STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Coexpression
Experiments
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[Homology]
Score
Toce_1674Transcriptional regulator, MarR family; COGs: COG1846 Transcriptional regulators; InterPro IPR000835:IPR001367; KEGG: aoe:Clos_2679 MarR family transcriptional regulator; PFAM: regulatory protein MarR; SMART: regulatory protein MarR; iron dependent repressor; SPTR: Transcriptional regulator, MarR family; PFAM: MarR family. (150 aa)    
Predicted Functional Partners:
Toce_1673
ABC transporter related protein; COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterProIPR001140:IPR003439:IPR017940:IPR003593:IPR 017871; KEGG: amt:Amet_2176 ABC transporter, transmembrane region; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase; SPTR: ABC transporter; PFAM: ABC transporter transmembrane region; ABC transporter.
 
  
 0.830
Toce_1672
ABC transporter related protein; COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterProIPR001140:IPR003439:IPR017940:IPR003593:IPR 017871; KEGG: dae:Dtox_2733 ABC transporter related; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase; SPTR: ABC transporter related; PFAM: ABC transporter transmembrane region; ABC transporter.
 
  
 0.827
Toce_0455
Transcriptional regulator, MarR family; COGs: COG1846 Transcriptional regulators; InterPro IPR000835; KEGG: cce:Ccel_1609 transcriptional regulator, MarR family; PFAM: regulatory protein MarR; SMART: regulatory protein MarR; SPTR: Transcriptional regulator, MarR family; PFAM: MarR family.
  
     0.544
uvrA
Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
  
  
 0.529
uvrB
Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
       0.519
Toce_1932
InterPro IPR001387:IPR013096; KEGG: drm:Dred_1558 cupin 2 domain-containing protein; PFAM: Cupin 2 conserved barrel domain protein; helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; SPTR: Cupin 2, conserved barrel domain protein; PFAM: Cupin domain; Helix-turn-helix.
 
 
 0.493
Toce_2170
Efflux transporter, RND family, MFP subunit; COGs: COG0845 Membrane-fusion protein; InterPro IPR003997:IPR006143:IPR000089; KEGG: tit:Thit_0217 efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; biotin/lipoyl attachment domain-containing protein; SPTR: Efflux transporter, RND family, MFP subunit; TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: HlyD family secretion protein; TIGRFAM: RND family efflux transporter, MFP subunit.
  
  
 0.485
Toce_1029
Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
     
 0.454
birA
biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
     
 0.422
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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