STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
csrACarbon storage regulator, CsrA; A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'- UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW. (75 aa)    
Predicted Functional Partners:
fliW
Protein of unknown function DUF180; Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
 
 
 0.999
Toce_1596
COGs: COG1344 Flagellin and related hook-associated protein; InterPro IPR013384:IPR001492:IPR001029; KEGG: cth:Cthe_2242 flagellar hook-associated protein FlgL; PFAM: flagellin domain protein; SPTR: Flagellar hook-associated protein 3; TIGRFAM: flagellar hook-associated protein 3; PFAM: Bacterial flagellin N-terminal helical region; Bacterial flagellin C-terminal helical region; TIGRFAM: flagellar hook-associated protein 3.
 
  
 0.910
flgK
COGs: COG1256 Flagellar hook-associated protein; InterPro IPR002371:IPR001444:IPR010930; KEGG: tit:Thit_0470 flagellar hook-associated protein FlgK; PFAM: protein of unknown function DUF1078 domain protein; flagellar basal body rod protein; SPTR: Flagellar hook-associated protein FlgK; TIGRFAM: flagellar hook-associated protein FlgK; PFAM: Domain of unknown function (DUF1078); Flagella basal body rod protein; TIGRFAM: flagellar hook-associated protein FlgK.
 
  
 0.874
Toce_1586
Flagellin domain protein; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
 
  
 0.868
Toce_1599
InterPro IPR007412; KEGG: swo:Swol_0190 putative anti-sigma-28 factor, FlgM; PFAM: Anti-sigma-28 factor FlgM family protein; SPTR: Anti-sigma-28 factor, FlgM; TIGRFAM: Anti-sigma-28 factor FlgM family protein; PFAM: Anti-sigma-28 factor, FlgM.
  
  
 0.821
Toce_1595
KEGG: amt:Amet_0729 hypothetical protein; SPTR: Putative uncharacterized protein.
  
    0.818
Toce_1578
Flagellar protein FliS; COGs: COG1516 Flagellin-specific chaperone FliS; InterPro IPR003713; KEGG: amt:Amet_0786 flagellar protein FliS; PFAM: flagellar protein FliS; SPTR: Flagellar protein FliS; TIGRFAM: flagellar protein FliS; PFAM: Flagellar protein FliS; TIGRFAM: flagellar biosynthetic protein FliS.
 
  
 0.816
hfq
RNA-binding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.
   
  
 0.807
Toce_1588
COGs: COG0438 Glycosyltransferase; InterProIPR001296:IPR013216:IPR001173:IPR019734:IPR 013026:IPR000276; KEGG: tnp:Tnap_0554 glycosyl transferase family 2; PFAM: glycosyl transferase family 2; Methyltransferase type 11; glycosyl transferase group 1; SMART: Tetratricopeptide repeat; SPTR: Glycosyl transferase family 2; PFAM: Methyltransferase domain; Glycosyl transferases group 1; Glycosyl transferase family 2.
     
 0.804
Toce_1579
Flagellar hook-associated 2 domain protein; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
 
  
 0.751
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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