Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Toce_1595KEGG: amt:Amet_0729 hypothetical protein; SPTR: Putative uncharacterized protein. (191 aa)    
Predicted Functional Partners:
Toce_1598
FlgN family protein; InterPro IPR007809; KEGG: cce:Ccel_0093 FlgN family protein; PFAM: FlgN family protein; SPTR: FlgN family protein; PFAM: FlgN protein.
 
  
 0.910
Toce_1600
Flagellar operon protein YvyF; InterPro IPR022258; KEGG: aoe:Clos_2524 hypothetical protein; SPTR: Putative uncharacterized protein; TIGRFAM: Flagellar operon protein YvyF.
 
  
 0.896
fliW
Protein of unknown function DUF180; Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
  
  
 0.867
Toce_1596
COGs: COG1344 Flagellin and related hook-associated protein; InterPro IPR013384:IPR001492:IPR001029; KEGG: cth:Cthe_2242 flagellar hook-associated protein FlgL; PFAM: flagellin domain protein; SPTR: Flagellar hook-associated protein 3; TIGRFAM: flagellar hook-associated protein 3; PFAM: Bacterial flagellin N-terminal helical region; Bacterial flagellin C-terminal helical region; TIGRFAM: flagellar hook-associated protein 3.
 
  
 0.841
csrA
Carbon storage regulator, CsrA; A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'- UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
  
    0.804
flgK
COGs: COG1256 Flagellar hook-associated protein; InterPro IPR002371:IPR001444:IPR010930; KEGG: tit:Thit_0470 flagellar hook-associated protein FlgK; PFAM: protein of unknown function DUF1078 domain protein; flagellar basal body rod protein; SPTR: Flagellar hook-associated protein FlgK; TIGRFAM: flagellar hook-associated protein FlgK; PFAM: Domain of unknown function (DUF1078); Flagella basal body rod protein; TIGRFAM: flagellar hook-associated protein FlgK.
  
  
 0.802
Toce_1599
InterPro IPR007412; KEGG: swo:Swol_0190 putative anti-sigma-28 factor, FlgM; PFAM: Anti-sigma-28 factor FlgM family protein; SPTR: Anti-sigma-28 factor, FlgM; TIGRFAM: Anti-sigma-28 factor FlgM family protein; PFAM: Anti-sigma-28 factor, FlgM.
  
  
 0.764
Toce_2007
KEGG: swo:Swol_2165 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.700
Toce_1696
Glycosidase related protein; COGs: COG2152 glycosylase; InterPro IPR007184; KEGG: swo:Swol_1919 glycosylase-like protein; PFAM: glycosidase related protein; SPTR: Glycosylase-like protein; PFAM: Domain of unknown function (DUF377).
  
     0.624
Toce_1592
DegT/DnrJ/EryC1/StrS aminotransferase; COGs: COG0399 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; InterPro IPR000653; KEGG: tte:TTE0651 cell wall biogenesis regulatory protein; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; SPTR: Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase family; Belongs to the DegT/DnrJ/EryC1 family.
       0.609
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
Server load: low (24%) [HD]