STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
Toce_1540Anti-anti-sigma factor; InterPro IPR003658:IPR002645; KEGG: mta:Moth_0393 anti-sigma-factor antagonist domain-containing protein; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; SPTR: Anti-sigma-factor antagonist (STAS) domain protein; TIGRFAM: anti-anti-sigma factor; PFAM: STAS domain; TIGRFAM: anti-anti-sigma factor. (103 aa)    
Predicted Functional Partners:
Toce_1541
Protein serine/threonine phosphatase; COGs: COG2208 Serine phosphatase RsbU regulator of sigma subunit; InterPro IPR010822:IPR001932; KEGG: mta:Moth_0392 serine phosphatase; PFAM: Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein; SPTR: Serine phosphatase; PFAM: Stage II sporulation protein E (SpoIIE).
 
 
 0.981
Toce_1543
ATP-binding region ATPase domain protein; InterPro IPR003594; KEGG: mta:Moth_0388 putative anti-sigma regulatory factor (serine/threonine protein kinase); PFAM: ATP-binding region ATPase domain protein; SPTR: Putative anti-sigma regulatory factor (Serine/threonine protein kinase); PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
  
 
 0.976
Toce_1542
Anti-sigma-factor antagonist; COGs: COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); InterPro IPR003658:IPR002645; KEGG: mta:Moth_0391 anti-sigma-factor antagonist domain-containing protein; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; SPTR: Anti-sigma factor antagonist; TIGRFAM: anti-anti-sigma factor; PFAM: STAS domain; TIGRFAM: anti-anti-sigma factor.
 
     0.946
Toce_1539
Protein of unknown function DUF342; COGs: COG1315 polymerase most protein contain PALM domain HD hydrolase domain and Zn-ribbon domain; InterPro IPR005646; KEGG: mta:Moth_0394 hypothetical protein; PFAM: protein of unknown function DUF342; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF342); TIGRFAM: septum site-determining protein MinC.
 
     0.930
spoIIAB
Putative anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
 
 0.929
Toce_1110
COGs: COG1776 Chemotaxis protein CheC inhibitor of MCP methylation; InterPro IPR001172:IPR007597:IPR001543:IPR012826; KEGG: tte:TTE1429 flagellar motor switch protein; PFAM: surface presentation of antigens (SPOA) protein; CheC domain protein; SPTR: Chemotaxis protein CheC, inhibitor of MCP methylation; TIGRFAM: flagellar motor switch protein FliN; PFAM: Surface presentation of antigens (SPOA); CheC-like family; TIGRFAM: flagellar motor switch protein FliN.
  
   0.924
Toce_1163
Transposase mutator type; Required for the transposition of the insertion element.
  
 
 0.800
Toce_1096
COGs: COG1536 Flagellar motor switch protein; InterPro IPR000090; KEGG: cth:Cthe_0466 flagellar motor switch protein G; PFAM: flagellar motor switch protein FliG; SPTR: Flagellar motor switch protein FliG; TIGRFAM: flagellar motor switch protein FliG; PFAM: FliG C-terminal domain; TIGRFAM: flagellar motor switch protein FliG.
  
   0.783
Toce_1104
Fagellar hook-basal body protein; COGs: COG1749 Flagellar hook protein FlgE; InterPro IPR001444:IPR011491:IPR010930:IPR020013; KEGG: hmo:HM1_2230 flagellar hook protein; PFAM: protein of unknown function DUF1078 domain protein; flagellar basal body FlaE domain protein; flagellar basal body rod protein; SPTR: Putative uncharacterized protein; TIGRFAM: fagellar hook-basal body protein; PFAM: Flagella basal body rod protein; Domain of unknown function (DUF1078); Flagellar basal body protein FlaE; TIGRFAM: flagellar basal-body rod protein FlgB; fagellar hook-basal body proteins.
   
    0.758
Toce_2009
Flagellar protein FlgJ; COGs: COG3951 Rod binding protein; InterPro IPR000423:IPR019301; KEGG: tte:TTE0174 flagellum-specific muramidase; PFAM: Flagellar protein FlgJ-like; SPTR: Flagellum-specific muramidase; PFAM: Rod binding protein.
   
    0.758
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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