Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
Toce_1543ATP-binding region ATPase domain protein; InterPro IPR003594; KEGG: mta:Moth_0388 putative anti-sigma regulatory factor (serine/threonine protein kinase); PFAM: ATP-binding region ATPase domain protein; SPTR: Putative anti-sigma regulatory factor (Serine/threonine protein kinase); PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (413 aa)    
Predicted Functional Partners:
Toce_1540
Anti-anti-sigma factor; InterPro IPR003658:IPR002645; KEGG: mta:Moth_0393 anti-sigma-factor antagonist domain-containing protein; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; SPTR: Anti-sigma-factor antagonist (STAS) domain protein; TIGRFAM: anti-anti-sigma factor; PFAM: STAS domain; TIGRFAM: anti-anti-sigma factor.
  
 
 0.976
Toce_1542
Anti-sigma-factor antagonist; COGs: COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); InterPro IPR003658:IPR002645; KEGG: mta:Moth_0391 anti-sigma-factor antagonist domain-containing protein; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; SPTR: Anti-sigma factor antagonist; TIGRFAM: anti-anti-sigma factor; PFAM: STAS domain; TIGRFAM: anti-anti-sigma factor.
  
 
 0.975
Toce_1541
Protein serine/threonine phosphatase; COGs: COG2208 Serine phosphatase RsbU regulator of sigma subunit; InterPro IPR010822:IPR001932; KEGG: mta:Moth_0392 serine phosphatase; PFAM: Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein; SPTR: Serine phosphatase; PFAM: Stage II sporulation protein E (SpoIIE).
  
 
 0.936
Toce_1269
Anti-sigma-factor antagonist; COGs: COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); InterPro IPR003658:IPR014237:IPR002645; KEGG: tte:TTE1315 anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); PFAM: Sulfate transporter/antisigma-factor antagonist STAS; SPTR: Anti-sigma factor antagonist; TIGRFAM: anti-sigma F factor antagonist; anti-anti-sigma factor; PFAM: STAS domain; TIGRFAM: anti-anti-sigma factor; anti-sigma F factor antagonist; Belongs to the anti-sigma-factor antagonist family.
  
 
 0.839
Toce_1267
RNA polymerase, sigma subunit, RpoX/SigF; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
 
 0.814
Toce_1092
Flagellar basal-body rod protein FlgB; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
   
    0.758
Toce_1096
COGs: COG1536 Flagellar motor switch protein; InterPro IPR000090; KEGG: cth:Cthe_0466 flagellar motor switch protein G; PFAM: flagellar motor switch protein FliG; SPTR: Flagellar motor switch protein FliG; TIGRFAM: flagellar motor switch protein FliG; PFAM: FliG C-terminal domain; TIGRFAM: flagellar motor switch protein FliG.
   
    0.758
Toce_1100
MgtE intracellular region; InterPro IPR006668; KEGG: tte:TTE1437 hypothetical protein; PFAM: MgtE intracellular region; SPTR: Putative uncharacterized protein; PFAM: MgtE intracellular N domain.
   
    0.758
Toce_1106
MotA/TolQ/ExbB proton channel; COGs: COG1291 Flagellar motor component; InterPro IPR002898:IPR000540; KEGG: nth:Nther_1402 MotA/TolQ/ExbB proton channel; PFAM: MotA/TolQ/ExbB proton channel; SPTR: MotA/TolQ/ExbB proton channel; PFAM: MotA/TolQ/ExbB proton channel family.
   
    0.758
flgK
COGs: COG1256 Flagellar hook-associated protein; InterPro IPR002371:IPR001444:IPR010930; KEGG: tit:Thit_0470 flagellar hook-associated protein FlgK; PFAM: protein of unknown function DUF1078 domain protein; flagellar basal body rod protein; SPTR: Flagellar hook-associated protein FlgK; TIGRFAM: flagellar hook-associated protein FlgK; PFAM: Domain of unknown function (DUF1078); Flagella basal body rod protein; TIGRFAM: flagellar hook-associated protein FlgK.
   
    0.758
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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