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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Toce_1559Methionine gamma-lyase; COGs: COG0626 Cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR006237:IPR000277; KEGG: cko:CKO_04984 hypothetical protein; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; SPTR: Methionine gamma-lyase; TIGRFAM: methionine gamma-lyase; PFAM: Cys/Met metabolism PLP-dependent enzyme; TIGRFAM: methionine gamma-lyase; O-succinylhomoserine sulfhydrylase. (401 aa)    
Predicted Functional Partners:
Toce_0711
Cystathionine beta-synthase (acetylserine-dependent); COGs: COG0031 Cysteine synthase; InterPro IPR005856:IPR005859:IPR001216:IPR001926; KEGG: gtn:GTNG_2474 O-acetylserine lyase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: Cysteine synthase; TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases; Belongs to the cysteine synthase/cystathionine beta- synthase family.
 
 0.937
Toce_0731
COGs: COG0031 Cysteine synthase; InterPro IPR005856:IPR005859:IPR001216:IPR001926; KEGG: mta:Moth_1706 cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: Cysteine synthase; TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases; Belongs to the cysteine synthase/cystathionine beta- synthase family.
 
 0.936
metK
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
   
 0.932
Toce_1790
COGs: COG2873 O-acetylhomoserine sulfhydrylase; InterPro IPR006235:IPR000277; KEGG: tpd:Teth39_0501 O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; PRIAM: Cysteine synthase; SPTR: O-acetylhomoserine/O-acetylserine sulfhydrylase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism PLP-dependent enzyme; TIGRFAM: OAH/OAS sulfhydrylase.
 
 
0.929
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
   
 
 0.920
Toce_0155
COGs: COG0492 Thioredoxin reductase; InterPro IPR005982:IPR013027:IPR000103:IPR008255; KEGG: pth:PTH_1417 thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Thioredoxin reductase; TIGRFAM: thioredoxin reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: thioredoxin-disulfide reductase.
   
 
 0.910
Toce_1558
Putative methionine transporter, NhaC family (TC 2.A.35.1.-); COGs: COG1757 Na+/H+ antiporter; InterPro IPR018461; KEGG: nth:Nther_2679 Na+/H+ antiporter NhaC; PFAM: Na+/H+ antiporter NhaC-like; SPTR: Na+/H+ antiporter NhaC; PFAM: Na+/H+ antiporter family.
  
  
 0.725
rplL
LSU ribosomal protein L12P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family.
    
 
 0.717
Toce_1487
Pyridoxal-5'-phosphate-dependent protein beta subunit; COGs: COG0031 Cysteine synthase; InterPro IPR001926; KEGG: tte:TTE1236 threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: Threonine synthase; PFAM: Pyridoxal-phosphate dependent enzyme.
  
 
 0.678
Toce_0807
COGs: COG0685 5 10-methylenetetrahydrofolate reductase; InterPro IPR003171; KEGG: amt:Amet_2022 methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; SPTR: Methylenetetrahydrofolate reductase; PFAM: Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
  
 
 0.656
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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