Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Toce_1552Bilirubin oxidase; COGs: COG2132 Putative multicopper oxidase; InterPro IPR011707:IPR011706; KEGG: bcl:ABC2649 spore coat protein; PFAM: multicopper oxidase type 2; multicopper oxidase type 3; PRIAM: Bilirubin oxidase; SPTR: Spore coat protein; PFAM: Multicopper oxidase. (563 aa)    
Predicted Functional Partners:
zupT
Zinc/iron permease; Mediates zinc uptake. May also transport other divalent cations; Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.
   
 0.924
Toce_1976
Permease; COGs: COG0701 permease; InterPro IPR005524; KEGG: fno:Fnod_1485 permease; PFAM: permease; SPTR: Permease; PFAM: Predicted permease.
  
  
 0.591
Toce_1731
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG1252 NADH dehydrogenase FAD-containing subunit; InterPro IPR013027:IPR011637; KEGG: hor:Hore_14860 NADH dehydrogenase, FAD-containing subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; DoxX family protein; SPTR: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; DoxX.
 
   
 0.511
Toce_0200
Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594:IPR004358:IPR005467; KEGG: bld:BLi00981 hypothetical protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
  
 
 0.435
Toce_0459
COGs: COG0642 Signal transduction histidine kinase; InterPro IPR005467:IPR003594:IPR004358; KEGG: cbe:Cbei_4175 signal transduction histidine kinase regulating citrate/malate metabolism; PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: Signal transduction histidine kinase regulating citrate/malate metabolism; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
  
 
 0.435
Toce_0694
Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003594:IPR005467:IPR004358; KEGG: cpy:Cphy_3802 histidine kinase; PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: Histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
  
 
 0.435
Toce_0734
Copper ion binding protein; COGs: COG2608 Copper chaperone; InterPro IPR006121:IPR006122:IPR017969:IPR001802; KEGG: nth:Nther_1097 copper ion binding protein; PFAM: Heavy metal transport/detoxification protein; SPTR: Copper ion binding protein; TIGRFAM: copper ion binding protein; PFAM: Heavy-metal-associated domain; TIGRFAM: copper ion binding protein.
  
 
 0.427
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
  
    0.404
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
Server load: low (16%) [HD]