypothetical protein; SPTR: Methyltransferase CmuC; PFAM: Uroporphyrinogen decarboxylase (URO-D).
 
     0.861
Toce_1535
COGs: COG1962 Tetrahydromethanopterin S-methyltransferase subunit H; InterPro IPR002856; KEGG: mch:Mchl_5727 tetrahydromethanopterin S-methyltransferase subunit H; PFAM: Tetrahydromethanopterin S-methyltransferase MtrH subunit; PRIAM: Tetrahydromethanopterin S-methyltransferase; SPTR: CmuB; PFAM: Tetrahydromethanopterin S-methyltransferase MtrH subunit; TIGRFAM: N5-methyltetrahydromethanopterin:coenzyme M methyltransferase subunit H.
 
     0.853
Toce_1533
Methyltransferase MtaA/CmuA family; COGs: COG5012 cobalamin binding protein; InterPro IPR006360:IPR000257:IPR003759:IPR006158; KEGG: mch:Mchl_5697 methyltransferase MtaA/CmuA family; PFAM: cobalamin B12-binding domain protein; Methionine synthase B12-binding module cap domain protein; Uroporphyrinogen decarboxylase (URO-D); SPTR: Methyltransferase/corrinoid CmuA; TIGRFAM: methyltransferase MtaA/CmuA family; PFAM: Uroporphyrinogen decarboxylase (URO-D); B12 binding domain; TIGRFAM: methylmalonyl-CoA mutase C-terminal domain; methyltransferase, MtaA/CmuA family; Belongs to the uroporphyr [...]
 
     0.715
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
     
 0.696
Toce_0853
COGs: COG0123 Deacetylase including yeast histone deacetylase and acetoin utilization protein; InterPro IPR000286; KEGG: tte:TTE1122 deacetylase; PFAM: histone deacetylase superfamily; SPTR: Deacetylases, including yeast histone deacetylase and acetoin utilization protein; PFAM: Histone deacetylase domain.
 
  
 0.636
Toce_1532
Hypothetical protein; KEGG: sfu:Sfum_2544 FmdB family regulatory protein; SPTR: Putative transporter; PFAM: Zinc ribbon domain.
       0.510
Toce_1537
InterPro IPR010093:IPR000551; KEGG: ttr:Tter_2677 DNA binding domain protein, excisionase family; PFAM: regulatory protein MerR; SPTR: DNA binding domain protein, excisionase family; TIGRFAM: DNA binding domain protein, excisionase family; TIGRFAM: DNA binding domain, excisionase family.
       0.433
Toce_0347
S-layer domain protein; InterPro IPR001119:IPR001330; KEGG: pth:PTH_1483 hypothetical protein; PFAM: S-layer domain protein; Prenyltransferase/squalene oxidase; SPTR: Hypothetical membrane protein; PFAM: Prenyltransferase and squalene oxidase repeat; S-layer homology domain.
  
     0.424
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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