| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Toce_0200 | Toce_1552 | Toce_0200 | Toce_1552 | Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594:IPR004358:IPR005467; KEGG: bld:BLi00981 hypothetical protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. | Bilirubin oxidase; COGs: COG2132 Putative multicopper oxidase; InterPro IPR011707:IPR011706; KEGG: bcl:ABC2649 spore coat protein; PFAM: multicopper oxidase type 2; multicopper oxidase type 3; PRIAM: Bilirubin oxidase; SPTR: Spore coat protein; PFAM: Multicopper oxidase. | 0.435 |
| Toce_0459 | Toce_1552 | Toce_0459 | Toce_1552 | COGs: COG0642 Signal transduction histidine kinase; InterPro IPR005467:IPR003594:IPR004358; KEGG: cbe:Cbei_4175 signal transduction histidine kinase regulating citrate/malate metabolism; PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: Signal transduction histidine kinase regulating citrate/malate metabolism; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. | Bilirubin oxidase; COGs: COG2132 Putative multicopper oxidase; InterPro IPR011707:IPR011706; KEGG: bcl:ABC2649 spore coat protein; PFAM: multicopper oxidase type 2; multicopper oxidase type 3; PRIAM: Bilirubin oxidase; SPTR: Spore coat protein; PFAM: Multicopper oxidase. | 0.435 |
| Toce_0694 | Toce_1552 | Toce_0694 | Toce_1552 | Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003594:IPR005467:IPR004358; KEGG: cpy:Cphy_3802 histidine kinase; PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: Histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. | Bilirubin oxidase; COGs: COG2132 Putative multicopper oxidase; InterPro IPR011707:IPR011706; KEGG: bcl:ABC2649 spore coat protein; PFAM: multicopper oxidase type 2; multicopper oxidase type 3; PRIAM: Bilirubin oxidase; SPTR: Spore coat protein; PFAM: Multicopper oxidase. | 0.435 |
| Toce_0734 | Toce_1552 | Toce_0734 | Toce_1552 | Copper ion binding protein; COGs: COG2608 Copper chaperone; InterPro IPR006121:IPR006122:IPR017969:IPR001802; KEGG: nth:Nther_1097 copper ion binding protein; PFAM: Heavy metal transport/detoxification protein; SPTR: Copper ion binding protein; TIGRFAM: copper ion binding protein; PFAM: Heavy-metal-associated domain; TIGRFAM: copper ion binding protein. | Bilirubin oxidase; COGs: COG2132 Putative multicopper oxidase; InterPro IPR011707:IPR011706; KEGG: bcl:ABC2649 spore coat protein; PFAM: multicopper oxidase type 2; multicopper oxidase type 3; PRIAM: Bilirubin oxidase; SPTR: Spore coat protein; PFAM: Multicopper oxidase. | 0.427 |
| Toce_1552 | Toce_0200 | Toce_1552 | Toce_0200 | Bilirubin oxidase; COGs: COG2132 Putative multicopper oxidase; InterPro IPR011707:IPR011706; KEGG: bcl:ABC2649 spore coat protein; PFAM: multicopper oxidase type 2; multicopper oxidase type 3; PRIAM: Bilirubin oxidase; SPTR: Spore coat protein; PFAM: Multicopper oxidase. | Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594:IPR004358:IPR005467; KEGG: bld:BLi00981 hypothetical protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. | 0.435 |
| Toce_1552 | Toce_0459 | Toce_1552 | Toce_0459 | Bilirubin oxidase; COGs: COG2132 Putative multicopper oxidase; InterPro IPR011707:IPR011706; KEGG: bcl:ABC2649 spore coat protein; PFAM: multicopper oxidase type 2; multicopper oxidase type 3; PRIAM: Bilirubin oxidase; SPTR: Spore coat protein; PFAM: Multicopper oxidase. | COGs: COG0642 Signal transduction histidine kinase; InterPro IPR005467:IPR003594:IPR004358; KEGG: cbe:Cbei_4175 signal transduction histidine kinase regulating citrate/malate metabolism; PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: Signal transduction histidine kinase regulating citrate/malate metabolism; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. | 0.435 |
| Toce_1552 | Toce_0694 | Toce_1552 | Toce_0694 | Bilirubin oxidase; COGs: COG2132 Putative multicopper oxidase; InterPro IPR011707:IPR011706; KEGG: bcl:ABC2649 spore coat protein; PFAM: multicopper oxidase type 2; multicopper oxidase type 3; PRIAM: Bilirubin oxidase; SPTR: Spore coat protein; PFAM: Multicopper oxidase. | Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003594:IPR005467:IPR004358; KEGG: cpy:Cphy_3802 histidine kinase; PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: Histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. | 0.435 |
| Toce_1552 | Toce_0734 | Toce_1552 | Toce_0734 | Bilirubin oxidase; COGs: COG2132 Putative multicopper oxidase; InterPro IPR011707:IPR011706; KEGG: bcl:ABC2649 spore coat protein; PFAM: multicopper oxidase type 2; multicopper oxidase type 3; PRIAM: Bilirubin oxidase; SPTR: Spore coat protein; PFAM: Multicopper oxidase. | Copper ion binding protein; COGs: COG2608 Copper chaperone; InterPro IPR006121:IPR006122:IPR017969:IPR001802; KEGG: nth:Nther_1097 copper ion binding protein; PFAM: Heavy metal transport/detoxification protein; SPTR: Copper ion binding protein; TIGRFAM: copper ion binding protein; PFAM: Heavy-metal-associated domain; TIGRFAM: copper ion binding protein. | 0.427 |
| Toce_1552 | Toce_1731 | Toce_1552 | Toce_1731 | Bilirubin oxidase; COGs: COG2132 Putative multicopper oxidase; InterPro IPR011707:IPR011706; KEGG: bcl:ABC2649 spore coat protein; PFAM: multicopper oxidase type 2; multicopper oxidase type 3; PRIAM: Bilirubin oxidase; SPTR: Spore coat protein; PFAM: Multicopper oxidase. | FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG1252 NADH dehydrogenase FAD-containing subunit; InterPro IPR013027:IPR011637; KEGG: hor:Hore_14860 NADH dehydrogenase, FAD-containing subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; DoxX family protein; SPTR: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; DoxX. | 0.511 |
| Toce_1552 | Toce_1976 | Toce_1552 | Toce_1976 | Bilirubin oxidase; COGs: COG2132 Putative multicopper oxidase; InterPro IPR011707:IPR011706; KEGG: bcl:ABC2649 spore coat protein; PFAM: multicopper oxidase type 2; multicopper oxidase type 3; PRIAM: Bilirubin oxidase; SPTR: Spore coat protein; PFAM: Multicopper oxidase. | Permease; COGs: COG0701 permease; InterPro IPR005524; KEGG: fno:Fnod_1485 permease; PFAM: permease; SPTR: Permease; PFAM: Predicted permease. | 0.591 |
| Toce_1552 | guaA | Toce_1552 | Toce_0353 | Bilirubin oxidase; COGs: COG2132 Putative multicopper oxidase; InterPro IPR011707:IPR011706; KEGG: bcl:ABC2649 spore coat protein; PFAM: multicopper oxidase type 2; multicopper oxidase type 3; PRIAM: Bilirubin oxidase; SPTR: Spore coat protein; PFAM: Multicopper oxidase. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.404 |
| Toce_1552 | zupT | Toce_1552 | Toce_1999 | Bilirubin oxidase; COGs: COG2132 Putative multicopper oxidase; InterPro IPR011707:IPR011706; KEGG: bcl:ABC2649 spore coat protein; PFAM: multicopper oxidase type 2; multicopper oxidase type 3; PRIAM: Bilirubin oxidase; SPTR: Spore coat protein; PFAM: Multicopper oxidase. | Zinc/iron permease; Mediates zinc uptake. May also transport other divalent cations; Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily. | 0.924 |
| Toce_1731 | Toce_1552 | Toce_1731 | Toce_1552 | FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG1252 NADH dehydrogenase FAD-containing subunit; InterPro IPR013027:IPR011637; KEGG: hor:Hore_14860 NADH dehydrogenase, FAD-containing subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; DoxX family protein; SPTR: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; DoxX. | Bilirubin oxidase; COGs: COG2132 Putative multicopper oxidase; InterPro IPR011707:IPR011706; KEGG: bcl:ABC2649 spore coat protein; PFAM: multicopper oxidase type 2; multicopper oxidase type 3; PRIAM: Bilirubin oxidase; SPTR: Spore coat protein; PFAM: Multicopper oxidase. | 0.511 |
| Toce_1731 | guaA | Toce_1731 | Toce_0353 | FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG1252 NADH dehydrogenase FAD-containing subunit; InterPro IPR013027:IPR011637; KEGG: hor:Hore_14860 NADH dehydrogenase, FAD-containing subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; DoxX family protein; SPTR: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; DoxX. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.493 |
| Toce_1976 | Toce_1552 | Toce_1976 | Toce_1552 | Permease; COGs: COG0701 permease; InterPro IPR005524; KEGG: fno:Fnod_1485 permease; PFAM: permease; SPTR: Permease; PFAM: Predicted permease. | Bilirubin oxidase; COGs: COG2132 Putative multicopper oxidase; InterPro IPR011707:IPR011706; KEGG: bcl:ABC2649 spore coat protein; PFAM: multicopper oxidase type 2; multicopper oxidase type 3; PRIAM: Bilirubin oxidase; SPTR: Spore coat protein; PFAM: Multicopper oxidase. | 0.591 |
| guaA | Toce_1552 | Toce_0353 | Toce_1552 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Bilirubin oxidase; COGs: COG2132 Putative multicopper oxidase; InterPro IPR011707:IPR011706; KEGG: bcl:ABC2649 spore coat protein; PFAM: multicopper oxidase type 2; multicopper oxidase type 3; PRIAM: Bilirubin oxidase; SPTR: Spore coat protein; PFAM: Multicopper oxidase. | 0.404 |
| guaA | Toce_1731 | Toce_0353 | Toce_1731 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG1252 NADH dehydrogenase FAD-containing subunit; InterPro IPR013027:IPR011637; KEGG: hor:Hore_14860 NADH dehydrogenase, FAD-containing subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; DoxX family protein; SPTR: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; DoxX. | 0.493 |
| zupT | Toce_1552 | Toce_1999 | Toce_1552 | Zinc/iron permease; Mediates zinc uptake. May also transport other divalent cations; Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily. | Bilirubin oxidase; COGs: COG2132 Putative multicopper oxidase; InterPro IPR011707:IPR011706; KEGG: bcl:ABC2649 spore coat protein; PFAM: multicopper oxidase type 2; multicopper oxidase type 3; PRIAM: Bilirubin oxidase; SPTR: Spore coat protein; PFAM: Multicopper oxidase. | 0.924 |